Selecting elephant grass families and progenies to produce bioenergy through mixed models (REML/BLUP)
Authors: E.V. Rodrigues, R.F. Daher, A. dos Santos, M. Vivas, J.C. Machado, G. do A. Gravina, Y.P. de Souza, A.K. Vidal, A. dos S. Rocha and R.S. Freitas
Brazil has great potential to produce bioenergy since it is located in a tropical region that receives high incidence of solar energy and presents favorable climatic conditions for such purpose. However, the use of bioenergy in the country is below its productivity potential. The aim of the current study was to select full-sib.. Read More»
- Genet. Mol. Res. 16(2):
- gmr16029301
- DOI:
- 10.4238/gmr16029301
Detection of serum anti-melanocyte antibodies and identification of related antigens in patients with vitiligo
Authors: M.C. Zhu,C.G. Liu, D.X. Wang,Z. Zhan
We detected autoantibodies against melanocytes in serum samples obtained from 50 patients, including 4 with HBV, with vitiligo and identified the associated membrane antigens. Heat shock protein 70 (HSP70) and anti-tyrosinase-related protein 1 (TRP-1) antibody levels were analyzed. The associated antigens in normal human melan.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.7.19
- DOI:
- 10.4238/2015.December.7.19
Application of functional genomic information to develop efficient EST-SSRs for the chicken (Gallus gallus)
Authors: M.R. Bakhtiarizadeh, B. Arefnejad, E. Ebrahimie and M. Ebrahimi
Many years of domestication and breeding have given rise to the wide range of chicken breeds that exist today; however, an increasing number of local chicken breeds are under threat of extinction. A comprehensive characterization of chicken markers (especially type I markers) is needed to monitor and conserve genetic diversity.. Read More»
- Genet. Mol. Res. 11(2):
- dx.doi.org/2012.May.21.12
- DOI:
- dx.doi.org/10.4238/2012.May.21.12
Biological analysis of chronic lymphocytic leukemia: integration of mRNA and microRNA expression profiles
Authors: L. Dong1, K.H. Bi1, N. Huang1 and C.Y. Chen2
Chronic lymphocytic leukemia (CLL) is a disease that involves progressive accumulation of nonfunctioning lymphocytes and has a low cure rate. There is an urgent requirement to determine the molecular mechanism underlying this disease in order to improve the early diagnosis and treatment of CLL. In this study, genes differentially expressed between CLL sam.. Read More»
- Genet. Mol. Res. 15(1):
- gmr.15017170
- DOI:
- 10.4238/gmr.15017170
Association of tumor necrosis factor-�± 308G/A polymorphism with urogenital cancer risk: a systematic review and meta-analysis
Authors: J. Cai,M.Y. Yang, N. Hou, X. Li
We integrated all the eligible studies and investigated whether the TNF-α 308G/A polymorphism correlates with urogenital cancer risk. Tumor necrosis factor-α (TNF-α) is a risk factor for some urogenital cancers; however, in prostate and bladder cancers the results are controversial. PubMed, EMBASE, Web of Sci.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.7.22
- DOI:
- 10.4238/2015.December.7.22
Recombinant expression and characterization of an endoglucanase III (cel12a) from Trichoderma harzianum (Hypocreaceae) in the yeast Pichia pastoris
Authors: W.C. Generoso, W. Malag�³-Jr., N. Pereira Jr. and F. Henrique-Silva
Filamentous fungi from the genus Trichoderma have been widely investigated due to their considerable production of important biotechnological enzymes. Previous studies have demonstrated that the T. harzianum strain IOC-3844 has a high degree of cellulolytic activity. After excluding the native signal peptide, the open reading .. Read More»
- Genet. Mol. Res. 11(2):
- dx.doi.org/2012.May.21.11
- DOI:
- dx.doi.org/10.4238/2012.May.21.11
Association between adiponectin gene T45G polymorphism and nonalcoholic fatty liver disease risk: a meta-analysis
Authors: W. Zhang1, L.Q. Zhu1, X.L. Huo2, J. Qin2 and G.Y. Yuan3
Numerous epidemiological investigations have evaluated the association between adiponectin gene T45G polymorphism and risk of nonalcoholic fatty liver disease (NAFLD). However, the results of these studies have proven to be inconsistent. Therefore, we conducted a meta-analysis to obtain a more accurate estimation of this association. Published articles we.. Read More»
- Genet. Mol. Res. 15(1):
- gmr.15017190
- DOI:
- 10.4238/gmr.15017190
Detection of damage on single- or double-stranded DNA in a population exposed to arsenic in drinking water
Authors: J. JimÃ?©nez-Villarreal, D.I. Rivas-Armendariz, C.P. Pineda-Belmontes, N.D. Betancourt-MartÃ?Ânez, M.A. MacÃ?Âas-Corral, A.J. Guerra-Alanis, M.S NiÃ?±o-CastaÃ?±eda and J. MorÃ?¡n-MartÃ?Ânez
Different studies have suggested an association between arsenic (As) exposure and damage to single-stranded DNA by reactive oxygen species derived from the biotransformation of arsenic. The single strand damages are converted to double strand damage upon interaction with ultraviolet radiation. Analysis of genomic integrity is .. Read More»
- Genet. Mol. Res. 16(2):
- gmr16029241
- DOI:
- 10.4238/gmr16029241
MicroRNA-215 functions as a tumor suppressor and directly targets ZEB2 in human pancreatic cancer
Authors: Q.W. Li,T. Zhou, F. Wang,M. Jiang, C.B. Liu, K.R. Zhang, Q. Zhou, Z. Tian, K.W. Hu
It has been shown that microRNA-215 (miR-215) is dysregulated in several human malignancies, and this correlates with tumor progression. However, its expression and function in pancreatic cancer is still unclear. The aim of this study was to explore the effects of miR-215 on pancreatic cancer formation and progression. Using q.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.8.2
- DOI:
- 10.4238/2015.December.8.2
Africanized honey bees are efficient at detecting, uncapping and removing dead brood
Authors: M.M. Morais,T.M. Francoy,R.A. Pereira, D. De Jong, L.S. Gon�§alves
The hygienic behavior of honey bees is based on a two-step process, including uncapping and removing diseased, dead, damaged, or parasitized brood inside the cell. We evaluated during periods of 1 h the time that hygienic and non-hygienic colonies of Africanized honey bees spend to detect, uncap and remove pin-killed brood usi.. Read More»
- Genet. Mol. Res. 8(2):
- vol8-2kerr020
- DOI:
- 10.4238/vol8-2kerr020