Changes in expression of specific miRNAs and their target genes in repair of exercise-induced muscle injury in rats
Authors: W. Wu
The effects of muscle-specific miRNAs in the repair of exercise-induced muscle injury were investigated by examining the changes in their expression and that of the target genes in rat skeletal muscle. Two-month-old agile male rats were randomly divided into exercise and static control groups, the former subdivided into 0-h, 6-h, 12-h, 1-day, 2-day, 3-day.. Read More»
- Genet. Mol. Res. 15(3):
- gmr.15038698
- DOI:
- 10.4238/gmr.15038698
Genetic analysis of the major gene plus polygene model in soybean resistance to Leguminivora glycinivorella
Authors: J. Zhang, D. Yao, J. Ma, Y.-P. Fu, J. Qu and P.-W. Wang
In order to investigate the genetic characteristics of soybean Leguminivora glycinivorella resistance and to improve soybean resistance insectivorous breeding efficiency by applying the multi-generation joint analysis method of the major gene plus polygene model, 5 pedigrees and generations (P1, F1, P2, F2, and F2:3) .. Read More»
- Genet. Mol. Res. 13(3):
- 2014.July.4.13
- DOI:
- 10.4238/2014.July.4.13
Selection index using the graphical area applied to sugarcane breeding
Authors: L.A. Silva, R.T. Resende, R.A.D.C. Ferreira, G.N. Silv, V. Kist, M.H.P. Barbosa, M. Nascimento and L.L. Bhering
This study aimed to develop a multivariate selection index based on the graphical area of a polygon formed by standardized values, also known as radar chart. This methodology may be used to assist selection of superior genotypes in sugarcane breeding programs. Seven technological traits in 37 sugarcane genotypes were evaluated. An area index (AI) was cons.. Read More»
- Genet. Mol. Res. 15(3):
- gmr.15038711
- DOI:
- 10.4238/gmr.15038711
Association between miR-137 polymorphism and risk of schizophrenia: a meta-analysis
Authors: M.L. Ou, G. Liu, D. Xiao, B.H. Zhang, C.C. Guo, X.G. Ye, Y. Liu, N. Zhang, M. Wang, Y.J. Han, X.H. Ye, C.X. Jing and G. Yang
miR-137, a brain-enriched microRNA, is involved in the control of neuronal proliferation, differentiation, and dendritic arborization, all of which are important for proper neurogenesis and relevant to schizophrenia. miR-137 is also known to regulate many genes implicated in schizophrenia risk. Although reports have associated the miR-137 polymorphism rs1.. Read More»
- Genet. Mol. Res. 15(3):
- gmr.15038703
- DOI:
- 10.4238/gmr.15038703
Effect of codon optimization on expression levels of human cystatin C in Pichia pastoris
Authors: Y.M. Li, D.J. Li, X.J. Xu, M. Cui, H.H. Zhen and Q. Wang
Human cystatin C (CysC) is a cysteine proteinase inhibitor with many potential applications. To facilitate further studies of the functions and applications of CysC, we improved the heterologous expression of CysC using a basic codon optimization method. In this study, we cloned the high-GC content wild-type sequence of the .. Read More»
- Genet. Mol. Res. 13(3):
- 2014.July.4.14
- DOI:
- 10.4238/2014.July.4.14
Development of a transposon-based marker system for mutation breeding in sorghum (Sorghum bicolor L.)
Authors: S.B. Im, S.-J. Kwon, J. Ryu, S.W. Jeong, J.B. Kim, J.-W. Ahn, S.H. Kim, Y.D. Jo, H.-I. Choi and S.-Y. Kang
Under certain circumstances, transposable elements (TE) can create or reverse mutations and alter the genome size of a cell. Sorghum (Sorghum bicolor L.) is promising for plant transposon tagging due to its small genome size and its low content of repetitive DNA. We developed a marker system based on targeted region amplification polymorphisms (TE-TRAP) t.. Read More»
- Genet. Mol. Res. 15(3):
- gmr.15038713
- DOI:
- 10.4238/gmr.15038713
Influence of paeoniflorin on intracellular calcium ion concentration in the sphincter of Oddi of hypercholesterolemic rabbits
Authors: F. Wang, C.-M. Wang, J.-D. Liu and Y.-T. Wang
This study aimed to investigate the influence of hypercholesterolemia (HC) on intracellular calcium ion concentration in the sphincter of Oddi (SO) of rabbits and the influence of paeoniflorin on intracellular calcium ion concentration in the hypercholesterolemic rabbit SO. Sixteen purebred New Zealand rabbits were randomly di.. Read More»
- Genet. Mol. Res. 13(3):
- 2014.July.4.15
- DOI:
- 10.4238/2014.July.4.15
Morphological and molecular characterization of Cladosporium cladosporioides species complex causing pecan tree leaf spot
Authors: C. Walker, M.F.B. Muniz, J.M. Rolim, R.R.O. Martins, V.C. Rosenthal, C.G. Maciel, R. Mezzomo and L.R.S. Reiniger
The objective of this study was to characterize species of the Cladosporium cladosporioides complex isolated from pecan trees (Carya illinoinensis) with symptoms of leaf spot, based on morphological and molecular approaches. Morphological attributes were assessed using monosporic cultures on potato dextrose agar medium, which were examined for mycelial gr.. Read More»
- Genet. Mol. Res. 15(3):
- gmr.15038714
- DOI:
- 10.4238/gmr.15038714
Predictive role of vascular endothelial growth factor polymorphisms in the survival of renal cell carcinoma patients
Authors: Y.-Q. Yang and J. Chen
We conducted a study to investigate the possible role of the vascular endothelial growth factor (VEGF) polymorphisms -2578C/A, -1154G/A and -634C/G and clinical factors in renal cell carcinoma (RCC) prognosis in a cohort of 336 RCC cases. A total of 336 patients with RCC were recruited from PLA General Hospital between January.. Read More»
- Genet. Mol. Res. 13(3):
- 2014.July.4.16
- DOI:
- 10.4238/2014.July.4.16
Association between the CDH1-472delA and -160C>A polymorphisms and diffuse and intestinal gastric cancer in a Mexican population
Authors: A.R. Bustos-Carpinteyro, N. Delgado-Figueroa, E. Santiago-Luna, M.T. Maga�±a-Torres and J.Y. S�¡nchez-L�³pez
Gastric cancer (GC), the third leading cause of cancer-related deaths in Mexico and worldwide, can be classified into diffuse (DGC) or intestinal (IGC) types based on its histological characteristics. DGC is characterized by reduced expression of the cell adhesion protein E-cadherin, which is encoded by CDH1. The -472delA (rs5030625) and -160C>A (rs162.. Read More»
- Genet. Mol. Res. 15(3):
- gmr.15038715
- DOI:
- 10.4238/gmr.15038715