Detecting circulating tumor cells in patients with advanced non-small cell lung cancer
Authors: Y.H. Xu, J. Zhou and X.F. Pan
We explored the expression and clinical significance of circulating tumor cells (CTCs) in patients with advanced non-small cell lung cancer (NSCLC). Sixty-six patients with advanced NSCLC at the Oncology Department of Jinzhou Hospital were selected as an observation group between February and December 2013. Healthy volunteers and 20 benign lung disease pa.. Read More»
- Genet. Mol. Res. 14(3):
- http://dx.doi.org/2015.September.1.1
- DOI:
- http://dx.doi.org/10.4238/2015.September.1.1
Genetic diversity of yacon accessions using ISSR markers
Authors: R.M. Lorenzoni, F. Menine, E. Marques J�ºnior, F.L. Oliveira and T.C.B. Soares
Yacon cultivation has been intensified and the investigations of this crop have increased at the scientific, agricultural, and social levels because the roots of yacon show beneficial properties for human health, such as reducing cholesterol and glucose blood levels. Since the investigations involving yacon are very recent, th.. Read More»
- Genet. Mol. Res. 16(2):
- gmr16029576
- DOI:
- 10.4238/gmr16029576
Impact of BMMSCs from different sources on proliferation of CD34+ cells
Authors: R.F. Liu, J.Q. Li, R.X. Hou, R. Wang and K.M. Zhang
There are significant differences on the biological characteristics of bone marrow mesenchymal stem cells (BMMSCs), immunological response, and antigen-presenting functions between patients with psoriasis and normal subjects, but there are no significant differences in aborted fetuses. We examined the differences in BMMSCs between aborted fetuses and patient.. Read More»
- Genet. Mol. Res. 14(1):
- 2015.January.23.22
- DOI:
- 10.4238/2015.January.23.22
Selection of morphoagronomic descriptors for the characterization of accessions of cassava of the Eastern Brazilian Amazon
Authors: R.S. Silva, E.F. Moura, J.T. Farias-Neto, C.A.S. Ledo and J.E. Sampaio
The aim of this study was to select morphoagronomic descriptors to characterize cassava accessions representative of Eastern Brazilian Amazonia. It was characterized 262 accessions using 21 qualitative descriptors. The multiple-correspondence analysis (MCA) technique was applied using the criteria: contribution of the descript.. Read More»
- Genet. Mol. Res. 16(2):
- gmr16029595
- DOI:
- 10.4238/gmr16029595
Characterization of a protein-protein interaction network of the CBL-interacting protein kinase 8 from sugarcane
Authors: T.F. Farani, A. Gentile, R.G. Tavares, C. Ribeiro and M. Menossi
Plants are sessile organisms and have evolved to tolerate a constantly changing environment. After the onset of different stress conditions, calcineurin B-like (CBL) proteins can sense calcium signals and activate CBL-interacting protein kinase (CIPK) proteins, which can phosphorylate downstream proteins to reestablish plant homeostasis. Previous studies .. Read More»
- Genet. Mol. Res. 14(1):
- 2015.January.26.1
- DOI:
- 10.4238/2015.January.26.1
Genetic structure of natural populations of Theobroma in the Juruena National Park, Mato Grosso State, Brazil
Authors: B.M. Silva, A.A.B. Rossi, J.F.E. Dardengo, C.R. Silva, I.V. Silva, M.L. Silva and C.J. Silva
Several species within the genus Theobroma have particularly high economic value, including T. cacao and T. grandiflorum. Other species in this genus, such as T. speciosum and T. subincanum, have potential value for use in the conservation of genetic diversity in breeding programs. These latter species could also be domesticated or improved to produce com.. Read More»
- Genet. Mol. Res. 14(3):
- http://dx.doi.org/2015.September.1.3
- DOI:
- http://dx.doi.org/10.4238/2015.September.1.3
Canonical correlations between agronomic traits and seed physiological quality in segregating soybean populations
Authors: E.M. Pereira, F.M. Silva, B.H.P. Val, A. Pizolato Neto, A.O. Mauro,C.C. Martins and S.H. Un�ªda-Trevisoli
The objective of this study was to evaluate the relationship between agronomic traits and physiological traits of seeds in segregating soybean populations by canonical correlation analysis. Seven populations and two commercial cultivars in three generations were used: F3 plants and F4 seeds; F4 plants and F5 seeds, and F4 seed.. Read More»
- Genet. Mol. Res. 16(2):
- gmr16029547
- DOI:
- 10.4238/gmr16029547
Biotools: an R function to predict spatial gene diversity via an individual-based approach
Authors: A.R. da Silva, G. Malafaia and I.P.P. Menezes
The gene diversity or expected heterozygosity (HE) is based on the allele frequency and is often used as a measure of genetic variability of populations. Knowing the pattern of spatial distribution of HE can be useful for determining strategies of conservation and sampling of collections of individuals. In addition, it can all.. Read More»
- Genet. Mol. Res. 16(2):
- gmr16029655
- DOI:
- 10.4238/gmr16029655
Development of TRAP primers for Ricinus communis L.
Authors: K.S. Sim�µes, S.A. Silva, E.L. Machado and H.S. Brasileiro
The objective of this article was to develop TRAP (target region amplification polymorphism) primers for castor bean, with the goal of making functional markers available for genetic studies about the species. To do this, oligonucleotides were designed based on ESTs, obtained from the NCBI (National Center for Biotechnology In.. Read More»
- Genet. Mol. Res. 16(2):
- gmr16029647
- DOI:
- 10.4238/gmr16029647
Roles of the AIB1 protein in the proliferation and transformation of human esophageal squamous cell carcinoma
Authors: L. Li, P. Wei, M.-H. Zhang, W. Zhang, Y. Ma, X. Fang, C.-L. Hao and Z.-H. Zhang
The aim of this study was to investigate the expression of AIB1 in human esophageal squamous cell carcinoma and its correlation with Ki67 expression. The immunohistochemical method streptavidin-perosidase was used to analyze the expression of AIB1 and Ki67 in specimens from 60 patients with esophageal squamous cell carcinoma and in 20 control individuals .. Read More»
- Genet. Mol. Res. 14(3):
- http://dx.doi.org/2015.September.1.4
- DOI:
- http://dx.doi.org/10.4238/2015.September.1.4