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Human Genetics   Research Article

Cathecol-O-methyl transferase Val158Met genotype is not a risk factor for conversion disorder

Authors: E. Armagan M.L. Almac�±oglu T. Yakut A. K�¶se M. Karkucak O. K�¶ksal O. Gorukmez

Alterations in catechol-O-methyltransferase (COMT) activity are involved in various types of neurological disorders. We examined a possible association between the COMT Val158Met polymorphism and conversion disorder in a study of 48 patients with conversion disorder and 48 control patients. In the conversion disorder group, 31 patients were Val/Met hetero.. Read More»

Genet. Mol. Res. 12(1):
2013.March.19.1
DOI:
10.4238/2013.March.19.1
Microbial Genetics   Research Article

Genome-wide partial correlation analysis of Escherichia coli microarray data

Authors: Veiga DFT, Vicente FFR, Grivet M, de la Fuente A and Vasconcelos ATR

Transcriptional control is an essential regulatory mechanism employed by bacteria. Much about transcriptional regulation remains to be discovered, even for the most widely studied bacterium, Escherichia coli. In the present study, we made a genome-wide loworder partial correlation analysis of E. coli microarray data with the p.. Read More»

Genet. Mol. Res. 6(4):
Human Genetics   Research Article

Genetic diversity and population structure in Brazilian Mangalarga Marchador horses

Authors: J.B. DeAssis, D.M. DeLaat, M.G.C.D. Peixoto, J.A.G. Bergmann,C.G. Fonseca and M.R.S. Carvalho

One hundred and fifteen unrelated Mangalarga Marchador horses were sampled from three geographically distinct regions of Minas Gerais State, Brazil (South, Southeast, and Northeast) and tested for 10 microsatellite loci. Genetic diversity and population structure parameters were estimated with ARLEQUIN 3.0, CERVUS 2.0, POPGENE.. Read More»

Genet. Mol. Res. 8(4):
vol8-4gmr647
DOI:
10.4238/vol8-4gmr647
Human Genetics   Research Article

Combined detection of p53, p16, Rb, and EGFR mutations in lung cancer by suspension microarray

Authors: Y. Ye, D. Wang, C. Su, T. Rong and A. Guo

Mutations of some contributing factors (p53, p16, Rb, and EGFR) are believed to affect diagnosis and drug resistance of lung cancer. We evaluated the efficacy of a multimarker panel for molecular diagnosis of lung cancer, using a high-throughput suspension microarray. One hundred and twenty-five lung cancer specimens and 30 tu.. Read More»

Genet. Mol. Res. 8(4):
vol8-4gmr627
DOI:
10.4238/vol8-4gmr627
Plant Genetics   Research Article

Cytogenetic comparison of tree frogs of the genus Aplastodiscus and the Hypsiboas faber group (Anura, Hylidae)

Authors: K.A. Carvalho, P.C.A. Garcia and S.M. Recco-Pimentel

Four species of Aplastodiscus and two species of Hypsiboas were cytogenetically compared. Aplastodiscus perviridis, A. cochranae, H. albomarginaus, and H. faber had 2n = 24 chromosomes, while A. albosignatus and A. leucopygius had 2n = 20 and 2n = 18 chromosomes, respectively. Aplastodiscus perviridis and A. cochranae had iden.. Read More»

Genet. Mol. Res. 8(4):
vol8-4gmr697
DOI:
10.4238/vol8-4gmr697
Plant Genetics   Research Article

New set of microsatellites for Chinese tallow tree, Triadica sebifera

Authors: Y.F. Zhuang, Z.F. Wang and L.F. Wu

Chinese tallow (Triadica sebifera) is an important crop and ornamental tree. After it was introduced into the USA, it gradually became a noxious invasive tree in south-eastern America since the middle of the 1900s. Because only six microsatellites were reported previously in T. sebifera, to better understand the genetic divers.. Read More»

Genet. Mol. Res. 16(2):
gmr16029624
DOI:
10.4238/gmr16029624
Animal Genetics   Research Article

Brazilian strain of bovine respiratory coronavirus is derived from dual enteric and respiratory tropism

Authors: E.A. Beuttemmuller, A.F. Alfieri, S.A. Headley and A.A. Alfieri

Bovine coronavirus (BCoV) is a pathogen related to enteric and respiratory diseases in cattle worldwide. Enteric (BECoV) strains of BCoV are predominant in South America, and genetic investigations have been conducted to identify its relationship with isolates of respiratory origin (BRCoV). In this study, we used a BRCoV strai.. Read More»

Genet. Mol. Res. 16(2):
gmr16029580
DOI:
10.4238/gmr16029580
Human Genetics   Research Article

Dietary carotenoid-rich pequi oil reduces plasma lipid peroxidation and DNA damage in runners and evidence for an association with MnSOD genetic variant -Val9Ala

Authors: A.L. Miranda-Vilela, A.K. Akimoto, P.C.Z. Alves, L.C.S. Pereira,C.A. Gon�§alves, M.N. Klautau-Guimar�£es and C.K. Grisolia

Physical training induces beneficial adaptations; however, exhausting exercise increases reactive oxygen species generation, resulting in damage to DNA and tissues. Pequi (Caryocar brasiliense), a fruit of the Brazilian Cerrado, contains a carotenoid-rich oil. We investigated whether pequi oil had antioxidant effects in runner.. Read More»

Genet. Mol. Res. 8(4):
Plant Genetics   Research Article

New sources of resistance to leafminers (Liriomyza sativae) in melon (Cucumis melo L.) germplasm

Authors: E.F. Celin, F.I.C. Oliveira, N.S. Dias-Pini, G.H.S. Nunes and F.A.S. Arag�£o

Leafminers (Liriomyza sativae) are the main melon (Cucumis melo L.) pests in Northeast Brazil, which is the main region for the production and export of the fruit in Brazil. Of the integrated management strategies available, genetic resistance is the best method of preventing damage by these insects. The aim of this study was .. Read More»

Genet. Mol. Res. 16(2):
gmr16029561
DOI:
10.4238/gmr16029561
Human Genetics   Research Article

Simultaneous presence of bovine papillomavirus in blood and in short-term lymphocyte cultures from dairy cattle in Pernambuco, Brazil

Authors: N. Diniz, T.C. Melo, J.F. Santos, E. Mori, P.E. Brand�£o, L.J. Richtzenhain, A.C. Freitas, W. Be�§ak, R.F. Carvalho and R.C. Stocco

Bovine papillomaviruses (BPV) are the causal agents of benign and malignant lesions; they can cause dramatic economic losses in cattle. Although 10 virus types have been described, three types are most common in tumors, namely BPV-1, -2 and -4. Previous studies have reported BPV in blood cells and the possibility of blood acti.. Read More»

Genet. Mol. Res. 8(4):
vol8-4gmr668
DOI:
10.4238/vol8-4gmr668