Animal Genetics
Genes up- and down-regulated by dermcidin in breast cancer: a microarray analysis
Authors: D.F. Moreira, B.E. Strauss, E. Vannier and J.E. Beliz�¡rio
3-fold change and p 0.005). The gene expression of 208 was reduced and of 27 was increased in the three DCD-RNAi clones compared to pLKO control clone. The expression of 77 genes (37%) encoding for enzymes involved in amino acid metabolism, glucose metabolism and oxidoreductase activity and several genes required for cell surv.. Read More»
- Genet. Mol. Res. 7(3):
- vol7-3x-meeting009
- DOI:
- 10.4238/vol7-3x-meeting009
Isolation and characterization of microsatellite loci in the fish Coilia mystus (Clupeiformes: Engraulidae) using PCR-based isolation of microsatellite arrays
Authors: J.-Q. Yang, X.-D. Zhou, D. Liu, Z.-Z. Liu and W.-Q. Tang
Coilia mystus is the most important harvested fish species in China; it inhabits quite different water environments during the different life history stages. Populations of C. mystus have dropped sharply due to overharvesting and water pollution. We developed eight microsatellite loci in C. mystus for conservation genetics stu.. Read More»
- Genet. Mol. Res. 10(3):
- vol10-3gmr1420
- DOI:
- 10.4238/vol10-3gmr1420
A simple and efficient method for predicting protein-protein interaction sites
Authors: R.H. Higa and C.L. Tozzi
Computational methods for predicting protein-protein interaction sites based on structural data are characterized by an accuracy between 70 and 80%. Some experimental studies indicate that only a fraction of the residues, forming clusters in the center of the interaction site, are energetically important for binding. In additi.. Read More»
- Genet. Mol. Res. 7(3):
- vol7-3x-meeting07
- DOI:
- 10.4238/vol7-3x-meeting07
The full Bayesian significance test for mixture models: results in gene expression clustering
Authors: M.S. Lauretto, C.A.B. Pereira and J.M. Stern
Gene clustering is a useful exploratory technique to group together genes with similar expression levels under distinct cell cycle phases or distinct conditions. It helps the biologist to identify potentially meaningful relationships between genes. In this study, we propose a clustering method based on multivariate normal mixt.. Read More»
- Genet. Mol. Res. 7(3):
- vol7-3x-meeting06
- DOI:
- 10.4238/vol7-3x-meeting06
Statistical analyses of conserved features of genomic islands in bacteria
Authors: F.-B. Guo, Z.-K. Xia, W. Wei and H.-L. Zhao
We performed statistical analyses of five conserved features of genomic islands of bacteria. Analyses were made based on 104 known genomic islands, which were identified by comparative methods. Four of these features include sequence size, abnormal G+C content, flanking tRNA gene, and embedded mobility gene, which are frequent.. Read More»
- Genet. Mol. Res. 13(1):
- http://dx.doi.org/2014.March.17.6
- DOI:
- http://dx.doi.org/10.4238/2014.March.17.6
ChromaPipe: a pipeline for analysis, quality control and management for a DNA sequencing facility
Authors: T.D. Otto, E.A. Vasconcellos, L.H.F. Gomes, A.S. Moreira,W.M. Degrave, L. Mendon�§a-Lima and M. Alves-Ferreira
Optimizing and monitoring the data flow in high-throughput sequencing facilities is important for data input and output, for tracking the status of results for the users of the facility, and to guarantee a good, high-quality service. In a multi-user system environment with different throughputs, each user wants to access his/h.. Read More»
- Genet. Mol. Res. 7(3):
- vol7-3x-meeting04
- DOI:
- 10.4238/vol7-3x-meeting04
Polymorphisms in the bone morphogenetic protein 15 gene and their effect on sperm quality traits in Chinese Holstein bulls
Authors: L.P. Sun, Y.P. Song, Q.Z. Du, L.W. Song, Y.Z. Tian, S.L. Zhang,G.H. Hua and L.G. Yang
Bone morphogenetic protein 15 (BMP-15) expression has been detected in the testis, but its roles in this organ has not been well elucidated. We evaluated polymorphisms of the BMP-15 gene by PCR-SSCP and PCR-RFLP in 212 Chinese Holstein bulls, and investigated possible associations with sperm quality traits, including semen vol.. Read More»
- Genet. Mol. Res. 13(1):
- http://dx.doi.org/2014.March.17.8
- DOI:
- http://dx.doi.org/10.4238/2014.March.17.8
Gene expression profiling: identification of genes with altered expression in Ayu17-449 knockout mice
Authors: Y. Li, T.T. Huang, H. Tang, K.I. Yamamura and X.Y. Pu
Ayu17-449, a novel gene in mice, has been identified as a tumor-suppressor gene in myeloid malignancy; its product catalyzes the conversion of 5-methylcytosine of DNA to 5-hydroxymethylcytosine. However, in vivo, its functional target genes and biological function have remained unclear. Based on the assumption that alterations.. Read More»
- Genet. Mol. Res. 10(3):
- vol10-3gmr1158
- DOI:
- 10.4238/vol10-3gmr1158
Comparison of complete mitochondrial DNA control regions among five Asian freshwater turtle species and their phylogenetic relationships
Authors: Y. Jiang, L.W. Nie, Z.F. Huang, W.X. Jing, L. Wang, L. Liu and X.T. Dai
The complete mitochondrial DNA (mtDNA) control regions (CR), cytochrome b (Cyt b), NADH dehydrogenase subunit 4 (ND4) and cytochrome coxidase subunit I (CO I) genes of four Asian freshwater turtles, Mauremys japonica, Ocadia sinensis, M. mutica, and Annamemys annamensis, were sequenced using universal PCR and long-PCR techniqu.. Read More»
- Genet. Mol. Res. 10(3):
White mold resistance-associated quantitative trait loci in the Jalo x Small White common bean population
Authors: D.A. Souza, M. Balestre, A.K.A. Pamplona, M.E. Leite, J.A. Dias and J.B. Santos
We aimed to identify simple sequence repeat (SSR) markers linked to quantitative trait loci (QTLs) associated with white mold resistance in a segregating population derived from a cross between common bean cultivars Jalo and Small White, in the Southern State of Minas Gerais. Parents were crossed to obtain the F2 generation of 190 plants. From these, F2:3.. Read More»
- Genet. Mol. Res. 15(3):
- gmr.15038724
- DOI:
- 10.4238/gmr.15038724