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Medical Genetics   Research Article
Expected coalescence times and segregating sites in a model of glacial cycles

Authors: F.F. Jesus, J.F. Wilkins, V.N. Solferini and J. Wakeley

The climatic fluctuations of the Quaternary have influenced the distribution of numerous plant and animal species. Several species suffer population reduction and fragmentation, becoming restricted to refugia during glacial periods and expanding again during interglacials. The reduction in population size may reduce the effect.. Read More»

Genet. Mol. Res. 5(3):

Animal Genetics   Research Article
Genetic trend for milk yield in Guzerat herds participating in progeny testing and MOET nucleus schemes

Authors: M.G.C.D. Peixoto, R.S. Verneque, R.L. Teodoro, V.M. Penna and M.L.Martinez

Genetic trends for 305-day milk yield (P305) in Brazilian Guzerat herds under selection were compared. Data from 4898 lactations of 3179 purebred and crossbred cows from various regions of Brazil were used. Milk yield was adjusted for mature age and the contemporary groups were defined as herd and calving year. Genetic paramet.. Read More»

Genet. Mol. Res. 5(3):

Human Genetics   Research Article
Screening for fragile X syndrome among Brazilian mentally retarded male patients using PCR from buccal cell DNA

Authors: D.M. Christofolini, M.V.N. Lipay, M.A.P. Ramos, D. Brunoni and M.I. Melaragno

Fragile X syndrome is one of the most frequent causes of mental retardation. Since the phenotype in this syndrome is quite variable, clinical diagnosis is not easy and molecular laboratory diagnosis is necessary. Usually DNA from blood cells is used in molecular tests to detect the fragile X mutation which is characterized by .. Read More»

Genet. Mol. Res. 5(3):

Animal Genetics   Research Article
Evaluation of DNA polymorphisms involving growth hormone relative to growth and carcass characteristics in Brahman steers

Authors: V.R. Beauchemin, M.G. Thomas, D.E. Franke2 and G.A. Silver

Associations of DNA polymorphisms in growth hormone (GH) relative to growth and carcass characteristics in growing Brahman steers (N = 324 from 68 sires) were evaluated. Polymorphisms were an Msp-I RFLP and a leucine/valine SNP in the GH gene as well as a Hinf-I RFLP and a histidine/arginine SNP in transcriptional regulators o.. Read More»

Genet. Mol. Res. 5(3):

Animal Genetics   Research Article
Determination of ancestral proportions in synthetic bovine breeds using commonly employed microsatellite markers

Authors: H.M.S. Bicalho, C.G. Pimenta, I.K.P. Mendes, H.B. Pena, E.M. Queiroz and S.D.J. Pena

The International Society of Animal Genetics (ISAG) has chosen nine microsatellites (international marker set) as a standard that should be included in all cattle parentage studies. They are BM1824, BM2113, INRA023, SPS115, TGLA122, TGLA126, TGLA227, ETH10, and ETH225. We decided to ascertain whether this microsatellite set co.. Read More»

Genet. Mol. Res. 5(3):

Animal Genetics   Research Article
First report of major histocompatibility complex class II loci from the Amazon pink river dolphin (genus Inia)

Authors: M. Mart�­nez-Ag�¼ero, S. Flores-Ram�­rez and M. Ruiz-Garc�­a

We report the first major histocompatibility complex (MHC) DQB1 sequences for the two species of pink river dolphins (Inia geoffrensis and Inia boliviensis) inhabiting the Amazon and Orinoco River basins. These sequences were found to be polymorphic within the Inia genus and showed shared homology with cetacean DQB- 1 sequence.. Read More»

Genet. Mol. Res. 5(3):

Animal Genetics   Research Article
Association of BoLA-DRB3.2 alleles with tick (Boophilus microplus) resistance in cattle

Authors: M.L. Martinez, M.A. Machado, C.S. Nascimento, M.V.G.B. Silva, R.L. Teodoro, J. Furlong, M.C.A. Prata, A.L. Campos, M.F.M. Guimar�£es, A.L.S. Azevedo, M.F.A. Pires and R.S. Verneque

Losses caused by bovine tick burdens in tropical countries have a tremendous economic impact on production systems. Besides reducing production, this parasite can cause death in the most susceptible animals. The use of commercial acaricides has been the major method of control, but their misuse has led to tick resistance to ma.. Read More»

Genet. Mol. Res. 5(3):

Animal Genetics   Research Article
Evaluation of the humoral immune response in BALB/c mice immunized with a naked DNA vaccine anti-methicillin-resistant Staphylococcus aureus

Authors: D.M. Roth, J.P.M. Senna and D.C. Machado

Methicillin-resistant Staphylococcus aureus (MRSA) is the major pathogen involved in nosocomial infections, leading to high rates of morbidity and mortality in hospitals worldwide. The methicillin resistance occurs due to the presence of an additional penicillin-binding protein, PBP2a, which has low affinity for β-lactam .. Read More»

Genet. Mol. Res. 5(3):