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Bioinformatics   Research Article

Evolutive and structural characterization of Nostoc commune iron-superoxide dismutase that is fit for modification

Authors: Y. Ma M. Lu J.-Y. Li Y. Qin X.-G. Gong

Superoxide dismutase (SOD) has extensive clinical applications for protecting organisms from toxic oxidation. In this study, the integrated iron-superoxide dismutase gene (fe-sod) coding sequence of Nostoc commune stain CHEN was cloned from genomic DNA and compared to sods from other reported algae. These analyses of immunology and phylogenetics indicated th.. Read More»

Genet. Mol. Res. 11(4):
2012.October.4.8
DOI:
10.4238/2012.October.4.8
Plant Genetics   Research Article

Myrciaria dubia, an Amazonian fruit: population structure and its implications for germplasm conservation and genetic improvement

Authors: C.F. Nunes, T.A. Setotaw, M. Pasqual, E.A. Chagas, E.G. Santos,D.N. Santos, C.G.B. Lima, G.M.A. Can�§ado

Myrciaria dubia (camu-camu) is an Amazon tree that produces a tart fruit with high vitamin C content. It is probably the fruit with the highest vitamin C content among all Brazilian fruit crops and it can be used to supplement daily vitamin C dose. This property has attracted the attention of consumers and, consequently, encou.. Read More»

Genet. Mol. Res. 16(1):
gmr16019409
DOI:
10.4238/gmr16019409
Human Genetics   Research Article

Prognostic role of microRNA-100 in patients with bladder cancer

Authors: Y.H. Cao, H.H. Zhang,H.F. Xu, Y.J. Duan, Q. Li, B. Huang

We investigated the clinical significance and prognostic value of microRNA-100 (miR-100) in bladder cancer. Quantitative real-time polymerase chain reaction was used to analyze the expression of miR-100 in 92 pairs of human bladder cancer and adjacent normal tissue samples. Overall survival (OS) curves were plotted using the K.. Read More»

Genet. Mol. Res. 14(4):
2015.December.7.6
DOI:
10.4238/2015.December.7.6
Animal Genetics   Research Article

Genotyping of SNPs associated with meat tenderness: comparison of two PCR-based methods

Authors: L.E. L�³pez-Rojas, L. Pati�±o-Cadavid, A. L�³pez-Herrera and J.J. Echeverri-Zuluaga

Single nucleotide polymorphisms (SNPs) carried in calpain (CAPN1), calpastatin (CAST), and leptin (LEP) genes are associated with meat tenderness. Due to the economic importance of this meat quality attribute, the development of fast, reliable, and affordable methods to identify bovine carriers of favorable alleles is of great.. Read More»

Genet. Mol. Res. 16(2):
gmr16029635
DOI:
10.4238/gmr16029635
Cytogenomics   Research Article

Association of p53 Arg72Pro and MDM2 SNP309 polymorphisms with glioma

Authors: J.N. Zhang S.H. Yi X.H. Zhang X.Y. Liu Q. Mao S.Q. Li W.H. Xiong Y.M. Qiu T. Chen J.W. Ge

Epidemiological studies of the association of variants p53 Arg72Pro and MDM2 single-nucleotide polymorphism 309 (SNP309) with glioma risk have produced inconsistent results. The aim of the current study was to evaluate the association of these 2 variants with glioma susceptibility using a meta-analysis approach. For p53 Arg72Pro, 10 case-control studies i.. Read More»

Genet. Mol. Res. 11(4):
2012.October.4.9
DOI:
10.4238/2012.October.4.9
Plant Genetics   Research Article

Phenotypic and molecular fingerprinting of fast growing rhizobia of field-grown pigeonpea from the eastern edge of the Brazilian Pantanal

Authors: F.M. Costa, J.A. Schiavo, M.S. Brasil, J. Leite, G.R. Xavier andP.I. Fernandes Jr

The aim of this study was to evaluate the diversity of rhizobial isolates obtained from root nodules of pigeonpea plants grown at the eastern edge of the Brazilian Pantanal. The bacterial isolates were isolated from root nodules from field-growing pigeonpea grown in two rural settlements of the Aquidauana municipality. The bac.. Read More»

Genet. Mol. Res. 13(1):
2014.January.21.16
DOI:
10.4238/2014.January.21.16
Plant Genetics   Research Article

Development of microsatellite loci for Taxus wallichiana var. wallichiana (Taxaceae) and cross-amplification in Taxaceae

Authors: B.B. Cheng, Q.W. Sun,Y.Q. Zheng

Nine polymorphic microsatellite loci were isolated and characterized in Taxus wallichiana var. wallichiana, an endangered species in China. The number of alleles per locus ranged from 2 to 20. Observed and expected heterozygosities varied from 0.0260 to 0.5325 and 0.3603 to 0.9231, respectively. Positive cross-amplification of.. Read More»

Genet. Mol. Res. 14(4):
2015.December.7.15
DOI:
10.4238/2015.December.7.15
Animal Genetics   Research Article

Effect of photoperiod on serum hormone concentrations during the annual reproductive cycle in geese

Authors: X.Z. Zhao, G.L. Gao, H.W. Wang, Q. Li, K.S. Zhang,H. Zhong, Q.G. Wang

The poor egg-laying rate of geese hinders the development of the goose industry; therefore, the reproductive performance of geese is an important area of investigation. To evaluate the relationship between photoperiod, reproductive hormones, and reproductive activity during the egg-laying cycle in geese under natural condition.. Read More»

Genet. Mol. Res. 16(1):
gmr16019266
DOI:
10.4238/gmr16019266
Human Genetics   Research Article

Genetic diversity of native populations of Croton tetradenius Baill. using ISSR markers

Authors: C.S. Almeida-Pereira, A.V.C. Silva, R.P. Alves, R.B. Feitosa-Alcantara, M.F. Arrigoni-Blank, S.V. Alvares-Carvalho, T.S. Costa, L.A.S. White, V.S. Pinto, T.S. Sampaio and A.F. Blank

Brazil has about 300 Croton species in different types of vegetation. Croton tetradenius Baill., which is endemic to the Northeast region and predominant in the Caatinga vegetation, stands out among the several species of this genus. Considering the importance of knowing the genetic variability of a species, the objective of t.. Read More»

Genet. Mol. Res. 16(2):
gmr16029602
DOI:
10.4238/gmr16029602
Human Genetics   Research Article

Copy number variations in spermatogenic failure patients with chromosomal abnormalities and unexplained azoospermia

Authors: Y. Dong, Y. Pan, R. Wang,Z. Zhang, Q. Xi,R.-Z. Liu

Male infertility is mostly caused by spermatogenic failure. Currently, routine genetic analyses of unexplained azoospermia or oligozoospermia are limited to the investigation of Y chromosomal microdeletions and chromosome karyotype analyses. The aim of this study was to find spermatogenic failure genes in patients with chromos.. Read More»

Genet. Mol. Res. 14(4):
2015.December.7.17
DOI:
10.4238/2015.December.7.17