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Human Genetics   Research Article

Platelet parameters and expression of platelet membrane glycoprotein in childhood acute lymphoblastic leukemia

Authors: Z. Huang, W.J. Liu, Q.L. Guo, C.Y. Liu

Platelet activation and functional changes were investigated in acute lymphoblastic leukemia (ALL) to provide the basis for early diagnosis and evaluation of curative effect. Platelet parameters, immature platelet fraction (IPF%), immature platelet count (IPC), P-selectin (CD62p) (PAC-1) expression were detected in ALL, ALL-co.. Read More»

Genet. Mol. Res. 14(4):
2015.December.7.20
DOI:
10.4238/2015.December.7.20
Plant Genetics   Research Article

Comparative transcriptome analysis of self-incompatible flower stigmas and self-compatible bud stigmas following self-pollination in broccoliComparative transcriptome analysis of self-incompatible flower stigmas and self-compatible bud stigmas followingself-pollination in broccoli

Authors: H.F. Yu, J.S. Wang, X.G. Sheng, Z.Q. Zhao, Z.R. Qi H.H. Gu

DH07 is a DH line of Class I S-haplotype in broccoli (Brassica oleracea var. italica), in which stigmas of flowers show self-incompatibility (SI) and stigmas of buds show self-compatibility (SC). The molecular mechanisms that lead to stigmas at different developmental stages having different responses to self-pollination are y.. Read More»

Genet. Mol. Res. 16(1):
gmr16019018
DOI:
10.4238/gmr16019018
Animal Genetics   Research Article

Enhanced expression and significance of glycosylphosphatidylinositol anchor attachment protein 1 in colorectal cancer

Authors: G. Chen, S.Y. Li, H.Y. Cai and F.Y. Zuo

The aim of this study was to investigate the expression of glycosylphosphatidylinositol anchor attachment protein 1 (GPAA1) and its significance in patients with colorectal cancer. Fifty-two patients with primary colorectal cancer were included in this study. GPAA1 expression was detected by immunohistochemistry, reverse trans.. Read More»

Genet. Mol. Res. 13(1):
2014.January.21.19
DOI:
10.4238/2014.January.21.19
Human Genetics   Research Article

Role of interleukin-6 polymorphisms in the development of allergic rhinitis

Authors: N. Zhao1,2, H.J. Liu2, Y.Y. Sun3 and Y.Z. Li1

The aim of this study was to investigate the role played by the IL-6 rs1800795 (-174G/C) and rs1800796 (-572G>C) polymorphisms in the susceptibility to allergic rhinitis in a Chinese population. A total of 265 patients with allergic rhinitis and 265 controls from our hospital were enrolled in this study. The IL-6 rs1800795 and rs1800796 polymorphisms w.. Read More»

Genet. Mol. Res. 15(1):
gmr.15016987
DOI:
10.4238/gmr.15016987
Human Genetics   Research Article

Molecular characterization, tissue expression profile, and SNP analysis of porcine SLC13A5

Authors: L.Y. Wang, J. Jiang, H.M. Ma

Solute carrier family 13 (sodium-dependent citrate transporter member 5, SLC13A5) gene has been recently found to play an important role in intramuscular fat content in pigs. In this study, the full-length cDNA of porcine SLC13A5 was obtained from the longissimus dorsi muscle of Shaziling pigs, using the rapid amplification of.. Read More»

Genet. Mol. Res. 14(4):
2015.December.7.21
DOI:
10.4238/2015.December.7.21
Microbial Genetics   Research Article

Molecular detection by analysis of the 16S rRNA gene of fecal coliform bacteria from the two Korean Apodemus species (Apodemus agrarius and A. peninsulae)

Authors: M.M. Rahman, K.B. Yoon, S.J. Lim, M.G. Jeon, H.J. Kim, H.Y. Kim, J.Y. Cho, H.M. Chae and Y.C. Park

Wild mouse feces can disseminate zoonotic microorganisms throughout a farm, which is a great threat to human health and can lead to economic loss through contaminated agricultural produce. To assess the microbial communities, especially fecal coliform bacteria, we used two methods. First, we isolated bacterial colonies onto th.. Read More»

Genet. Mol. Res. 16(2):
gmr16029510
DOI:
10.4238/gmr16029510
Plant Genetics   Research Article

Effect of ethylene treatment on phytochemical and ethylene-related gene expression during ripening in strawberry fruit Fragaria x ananassa cv. Camino Real

Authors: P.Z. Lopes,I.M. Fornazzari, A.T. Almeida, C.W. Galv�£o,R.M. Etto, J. Inaba, R.A. Ayub

In contrast to climacteric fruits, in which ethylene is known to be pivotal, the regulation of ripening in non-climacteric fruits is not well understood. The strawberry is a typical example of a non-climacteric fruit, which has been used as a model system of these types of fruit. In this study, the effect of exogenous ethephon.. Read More»

Genet. Mol. Res. 14(4):
2015.December.7.23
DOI:
10.4238/2015.December.7.23
Plant Genetics   Research Article

Production and genetic analysis of resynthesized Brassica napus from a B. rapa landrace from the Qinghai-Tibet Plateau and B. alboglabra

Authors: H.D. Liu*, Z.G. Zhao*, D.Z. Du, C.R. Deng and G. Fu

This study aimed to reveal the genetic and epigenetic variations involved in a resynthesized Brassica napus (AACC) generated from a hybridization between a B. rapa (AA) landrace and B. alboglabra (CC). Amplified fragment length polymorphism (AFLP), methylation-sensitive amplified polymorphism, and the cDNA-AFLP technique were performed to detect changes b.. Read More»

Genet. Mol. Res. 15(1):
gmr.15017146
DOI:
10.4238/gmr.15017146
Medical Genetics   Research Article

Association of a CYP4A11 polymorphism and hypertension in the Mongolian and Han populations of China

Authors: J.Q. Liang, M.R. Yan, L. Yang, Q. Suyila, H.W. Cui and X.L. Su

Human cytochrome P450 4A11 (CYP4A11) plays a role in the regulation of blood pressure through the conversion of arachidonic acid into 20-hydroxyeicosatetraenoic acid (20-HETE). We therefore investigated the association between a CYP4A11 polymorphism (rs9333025) with hypertension in the Mongolian and Han ethnic groups. We studi.. Read More»

Genet. Mol. Res. 13(1):
2014.January.21.20
DOI:
10.4238/2014.January.21.20
Human Genetics   Research Article

Hemodynamic changes of unexplained syncope patients in head-up tilt test

Authors: X. Li, L.L. Liu, Y.J. Wan and R. Peng

The purpose of this study was to observe the hemodynamic changes of unexplained syncope patients in the head-up tilt test and their correlations with age and gender. Eighty-six patients with unexplained syncope were administered the basic head-up test and nitroglycerin provocation test with continuous monitoring and recording of electrocardiogram and bloo.. Read More»

Genet. Mol. Res. 14(1):
2015.January.30.4
DOI:
10.4238/2015.January.30.4