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Animal Genetics   Research Article

Lipopolysaccharide and �²-1,3-glucan binding protein in the hard clam (Meretrix meretrix): Molecular characterization and expression analysis

Authors: S.X. Liu, Z.H. Qi, J.J. Zhang, C.B. He, X.G. Gao and H.J. Li

Pattern recognition molecules play an important role in innate immunity by recognizing conserved molecular patterns that are present on the surface of invading microorganisms. In this study, a lipopolysaccharide and β-1,3-glucan binding protein (LGBP) gene was cloned from the hard clam Meretrix meretrix .. Read More»

Genet. Mol. Res. 13(3):
2014.July.4.10
DOI:
10.4238/2014.July.4.10
Plant Genetics   Research Article

Genome-wide identification, phylogeny and expression analysis of the lipoxygenase gene family in cucumber

Authors: S.Q. Liu, X.H. Liu and L.W. Jiang

Plant lipoxygenase (LOX) is involved in growth and developmental control processes, through the biosynthesis of regulatory molecules and defense responses to pathogens, wounding and stress. To date, few LOX proteins and little tissue expression profiling have been reported in detail for cucumber (Cucumis sativus L.). Recent co.. Read More»

Genet. Mol. Res. 10(4):
2011.October.25.9
DOI:
10.4238/2011.October.25.9
Plant Genetics   Research Article

Combining abilities for agronomic traits and marker-assisted selection for Potato virus X and Potato virus Y resistance

Authors: M.L. Guedes, C.A.B.P. Pinto, G.H.M.R. Ribeiro, D.H. Lyra and O.L.G. Carneiro

Disease-resistant potato cultivars with good tuber appearance and desirable agronomic traits are essential for meeting the demands of producers and the market. Attaining these cultivars is the focus of potato breeding programs whose aim is to benefit the productive chain. The purpose of this study was to estimate combining abilities and evaluate potato cl.. Read More»

Genet. Mol. Res. 15(3):
gmr.15038685
DOI:
10.4238/gmr.15038685
Plant Genetics   Review Article

Functional characterization and signal transduction ability of nucleotide-binding site-leucine-rich repeat resistance genes in plants

Authors: R.K. Joshi and S. Nayak

Pathogen infection in plants is often limited by a multifaceted defense response triggered by resistance genes. The most prevalent class of resistance proteins includes those that contain a nucleotide-binding site-leucine-rich repeat (NBS-LRR) domain. Over the past 15 years, more than 50 novel NBS-LRR class resistance genes ha.. Read More»

Genet. Mol. Res. 10(4):
2011.October.25.10
DOI:
10.4238/2011.October.25.10
Human Genetics   Research Article

Detection of fetal RHD pseudogene (RHD�¨) and hybrid RHD-CE-Ds from RHD-negative pregnant women with a free DNA fetal kit

Authors: T. Gunel, I. Kalelioglu, A. Gedikbasi, H. Ermis and K. Aydinli

Hemolytic disease of the newborn is a clinical condition in which maternal and paternal Rh blood group antigens are incompatible and the mother is negative for the antigen whereas the father is positive. Analysis of fetal cells recovered from maternal plasma can provide a highly sensitive prenatal diagnosis. The fetal RHD gene.. Read More»

Genet. Mol. Res. 10(4):
2011.October.26.1
DOI:
10.4238/2011.October.26.1
Plant Genetics   Research Article

Isolation and characterization of genetic variability in bacteria with �²-hemolytic and antifungal activity isolated from the rhizosphere of Medicago truncatula plants

Authors: J.E. Hern�¡ndez-Salmer�³n, C.M. Prieto-Barajas, E. Valencia-Cantero, G. Moreno-Hagelsieb and G. Santoyo

In the present study, we analyzed the frequency of hemolytic and antifungal activities in bacterial isolates from the rhizosphere of Medicago truncatula plants. Of the 2000 bacterial colonies, 96 showed β-hemolytic activities (frequency, 4.8 x 10-2). Hemolytic isolates were analyzed for their genetic diversity by.. Read More»

Genet. Mol. Res. 13(3):
2014.July.4.11
DOI:
10.4238/2014.July.4.11
Animal Genetics   Research Article

Using PCR for early diagnosis of bovine leukemia virus infection in some native cattle

Authors: M.R. Mohammadabadi, M. Soflaei, H. Mostafavi and M. Honarmand

Bovine leukemia virus (BLV), the causative agent of enzootic bovine leukosis, is an exogenous, B lymphotropic retrovirus belonging to the Retroviridae family that induces persistent lymphocytosis in cattle and sheep. PCR has proven to be particularly suitable for investigating herds of cattle with a very low incidence of BLV i.. Read More»

Genet. Mol. Res. 10(4):
2011.October.27.2
DOI:
10.4238/2011.October.27.2
Animal Genetics   Research Article

Association of CD4 SNPs with fat percentage of Holstein cattle

Authors: T. Usman, Y. Yu, L. Zhai, C. Liu, X. Wang and Y. Wang

Cluster of differentiation 4 gene (CD4) is well known for its role in immunity, but its effects on production traits remain to be elucidated. The present study was designed to explore single nucleotide polymorphisms (SNPs) in the exons, flanking introns, and promoter of CD4, as well as to analyze their effects on milk production traits (percentage of prot.. Read More»

Genet. Mol. Res. 15(3):
gmr.15038697
DOI:
10.4238/gmr.15038697
Medical Genetics   Research Article

Hepatocyte growth factor upregulates nexilin gene expression in cardiomyocytes via JNK pathway

Authors: C. Wang, X. You, C. Jiang, C. Jin, X. Meng and D. Ding

Hepatocyte growth factor (HGF) is a protective factor in myocardial injury, but its mechanisms of action have not yet been fully elucidated. Nexilin, which locates specifically to the Z-disc, is a novel Z-disc protein that enables the Z-discs to persistently withstand the extreme mechanical forces generated during muscle contraction. Therefore, we investi.. Read More»

Genet. Mol. Res. 13(3):
2014.July.4.12
DOI:
10.4238/2014.July.4.12
Medical Genetics   Research Article

Distribution of HLA-B27 and CYP2D6*4 mutations in the middle Black Sea area (Tokat) of Turkey

Authors: S. Sahin, L. Aydogan, I. Benli and H. Ozyurt

We analyzed distribution of HLA-B27 and CYP2D6*4 mutations in 249 patients from Tokat province in Turkey with symptoms of arthritis, sacroiliac, joint and back pain, using a LightCycler 480 II Real-Time PCR thermal cycler. The Genes-4U was applied for studying HLA-B27 mutation, and the Tib-Molbiol commercial kit was used to ex.. Read More»

Genet. Mol. Res. 10(4):
2011.December.2.3
DOI:
10.4238/2011.December.2.3