D. Simon
Lack of association between human leukocyte antigen polymorphisms rs9277535 and rs7453920 and chronic hepatitis B in a Brazilian population
Hepatitis B virus (HBV) infection is a serious public health problem worldwide. The progression of the disease depends on several host and viral factors and may result in fulminant hepatitis (very rare), acute hepatitis with spontaneous clearance, and chronic hepatitis B infection. Previous studies demonstrated that variations in the human leukocyte antigen (HLA) cl.. Read More»
Genet. Mol. Res. 16(2): gmr16029565
DOI: 10.4238/gmr16029565
Matrix metalloproteinase gene polymorphisms and susceptibility to systemic sclerosis
The major pathological hallmark of the systemic sclerosis (SSc) is skin and internal organ fibrosis, which results from normal tissue architecture alterations and extracellular matrix (ECM) protein deposition. ECM components are degraded by matrix metalloproteinases (MMP). Promoter region polymorphisms in MMP genes may influence gene expression, resulting in an imba.. Read More»
Genet. Mol. Res. 15(4): gmr15049077
DOI: 10.4238/gmr15049077
Prevalence and genotypic diversity of cervical human papillomavirus infection among women from an urban center in Brazil
Human papillomavirus (HPV) infection is a common viral sexually transmitted infection and the main cause of cervical cancer in women worldwide. Epidemiological data on the prevalence of HPV in a given population is essential for the establishment of effective prevention strategies. The aim of this study was to determine HPV prevalence in women who attended a public health service within an urba.. Read More»
Genet. Mol. Res. 12(4): 2013.February.19.3
DOI: 10.4238/2013.February.19.3
Influence of CYP2C19 on Helicobacter pylori eradication in Brazilian patients with functional dyspepsia
The aim of this study was to examine the effect of polymorphisms in the cytochrome P450 (CYP) 2C19 gene (CYP2C19) on the Helicobacter pylori eradication rate in Brazilian patients with functional dyspepsia. Adults diagnosed with functional dyspepsia based on the ROME III criteria and infected with H. pylori were recruited to this study. The patients were subjected to gastrointestinal endoscopy .. Read More»
Genet. Mol. Res. 15(3): gmr.15038734
DOI: 10.4238/gmr.15038734
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