Serum proteomic spectral characteristics of acute myeloid leukemia and their clinical significance
Authors: R.-J. Zheng, R.-J. Wu and X.-D. Ma
We investigated the differences between the serum proteomic spectral characteristics of acute myeloid leukemia (AML) patients and those of healthy people. We collected peripheral blood serum samples from 62 AML patients and 15 healthy controls. After removing high-abundance proteins, low-abundance serum proteins were separated.. Read More»
- Genet. Mol. Res. 16(2):
- gmr16029172
- DOI:
- 10.4238/gmr16029172
Identification of nutrient-dependent changes in extracellular pH and acid phosphatase secretion in Aspergillus nidulans
Authors: J.S. Freitas, E.M. Silva, A. Rossi
The present study was designed to identify nutrient-dependent changes in extracellular pH and acid phosphatase secretion in the biA1 palC4 mutant strain of Aspergillus nidulans. The palC4 mutant was selected as lacking alkaline phosphatase, but having substantially increased acid phosphatase activity when grown on solid minima.. Read More»
- Genet. Mol. Res. 6(3):
Effect of miRNA-203 on cervical cancer cells and its underlying mechanism
Authors: X.Z. Yin, D.M. Zhao, G.X. Zhang and L. Liu
miRNA-203 is involved in the development and progression of various types of cancer. However, its role in cervical cancer remains unclear. The aim of this study was to investigate the effect of miRNA-203 on the proliferation and migration of HeLa cervical cancer cells, as well as survivin expression in these cells. A miRNA-203 primer probe was designed ac.. Read More»
- Genet. Mol. Res. 15(3):
- gmr.15038680
- DOI:
- 10.4238/gmr.15038680
Genetic diversity of Bromeliaceae species from the Atlantic Forest
Authors: Y. Sheu, A.S. Cunha-Machado, A.B.P.L. Gontijo, F.C. Favoreto,T.C.B. Soares and F.D. Miranda
The Bromeliaceae family includes a range of species used for many purposes, including ornamental use and use as food, medicine, feed, and fiber. The state of Espírito Santo, Brazil is a center of diversity for this family in the Atlantic Forest. We evaluated the genetic diversity of five populations of the Bromeliaceae .. Read More»
- Genet. Mol. Res. 16(2):
- gmr16029636
- DOI:
- 10.4238/gmr16029636
Quaternary origin and genetic divergence of the endemic cactus Mammillaria pectinifera in a changing landscape in the Tehuac�¡n Valley, Mexico
Authors: A. Cornejo-Romero, J. Medina-S�¡nchez, T. Hern�¡ndez-Hern�¡ndez,B. Rend�³n-Aguilar, P.L. Valverde, A. Zavala-Hurtado,S.P. Rivas-Arancibia, M.A. P�©rez-Hern�¡ndez, G. L�³pez-Ortega,C. Jim�©nez-Sierra and C.F. Vargas-Mendoza
The endemic Mexican cactus, Mammillaria pectinifera, shows low dispersal capabilities and isolated populations within the highly dissected landscape of Tehuacán Valley. These characteristics can restrict gene flow and act upon the genetic divergence and speciation in aridplants. We conducted a phylogeographic study to d.. Read More»
- Genet. Mol. Res. 13(1):
- 2014.January.8.6
- DOI:
- 10.4238/2014.January.8.6
Differential characterization of holocentric chromosomes in triatomines (Heteroptera, Triatominae) using different staining techniques and fluorescent in situ hybridization
Authors: A. Morielle-Souza, M.T.V. Azeredo-Oliveira
A comparative study of holocentric chromosomes in the triatomine species Panstrongylus megistus, Rhodnius pallescens and Triatoma infestans was carried out in order to characterize heterochromatin, rDNA active sites and nucleolar proteins. Cytological preparations of seminiferous tubules were stained by silver impregnation, C .. Read More»
- Genet. Mol. Res. 6(3):
Toxoplasma gondii rhoptry protein 38 gene: sequence variation among isolates from different hosts and geographical locations
Authors: Y. Xu, N.Z. Zhang, J. Chen, G.H. Liu, Q.M. Xu, D.H. Zhou and X.Q. Zhu
Toxoplasma gondii is an obligate intracellular parasite that is able to infect almost all mammalian species, and may lead to toxoplasmosis of the host. In the present study, we examined sequence variation in rhoptry protein 38 (ROP38) genes among T. gondii isolates collected from different hosts and geographi.. Read More»
- Genet. Mol. Res. 13(3):
- 2014.January.14.3
- DOI:
- 10.4238/2014.January.14.3
A novel method for identifying SNP disease association based on maximal information coefficient
Authors: H.M. Liu, N. Rao, D. Yang, L. Yang, Y. Li and F. Ou
To improve single-nucleotide polymorphism (SNP) association studies, we developed a method referred to as maximal information coefficient (MIC)-based SNP searching (MICSNPs) by employing a novel statistical approach known as the MIC to identify SNP disease associations. MIC values varied with minor allele frequencies of SNPs and the odds ratios for diseas.. Read More»
- Genet. Mol. Res. 13(4):
- 2014.December.19.7
- DOI:
- 10.4238/2014.December.19.7
Molecular identification of cetaceans from the West Atlantic using the E3-I5 region of COI
Authors: L.H.O. Falc�£o, A.S. Campos, J.E.P. Freitas, M.A.A. Furtado-Neto and V.V. Faria
Molecular identification is very useful in cases where morphology-based species identification is not possible. Examples for its application in cetaceans include the identification of carcasses of stranded animals in advanced state of decomposition and body parts that are illegally traded. One DNA region that is often used for.. Read More»
- Genet. Mol. Res. 16(2):
- gmr16029607
- DOI:
- 10.4238/gmr16029607
Evidence of genetic tolerance to low availability of phosphorus in the soil among genotypes of Coffea canephora
Authors: L.D. Martins, W.N. Rodrigues, L.S. Machado, S.V.B. Brinate, T.V. Colodetti, J.F.T. Amaral and M.A. Tomaz
The expansion of agriculture to new areas in order to increase the competitiveness of coffee producing countries has resulted in cultivation expanding into regions with lower natural fertility. This scenario has created the need to differentiate genotypes of Conilon coffee based on their tolerance to low levels of nutrients in the soil, especially phospho.. Read More»
- Genet. Mol. Res. 14(3):
- http://dx.doi.org/2015.September.8.19
- DOI:
- http://dx.doi.org/10.4238/2015.September.8.19