Demographic characterization of Brazilian patients enrolled in the Fabry Registry
Authors: A.M. Martins S.O. Kyosen J. Garrote F.M.V. Marques J.G. Guilhem E. Macedo J. Sobral Neto S. Ura
Fabry disease (FD) is an X-linked inborn error of metabolism caused by alpha-galactosidase A deficiency. The Fabry Registry is an ongoing observational database that compiles clinical data on patients with FD. We analyzed the Fabry Registry data of patients enrolled in Brazil to characterize the demographic and baseline clinical characteristics of this pa.. Read More»
- Genet. Mol. Res. 12(1):
- 2013.January.24.5
- DOI:
- 10.4238/2013.January.24.5
Comparison of random regression models to estimate genetic parameters for milk production in Guzerat (Bos indicus) cows
Authors: D.J.A. Santos M.G.C.D. Peixoto R.R. Aspilcueta Borquis R.S. Verneque J.C.C. Panetto H. Tonhati
Random regression models have been widely used to estimate genetic parameters that influence milk production in Bos taurus breeds, and more recently in B. indicus breeds. With the aim of finding appropriate random regression model to analyze milk yield, different parametric functions were compared, applied to 20,524 test-day milk yield records of 2816 fir.. Read More»
- Genet. Mol. Res. 12(1):
- 2013.January.24.6
- DOI:
- 10.4238/2013.January.24.6
Cross-species amplification of selected zebrafish, central stoneroller, and finescale dace microsatellites in lake minnow populations
Authors: D. Kaczmarczyk
Fifteen sets of PCR primers designed for the amplification of microsatellite loci from Danio rerio and Phoxinus neogaeus Campostoma DNA that have been proven applicable for molecular studies of several species of cyprinids were tested for amplification of microsatellites from lake minnow DNA. The samples were taken from 298 fish inhabiting 6 distinct popu.. Read More»
- Genet. Mol. Res. 12(1):
- 2013.January.24.7
- DOI:
- 10.4238/2013.January.24.7
Lack of association between TYK2 and STAT3 genes and Crohn�s disease in the Malaysian population
Authors: L.H. Lian T.P. Lau V.L. Lee W.S. Lee I. Hilmi K.L. Goh K.H. Chua
This study aimed to investigate the potential association of TYK2 and STAT3 genes with the susceptibility to Crohn’s disease (CD) among Malaysians. DNA samples were obtained from 80 CD patients and 100 healthy controls. Polymerase chain reaction-restriction fragment length polymorphism methods were employed for genotyping, followed by statistical an.. Read More»
- Genet. Mol. Res. 12(1):
- 2013.January.24.9
- DOI:
- 10.4238/2013.January.24.9
An efficient approach to identify Ginkgo biloba cultivars by using random amplified polymorphic DNA markers with a manual cultivar identification diagram strategy
Authors: G.P. Li C.Q. Zhang F.L. Cao
Cultivar identification is a key step to avoid the formation of homonyms and synonyms of Ginkgo biloba. In this study, a new approach based on combinational utilization of polymorphic bands produced from 6 different random amplified polymorphic DNA (RAPD) primers was developed for identifying 42 Ginkgo cultivars, and a manual cultivar identification diagr.. Read More»
- Genet. Mol. Res. 12(1):
- 2013.January.24.10
- DOI:
- 10.4238/2013.January.24.10
Multi-trait BLUP model indicates sorghum hybrids with genetic potential for agronomic and nutritional traits
Authors: J.E. Almeida Filho, F.D. Tardin, J.F.R. Guimar�£es, M.D.V. Resende, F.F. Silva, M.L. Simeone, C.B. Menezes and V.A.V. Queiroz
The breeding of sorghum, Sorghum bicolor (L.) Moench, aimed at improving its nutritional quality, is of great interest, since it can be used as a highly nutritive alternative food source and can possibly be cultivated in regions with low rainfall. The objective of the present study was to evaluate the potential and genetic diversity of grain-sorghum hybri.. Read More»
- Genet. Mol. Res. 15(1):
- gmr.15017071
- DOI:
- 10.4238/gmr.15017071
Screening of polymorphisms located in the FGF20 and TMEM175 genes in North Chinese Parkinson�s disease patients
Authors: C.C. Jing, X.G. Luo, H.G. Cui, F.R. Li, P. Li, E.Z. Jiang, Y. Ren and H. Pang
Genome-wide association studies have reported numerous susceptibility loci for Parkinson’s disease (PD). However, there have been few replication studies examining these loci in northern Chinese populations. To evaluate the relationships among 3 polymorphic markers located in the fibroblast growth factor 20 and transmembrane protein 175 genes and th.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.October.28.30
- DOI:
- 10.4238/2015.October.28.30
SNP detection using RNA-sequences of candidate genes associated with puberty in cattle
Authors: S.J. Coleman, S.E. Speidel, R.M. Enns, A. Islas-Trejo, J.F. Medrano, S.S. Moore, M.R.S. Fortes, L.T. Nguyen, B. Venus, I.S.D.P. Diaz,F.R.P. Souza, L.F.S. Fonseca, F. Baldi, L.G. Albuquerque, M.G. Thomas, H.N. Oliveira
Fertility traits, such as heifer pregnancy, are economically important in cattle production systems, and are therefore, used in genetic selection programs. The aim of this study was to identify single nucleotide polymorphisms (SNPs) using RNA-sequencing (RNA-Seq) data from ovary, uterus, endometrium, pituitary gland, hypothala.. Read More»
- Genet. Mol. Res. 16(1):
- gmr16019522
- DOI:
- 10.4238/gmr16019522
Characterization of Chinese eggplant isolates of the fungal pathogen Verticillium dahliae from different geographic origins
Authors: Z. Xu Z. Ali X. Hou H. Li J.X. Yi P.A. Abbasi
Verticillium dahliae is a fungal pathogen that causes wilt disease in a wide range of host plants. Characterization of virulence, morphological, and molecular variations among V. dahliae isolates from different geographic origins is essential for any breeding program aimed at producing plant cultivars resistant to this disease. We characterized virulence var.. Read More»
- Genet. Mol. Res. 12(1):
- 2013.January.24.11
- DOI:
- 10.4238/2013.January.24.11
Association between angiotensin-converting enzyme insertion/deletion polymorphisms and the risk of heart disease: an updated meta-analysis
Authors: F.J. You and D.M. Shen
Insertion/deletion (I/D) polymorphisms of the gene encoding angiotensin converting enzyme (ACE) are a controversial risk factor for heart diseases (HDs). ACE I/D polymorphism has been reported to be associated with various cardiovascular diseases. However, some studies have presented conflicting results. In this study, we aim to explore the association be.. Read More»
- Genet. Mol. Res. 15(1):
- gmr.15017194
- DOI:
- 10.4238/gmr.15017194