Development of a polymorphic short tandem repeat locus multiplex system for efficient human identification
Authors: R.G. Rodovalho, E.L. Rodrigues, G.S. Santos, L.M. Cavalcanti,P.R. Lima, A.G. Rodovalho, R.G. Vital, M.A.D. Gigonzac and A.D. da Cruz
This study aimed to develop a short tandem repeat (STR) multiplex system, made up of 22 highly informative STR loci, for application in forensic genetics. The system comprised 21 polymorphic autosomal loci (D3S1358, TH01, D21S11, D18S51, Penta E, D5S818, D13S317, D7S820, D16S539, CSF1PO, Penta D, vWA, D8S1179, TPOX, FGA, D2S44.. Read More»
- Genet. Mol. Res. 16(2):
- gmr16029557
- DOI:
- 10.4238/gmr16029557
Estimation of genetic distance between 10 maize accessions with varying response to different levels of soil moisture
Authors: M. Aslam, F.S. Awan, I.A. Khan and A.I. Khan
Ten maize accessions (NC-9, A50-2, M-14, B-42, NC-3, T-7, N-48-1, B-34, USSR, and WFTMS) were studied to estimate the genetic distance on molecular level by random amplified polymorphic DNA. These accessions were selected on the basis of their variable responses against different levels of moisture. Twenty-five primers were us.. Read More»
- Genet. Mol. Res. 8(4):
- vol8-4gmr606
- DOI:
- 10.4238/vol8-4gmr606
Association between TNF-�±rs1799724 and rs1800629 polymorphisms and the risk of Crohnâ��s disease
Authors: Y.Q. Mao, S.Q. Dong, M. Gao
We investigated the associations between 2 major tumor necrosis factor-α (TNF-α) polymorphisms, rs1799724 C>T and rs1800629 G>A, and the susceptibility to Crohn’s disease (CD) using a meta-analysis framework. The PubMed, EBSCO, Ovid, Wiley, Web of Science, WANFANG, and VIP databases (last updated search.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.1.33
- DOI:
- 10.4238/2015.December.1.33
RNA-binding motif protein RBM22 is required for normal development of zebrafish embryos
Authors: F. He, C.-T. Wang and L.-T. Gou
RBM22 is a newly discovered RNA-binding motif protein, belonging to the SLT11 family; it has been reported to be involved in pre-splicesome assembly and to interact with the Ca2+-signaling protein ALG-2. However, previous studies have not demonstrated whether its expression is essential for early embryogenesis in vertebrates. .. Read More»
- Genet. Mol. Res. 8(4):
- vol8-4gmr683
- DOI:
- 10.4238/vol8-4gmr683
A meta-analysis to evaluate the effectiveness of real-time PCR for diagnosing novel coronavirus infections
Authors: C. Lin,R. Ye, Y.L. Xia
Novel coronavirus (nCoV) belongs to the Coronaviridae family, which includes the virus that causes SARS, or severe acute respiratory syndrome. However, infection source, transmission route, and host of nCoV have not yet been thoroughly characterized. In some cases, nCoV presented a limited person-to-person transmission. Theref.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.1.15
- DOI:
- 10.4238/2015.December.1.15
RNA applications for endophytic research
Authors: J.C. Polonio, A.D. Polli, J.L. Azevedo and J.A. Pamphile
Endophytic microorganisms, mainly bacteria and fungi, have intrinsic relationships with the host plants, involving complex chemical and genetic communication networks. The relationship among these organisms involves the development of regulatory mechanisms of gene expression that control their development and response to different interactions. Although R.. Read More»
- Genet. Mol. Res. 15(3):
- gmr.15038879
- DOI:
- 10.4238/gmr.15038879
XRCC1 polymorphisms and haplotypes in Mexican patients with acute lymphoblastic leukemia
Authors: J.P. Meza-Espinoza, V. Peralta-Leal, M. Gutierrez-Angulo,N. Macias-Gomez, M.L. Ayala-Madrigal, P. Barros-Nu�±ez,J. Duran-Gonzalez and E. Leal-Ugarte
We examined the influence of the Arg194Trp, Arg280His, and Arg399Gln polymorphisms of XRCC1 (X-ray repair cross-complementing group 1) on the development of childhood acute lymphoblastic leukemia (ALL) in 120 ALL patients and 120 controls in Mexico. All of them were genotyped for these polymorphisms, using polymerase chain rea.. Read More»
- Genet. Mol. Res. 8(4):
- vol8-4gmr687
- DOI:
- 10.4238/vol8-4gmr687
Molecular phylogeny of the Bactrian camel based on mitochondrial Cytochrome b gene sequences
Authors: L. Ming, L. Yi, FC. Guo, S. Siriguleng and J. Jirimutu
The Bactrian camel is an important domesticated animal providing milk, meat, and other products in desert countries. In this study, 111 individuals representing 11 domestic Bactrian camel breeds from China, Mongolia, Russia, and one wild Bactrian camel group from Mongolia were selected for the preparation of mitochondrial DNA. The 1140-bp fragments of the.. Read More»
- Genet. Mol. Res. 15(3):
- gmr.15038983
- DOI:
- 10.4238/gmr.15038983
Influence of suppression of CapG gene expression by siRNA on the growth and metastasis of human prostate cancer cells
Authors: B.K. Li, K. Guo, C.Y. Li, H.L. Li, P.P. Zhao,K. Chen,C.X. Liu
This study investigated CapG gene expression in prostate cancer cell lines; in addition, we explored the effects of CapG suppression on DU145 cell growth, and the underlying mechanism with which CapG affects DU145 cell growth and invasiveness. The expression of CapG and 18 related genes in DU145 cells was analyzed by flow cyto.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.1.28
- DOI:
- 10.4238/2015.December.1.28
Meiotic behavior of a nonaploid accession endorses x = 6 for Brachiaria humidicola (Poaceae)
Authors: K.R. Boldrini, M.S. Pagliarini and C.B. Valle
Brachiaria humidicola (Poaceae), originally from Africa, is an economically important pasture plant in tropical South America. An accession of B. humidicola (H038) collected from the wild African savanna (Mbeya, Tanzania) showed irregular microsporogenesis. This meiotic behavior was consistent with an allopolyploid origin. Mul.. Read More»
- Genet. Mol. Res. 8(4):
- vol8-4gmr679
- DOI:
- 10.4238/vol8-4gmr679