Pleural resection and pleural infusion chemotherapy for therapy of malignant pleural mesothelioma
Authors: J. Zhang, Q. Zhang, W. Zhao, J. Duan and T. Huang
The aim of this study was to evaluate effective treatment methods of malignant pleural mesothelioma (MPM). Twenty-three patients with MPM were cured by pleural infusion chemotherapy after surgery. Median survival time and the 1-, 2-, and 3-year survival rates were analyzed on the basis of follow-up. Median survival time of all.. Read More»
- Genet. Mol. Res. 13(1):
- 2014.January.21.17
- DOI:
- 10.4238/2014.January.21.17
Stable expression and integrated hepatitis B virus genome in a human hepatoma cell line
Authors: L.Y. Wang, Y.G. Li, K. Chen, K. Li, J.L. Qu, D.D. Qin and H. Tang
HepG2.2.15 cell is a widely used cell model for studying HBV (hepatitis B virus) in vitro. In these cells, the HBV genome is integrated in several sites of HepG2 cellular DNA. These multiple copies may have some influence on the cellular processes. We constructed a new plasmid, pSEH-Flag-HBV, and transfected it into HepG2 cell.. Read More»
- Genet. Mol. Res. 11(2):
- 2012.May.18.3
- DOI:
- 10.4238/2012.May.18.3
A study on natural recovery of tassel fertilization and doubling method in maize haploids
Authors: L. Jiang, X.Y. Yang, X.Y. Li, P.K. Deng, G.X. Jing, X.Q. Wang,Z. Xing, R.G. Zhao
Doubling method is the technical barriers in maize haploid breeding. It was very important to establish the independent intellectual property rights for doubling method. In this experiment, the maize haploid inducer, TG15, was used for producing maternal haploids. Also, haploids were obtained from two kinds of maternal genotyp.. Read More»
- Genet. Mol. Res. 16(1):
- gmr16019173
- DOI:
- 10.4238/gmr16019173
Molecular cloning and mRNA expression of a hepcidin gene from the spinyhead croaker, Collichthys lucidus
Authors: C. Sang, Y. Lin, K. Jiang, F. Zhang, W. Song
Antimicrobial peptides are important components that participate in host innate immune activities and play crucial roles in host defense against microbial invasion. Hepcidin is an antimicrobial peptide and iron-regulatory molecule that primarily functions in the liver. In the present study, we first obtained a full-length cDNA.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.7.18
- DOI:
- 10.4238/2015.December.7.18
A snapshot on prokaryotic diversity of the Solim�µes River basin (Amazon, Brazil)
Authors: D. Toyama, C.D. Santos-J�ºnior, L.T. Kishi, T.C.S. Oliveira, J.W. Garcia, H. Sarmento, F.P. Miranda and F. Henrique-Silva
The Amazon region has the largest hydrographic basin on the planet and âÂ?¨is well known for its huge biodiversity of plants and animals. However, âÂ?¨there is a lack of studies on aquatic microbial biodiversity in the âÂ?¨Solimões River, one of its main water courses. To investigate the âÂ?¨microbial biodiversi.. Read More»
- Genet. Mol. Res. 16(2):
- gmr16029567
- DOI:
- 10.4238/gmr16029567
Effect of bradykinin on renal mesangial cell proliferation and extracellular matrix secretion
Authors: C.Y. Liu, L.L. Zhou, Q. Cheng, S.N. Jiang, J. Sheng, J.D. Sun and J.Y. Zhao
Recent studies have found that bradykinin (BK) plays a role in delaying glomerulosclerosis, although the mechanism of this phenomenon remains unclear. Mesangial cell proliferation (MCP) and extracellular matrix (ECM) secretion are important mechanisms for glomerulosclerosis. This study investigated the impact of BK on the plat.. Read More»
- Genet. Mol. Res. 13(1):
- http://dx.doi.org/2014.January.21.18
- DOI:
- http://dx.doi.org/10.4238/2014.January.21.18
Correlation of ERCC1 expression in peripheral blood lymphocytes with outcomes of patients with gastric cancer treated with oxaliplatin-based adjuvant chemotherapy
Authors: Y.Y. Zhang, K.S. Gu, H.Y. Wu,F. Yang, L.J. Bu, C.C. Zhao,Y.R. Zhang
Excision repair cross-complementing gene-1 (ERCC1) is a key regulatory enzyme whose expression patterns in tumor tissues are associated with survival in gastric cancer. The present study aimed to evaluate the effects of ERCC1 expression in peripheral blood lymphocytes (PBLs) on the outcome of patients with gastric cancer treat.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.7.3
- DOI:
- 10.4238/2015.December.7.3
Relationship between TLR4 and CCL2 expression and recurrent spontaneous abortion
Authors: P. Li1,2, H.L. Wu2 and B.H. Dong1
The increasing incidence of recurrent spontaneous abortion (RSA) severely affects women’s health. The involvement of the immune system during pregnancy and its contribution to RSA draw researchers’ attention. Both Toll-like receptor 4 (TLR4) and chemokine (C-C motif) ligand 2 (CCL2) have been linked to various pregnancy disorders. In this stud.. Read More»
- Genet. Mol. Res. 15(1):
- gmr.15016882
- DOI:
- 10.4238/gmr.15016882
Low prevalence of glucokinase gene mutations in gestational diabetic patients with good glycemic control
Authors: H.R. Frigeri, I.C.R. Santos, R.R. R�©a, A.C.R. Almeida, C.M.T. Fadel-Picheth, F.O. Pedrosa, E.M. Souza, F.G.M. Rego and G. Picheth
Glucokinase (GCK) plays a key role in glucose homeostasis. Gestational diabetes mellitus increases the risk of gestational complications in pregnant women and fetuses. We screened for mutations in coding and flanking regions of the GCK gene in pregnant women with or without gestational diabetes in a Brazilian population. A sam.. Read More»
- Genet. Mol. Res. 11(2):
- 2012.May.18.2
- DOI:
- 10.4238/2012.May.18.2
Genetic parameters and path analysis in cowpea genotypes grown in the Cerrado/Pantanal ecotone
Authors: K.V. Lopes, P.E. Teodoro, F.A. Silva, M.T. Silva, R.L. Fernandes,T.C. Rodrigues, T.C. Faria and A.M. Corr�ªa
Estimating genetic parameters in plant breeding allows us to know the population potential for selecting and designing strategies that can maximize the achievement of superior genotypes. The objective of this study was to evaluate the genetic potential of a population of 20 cowpea genotypes by estimating genetic parameters and.. Read More»
- Genet. Mol. Res. 16(2):
- gmr16029559
- DOI:
- 10.4238/gmr16029559