Antibody preparation and identification of the Cashmere goat c-kit protein in the testes
Authors: S.C.L. Wu, F.H. Luo*, Q.F. Kong and Y.J. Wu
The c-kit protein plays a major role in the regulation of germ cell development. Its expression and distribution in rodent testes have been widely reported. However, research regarding c-kit expression in domestic animals is scarce, and the expression pattern and distribution of c-kit in germ cells have not been clearly define.. Read More»
- Genet. Mol. Res. 13(3):
- 2014.July.2.13
- DOI:
- 10.4238/2014.July.2.13
Changes in methylation of genomic DNA from chicken immune organs in response to H5N1 influenza virus infection
Authors: Y.H. Zhang, J.L. Meng, Y. Gao, J.Y. Zhang, S.L. Niu, X.Z. Yu, Y.B. Li, Y.T. Guan, B.X. Sun and Z.H. Zhao
DNA methylation is an important epigenetic modification in eukaryotes, which plays a significant role in regulating gene expression. When the host is invaded by the influenza virus, gene expression is regulated via changes in DNA methylation levels or patterns, leading to the activation or suppression of relevant signaling pathways or networks, triggering.. Read More»
- Genet. Mol. Res. 15(3):
- gmr.15037382
- DOI:
- 10.4238/gmr.15037382
Intervention for prehypertension and its cardiovascular risk factors in Inner Mongolia
Authors: X.S. Zhao, R. Wang, L.R. Bin and S.Q.G. Wa
Blood pressure levels were evaluated among prehypertension patients with associated cardiovascular risk factors to determine the effect of different interventions with respect to new endpoint events. A total of 1112 patients were equally and randomly divided into control, lifestyle, drug, and lifestyle + drug groups, and were .. Read More»
- Genet. Mol. Res. 13(3):
- 2014.July.4.1
- DOI:
- 10.4238/2014.July.4.1
Detection of Salmonella Enteritidis in asymptomatic carrier animals: comparison of quantitative real-time PCR and bacteriological culture methods
Authors: B.M. Maciel, J.C.T. Dias, C.C. Romano, N. Sriranganathan, M. Brendel and R.P. Rezende
Quantification of Salmonella in asymptomatic carrier animals can be used to assess microbial risk and monitor the level of contamination in domestic animals used for food production. We examined the sensitivity, specificity and accuracy of real-time qPCR, without pre-enrichment or selective enrichment stages, for the quantific.. Read More»
- Genet. Mol. Res. 10(4):
- 2011.October.24.1
- DOI:
- 10.4238/2011.October.24.1
Interleukin-6 -572G/C polymorphism and prostate cancer susceptibility
Authors: W.J. Huan, L.J. Wu, Z.C. Min, L.T. Xu, C.M. Guo, Z.P. Chen, X.J. Lou, B. Xu3and B.D. Lv
Strong evidence suggests that cancer-associated inflammation promotes tumor growth and progression, and interleukin-6 (IL6) is an important modulator of inflammation. However, the roles of IL6 and mutations of its corresponding gene in prostate cancer have not been clearly documented. We retrieved data from the Oncomine database concerning IL6 expression .. Read More»
- Genet. Mol. Res. 15(3):
- gmr.15037563
- DOI:
- 10.4238/gmr.15037563
Isolation, identification, and antioxidant activity of polysaccharides from the shell of abalone (Haliotis discus hannai Ino)
Authors: Z.L. Wang, H.B. Liang, W. Guo, Z.F. Peng, J.D. Chen and Q.Q. Zhang
In this study, two antioxidative substances, a homogeneous polysaccharide [abalone shell polysaccharide (ASP-1), corresponding to the first peak by size exclusion chromatography] and a non-polysaccharide compound [abalone shell compound (ACS-2), corresponding to the second peak by size exclusion chromatography], were extracted.. Read More»
- Genet. Mol. Res. 13(3):
- 2014.July.4.2
- DOI:
- 10.4238/2014.July.4.2
Use of molecular markers in reciprocal recurrent selection of maize increases heterosis effects
Authors: A.P.C.G. Berilli, M.G. Pereira, L.S.A. Gon�§alves, K.S. da Cunha, H.C.C. Ramos, G.A. Souza Filho and A.T. do Amaral J�ºnior
We examined the effect of incorporation of molecular markers on variability between and within populations in order to maximize heterotic effects and longevity of a maize reciprocal recurrent selection program. Molecular variability was quantified by inter-simple sequence repeat (ISSR) markers between and within the maize popu.. Read More»
- Genet. Mol. Res. 10(4):
- 2011.October.25.6
- DOI:
- 10.4238/2011.October.25.6
Phylogenetic analysis of the Mongolian gerbil (Meriones unguiculatus) from China based on mitochondrial genome
Authors: C.L. Li, X.Y. Du, J. Gao, C. Wang, H.G. Guo, F.W. Dai, X.Y. Sa, W. An and Z.W. Chen
Meriones unguiculatus (Gerbillinae, Rodentia) is widely used as an animal model of human disease. Here, we provide the first report of the complete mitochondrial genome sequence of M. unguiculatus (GenBank accession Nos. KF425526 and NC_023263). The sequence contained the conserved vertebrate pattern of 13 protein-coding genes, 2 ribosomal RNAs, 22 transf.. Read More»
- Genet. Mol. Res. 15(3):
- gmr.15037703
- DOI:
- 10.4238/gmr.15037703
Association of chicken growth hormone polymorphisms with egg production
Authors: Y.J. Su, J.T. Shu, M. Zhang, X.Y. Zhang, Y.J. Shan, G.H. Li, J.M. Yin, W.T. Song, H.F. Li and G.P. Zhao
Growth hormone (GH) has diverse functions in animals, together with other hormones from the somatotropic axis. Here, chicken GH (cGH) was investigated in recessive white chickens and Qingyuan partridge chickens as a candidate gene affecting egg production traits. Chicken egg production traits were studied in association with 4.. Read More»
- Genet. Mol. Res. 13(3):
- 2014.July.4.3
- DOI:
- 10.4238/2014.July.4.3
A66G and C524T polymorphisms of the methionine synthase reductase gene are associated with congenital heart defects in the Chinese Han population
Authors: W. Zeng, L. Liu, Y. Tong, H.M. Liu, L. Dai and M. Mao
Congenital heart defects (CHDs) are the most common birth defects; genes involved in homocysteine/folate metabolism may play important roles in CHDs. Methionine synthase reductase (MTRR) is one of the key regulatory enzymes involved in the metabolic pathway of homocysteine. We investigated whether two polymorphisms (A66G and C.. Read More»
- Genet. Mol. Res. 10(4):
- 2011.October.25.7
- DOI:
- 10.4238/2011.October.25.7