Monosomy 1p36 syndrome: reviewing the correlation between deletion sizes and phenotypes
Authors: C.F. Rocha1, R.B. Vasques2, S.R. Santos1 and C.L.A. Paiva1,3
The major clinical features of monosomy 1p36 deletion are developmental delay and hypotonia associated with short stature and craniofacial dysmorphisms. The objective of this study was to review the cases of 1p36 deletion that was reported between 1999 and 2014, in order to identify a possible correlation between the size of the 1p36-deleted segment and t.. Read More»
- Genet. Mol. Res. 15(1):
- gmr.15017942
- DOI:
- 10.4238/gmr.15017942
Genetic variability of watermelon accessions based on microsatellite markers
Authors: R.N.C. de S. Gama C.A.F. Santos R. de C.S. Dias
We analyzed the genetic variability of 40 watermelon accessions collected from 8 regions of Northeastern Brazil using microsatellite markers, in order to suggest strategies of conservation and utilization of genetic variability in this species. These accessions are not commercial cultivars. They were sampled in areas of traditional farmers that usually keep .. Read More»
- Genet. Mol. Res. 12(1):
- 2013.March.13.3
- DOI:
- 10.4238/2013.March.13.3
A framework for modeling of juxtacrine signaling systems
Authors: Rozante LCS, Gubitoso MD and Matioli SR
Juxtacrine signaling is intercellular communication, in which the receptor of the signal (typically a protein) as well as the ligand (also typically a protein, responsible for the activation of the receptor) are anchored in the plasma membranes, so that in this type of signaling the activation of the receptor depends on direct.. Read More»
- Genet. Mol. Res. 6(4):
Prevalence of thymidylate synthase gene 5'-untranslated region variants in an Argentinean sample
Authors: C. VÃ?¡zquez, M. Orlova, P. Scibona, H. DÃ?Âaz Arce, M.G. Pallotta and W.H. Belloso
Thymidylate synthase (TYMS) is a key enzyme in nucleotide synthesis and therefore, an important target of many chemotherapeutic agents. Expression of TYMS mRNA is thought to be modulated by a 28-bp tandem repeat polymorphism within its 5'-untranslated region, raising the question of this variant’s utility in predicting t.. Read More»
- Genet. Mol. Res. 16(1):
- gmr16019367
- DOI:
- 10.4238/gmr16019367
Production of interspecific hybrids between commercial cultivars of the eggplant (Solanum melongena L.) and its wild relative S. torvum
Authors: J. Kumchai Y.-C. Wei C.-Y. Lee F.-C. Chen S.-W. Chin
Interspecific hybrids between cultivars of eggplant (Solanum melongena L.) and its wild relative S. torvum, which has disease resistance and desirable traits for crop improvement, were obtained by cross-hybridization and embryo rescue. Twenty-one hybrid progenies were obtained and examined based on morphological traits, RAPD and ISSR markers. Five of them.. Read More»
- Genet. Mol. Res. 12(1):
- 2013.March.13.4
- DOI:
- 10.4238/2013.March.13.4
Phylogeny of Marmosops and the occurrence of Marmosops pinheiroi (Pine, 1981) (Didelphimorphia, Didelphidae) in the Cerrado savanna of Maranh�£o, Brazil
Authors: D.C. Nascimento, A.P.M. OlÃ?Âmpio, E. ConceiÃ?§Ã?£o, B.A.T.P. Campos, E.C. Fraga and M.C. Barros
The present study reviews the phylogeny of the genus Marmosops and expands the geographic range of Marmosops pinheiroi to the Brazilian State of Maranhão. Five specimens of M. pinheiroi were collected from the Inhamum Municipal Environmental Protection Area in Caxias, Maranhão. Total DNA was extracted and the mitochondrial cytochrome b gene .. Read More»
- Genet. Mol. Res. 14(1):
- 2015.January.23.4
- DOI:
- 10.4238/2015.January.23.4
Differential expression of the lethal gene Luteus-Pa in cacao of the Parinari series
Authors: B.C. Rehem1, A.-A.F. Almeida1, G.S.F. Figueiredo1, A.S. Gesteira2, S.C. Santos1, R.X. Corr�ªa1, M.M. Yamada3 and R.R. Valle3
The recessive lethal character Luteus-Pa is found in cacao (Theobroma cacao) genotypes of the Parinari series (Pa) and is characterized by expression of leaf chlorosis and seedling death. Several genotypes of the Pa series are bearers of the gene responsible for the expression of the Luteus-Pa character, which can be used as a tool for determining relatio.. Read More»
- Genet. Mol. Res. 15(1):
- gmr.15014925
- DOI:
- 10.4238/gmr.15014925
Serum lipid abnormalities are not associated with apoB 3' VNTR polymorphism in nephrotic children
Authors: P. Hu B. Hu Y.H. Qin L. Lu Z.Q. Li L.Q. Tao Q. Pei J. Chen
Apolipoprotein B (apoB) gene 3' variable number of tandem repeat (VNTR) is highly variable, and therefore can be an informative marker for associative analysis of lipid metabolism. This is the first report focusing on a possible association of apoB VNTR polymorphism with nephrotic hyperlipidemia. Genomic DNA was extracted from 500 children with primary nephr.. Read More»
- Genet. Mol. Res. 12(1):
- 2013.March.13.5
- DOI:
- 10.4238/2013.March.13.5
Application value of multislice spiral computed tomography angiography in the evaluation of renal artery variation in living donor kidney transplantation
Authors: X.Y. Zhao, J. Tian, Y.H. Ru, B. Sun, C.F. Sun, A.M. Zhang and Y.H. Shao
This study aims to investigate the accuracy and value of multislice spiral computed tomography (MSCT) angiography in the evaluation of renal artery variation in living donor kidney transplantation. Two hundred seventy-three kidney transplantation donors underwent preoperative MSCT scanning. Two doctors determined the running direction and variation of the re.. Read More»
- Genet. Mol. Res. 14(1):
- 2015.January.23.5
- DOI:
- 10.4238/2015.January.23.5
On the characterization of energy networks of proteins
Authors: Veloso CJM, Silveira CH, Melo RC, Ribeiro C, Lopes JCD, Santoro MM and Meira Jr. W
The construction of a realistic theoretical model of proteins is determinant for improving the computational simulations of their structural and functional aspects. Modeling proteins as a network of non-covalent connections between the atoms of amino acid residues has shown valuable insights into these macromolecules. The ener.. Read More»
- Genet. Mol. Res. 6(4):