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Animal Genetics   Research Article
Cleaning cassava genotypes infected with cassava frogskin disease via in vitro shoot tip culture

Authors: M.J.S. Carvalho, E.J. Oliveira, A.S. Souza, J.S. Pereira, M.S.A.S. Diamantino and S.A.S. Oliveira

This study aimed to develop a methodology for eliminating cassava frogskin disease (CFSD) from in vitro shoot tip culture by associating thermotherapy and tetracycline. Cuttings from different accessions (BGM0232, BGM0315, BGM0464, BGM584, BGM0841, and BGM1342), infected with CFSD according to visual inspection of the disease .. Read More»

Genet. Mol. Res. 16(2): gmr16029556

DOI: 10.4238/gmr16029556

Human Genetics   Research Article
Effect of Shenqin biochemical extract on hypoxia-inducible factor-1�± expression in ultraviolet B-irradiated HaCaT cells

Authors: X. Chen, J. Bai, Y. Li, X.-G. Li1, G.-F. Lv and H.-Ch. Zhang

Hypoxia-inducible factor-1α (HIF-1α) is considered the main transcriptional regulator of the hypoxia-specific cellular and developmental response. This study was performed to investigate the effect of Shenqin biochemical extract (SQBE) on HIF-1α expression in ultraviolet B (UVB)-irradiated HaCaT cells and the.. Read More»

Genet. Mol. Res. 16(2): gmr16029430

DOI: 10.4238/gmr16029430

Plant Genetics   Research Article
Molecular diversity of Pakistani mango (Mangifera indica L.) varieties based on microsatellite markers

Authors: T. Nazish, G. Shabbir, A. Ali, S. Sami-ul-Allah, M. Naeem, M. Javed,S. Batool, H. Arshad, S.B. Hussain, K. Aslam, R. Seher, M. Tahir and M. Baber

Understanding the genetic diversity of different Pakistani mango varieties is important for germplasm management and varietal characterization. Microsatellites are efficient and highly polymorphic markers for comparative genome mapping, and were used in the present study to determine the genetic relatedness and variability amo.. Read More»

Genet. Mol. Res. 16(2): gmr16029560

DOI: 10.4238/gmr16029560

Human Genetics   Research Article
Intermediate alleles of Huntington�s disease HTT gene in different populations worldwide: a systematic review

Authors: T.A. Apolin�¡rio, C.L.A. Paiva and L.A. Agostinho

Huntington’s disease (HD) is an autosomal dominant progressive neurodegenerative disorder caused by a dynamic mutation due to the expansion of CAG repeats in the HTT gene (4p16.3). The considered normal alleles have less than 27 CAG repeats. Intermediate alleles (IAs) show 27 to 35 CAG repeats and expanded alleles have m.. Read More»

Genet. Mol. Res. 16(2): gmr16029648

DOI: 10.4238/gmr16029648

Human Genetics   Research Article
Polymorphism E23K (rs5219) in the KCNJ11 gene in Euro-Brazilian subjects with type 1 and 2 diabetes

Authors: S.W. Souza, L.P. Alcazar, P.A. Arakaki, I.C.R. Santos-Weiss, D. Alberton, G. Picheth and F.G.M. Rego

Insulin secretion is regulated by ATP-sensitive potassium channels (KATP). The potassium inwardly-rectifying channel, subfamily J, member 11 (KCNJ11) gene, located on chromosome 11p15.1, encodes the subunit Kir6.2 that forms the pore region of KATP channels in pancreatic β-cells. Among the single nucleotide polymorphisms .. Read More»

Genet. Mol. Res. 16(2): gmr16029543

DOI: 10.4238/gmr16029543

Plant Genetics   Research Article
New set of microsatellites for Chinese tallow tree, Triadica sebifera

Authors: Y.F. Zhuang, Z.F. Wang and L.F. Wu

Chinese tallow (Triadica sebifera) is an important crop and ornamental tree. After it was introduced into the USA, it gradually became a noxious invasive tree in south-eastern America since the middle of the 1900s. Because only six microsatellites were reported previously in T. sebifera, to better understand the genetic divers.. Read More»

Genet. Mol. Res. 16(2): gmr16029624

DOI: 10.4238/gmr16029624

Animal Genetics   Research Article
Brazilian strain of bovine respiratory coronavirus is derived from dual enteric and respiratory tropism

Authors: E.A. Beuttemmuller, A.F. Alfieri, S.A. Headley and A.A. Alfieri

Bovine coronavirus (BCoV) is a pathogen related to enteric and respiratory diseases in cattle worldwide. Enteric (BECoV) strains of BCoV are predominant in South America, and genetic investigations have been conducted to identify its relationship with isolates of respiratory origin (BRCoV). In this study, we used a BRCoV strai.. Read More»

Genet. Mol. Res. 16(2): gmr16029580

DOI: 10.4238/gmr16029580

Plant Genetics   Research Article
New sources of resistance to leafminers (Liriomyza sativae) in melon (Cucumis melo L.) germplasm

Authors: E.F. Celin, F.I.C. Oliveira, N.S. Dias-Pini, G.H.S. Nunes and F.A.S. Arag�£o

Leafminers (Liriomyza sativae) are the main melon (Cucumis melo L.) pests in Northeast Brazil, which is the main region for the production and export of the fruit in Brazil. Of the integrated management strategies available, genetic resistance is the best method of preventing damage by these insects. The aim of this study was .. Read More»

Genet. Mol. Res. 16(2): gmr16029561

DOI: 10.4238/gmr16029561