Animal Genetics
Simulation of normal, carrier and affected controls for large-scale genotyping of cattle for factor XI deficiency P.
Authors: P.N. Mukhopadhyaya, M. Jha, P. Muraleedharan, R.R. Gupta, R.N. Rathod, H.H. Mehta and V.K. Khoda
An insertion mutation within exon 12 of the factor XI gene has been described in Holstein cattle. This has opened the prospect for large-scale screening of cattle using the polymerase chain reaction (PCR) technique for the rapid identification of heterozygous animals. To facilitate such a screening process, the mutant and norm.. Read More»
- Genet. Mol. Res. 5(2):
Morphological evolution and heritability estimates for some biometric traits in the Murgese horse breed
Authors: C. Dario, D. Carnicella, M. Dario and G. Bufano
A data set concerning 1,816 subjects entered in the Italian Horse Registry from 1925 to 2002 was analyzed to investigate the morphological evolution of the Murgese horse and to obtain useful elements to enhance breeding practices. Three basic body measurements (height at withers, chest girth, and cannon bone circumference) wer.. Read More»
- Genet. Mol. Res. 5(2):
Ion-exchange chromatography used to isolate a spermadhesin-related protein from domestic goat (Capra hircus) seminal plasma
Authors: D?¡rcio ?talo Alves Teixeira, Luciana Magalh?£es Melo, Carlos Alberto de Almeida Gadelha, Rodrigo Maranguape Silva da Cunha, Carlos Bloch Jr., Gandhi R?¡dis-Baptista, Benildo Sousa Cavada and Vicente Jos?© de Figueir?ªdo Freitas
Mammalian seminal plasma contains among others, proteins called spermadhesins, which are the major proteins of boar and stallion seminal plasma. These proteins appear to be involved in capacitation and sperm-egg interaction. Previously, we reported the presence of a protein related to spermadhesins in goat seminal plasma. In t.. Read More»
- Genet. Mol. Res. 5(1):
Well-balanced commensal microbiota contributes to anti-cancer response in a lung cancer mouse model
Authors: Q.-F. Gui, H.-F. Lu, C.-X. Zhang, Z.-R. Xu and Y.-M. Yang
The intestinal microflora affects inflammation and immunity, not only locally at the mucosal level but also systemically, raising the question of whether the microflora affects inflammatory processes that contribute to cancer and its therapy. Prebiotics have also been found to play an antitumor role that is not limited to the gut. We investigated the anti.. Read More»
- Genet. Mol. Res. 14(2):
- 2015.May.25.16
- DOI:
- 10.4238/2015.May.25.16
Analysis of Fcgrt gene polymorphism in indigenous Chinese sheep and its association with colostrum IgG concentration
Authors: Z.H. Tian, F. Shi, F.G. Zhong, D.P. Bai and X.Y. Zhang
The neonatal Fc receptor (FcRn) plays an important role in regulating IgG homeostasis in the body and passive protection to the offspring. Changes in FcRn expression levels caused by genetic polymorphisms of Fcgrt, which encodes FcRn, may lead to inter-individual differences in colostrum IgG levels in sheep. In this study, we sequenced the FcRn partial he.. Read More»
- Genet. Mol. Res. 14(1):
- http://dx.doi.org/2015.March.30.4
- DOI:
- http://dx.doi.org/10.4238/2015.March.30.4
Performance of genomic data sets on the estimation of the divergence time of New World and Old World anthropoids
Authors: C.G. Schrago and C.M. Voloch
The origin of New World anthropoids has received renewed attention since the advent of molecular dating methods that relax the assumption of a strict molecular clock. However, the studies conducted to date have estimated the time of the separation of New World and Old World anthropoids at values as different as 70 and 22 Ma. W.. Read More»
- Genet. Mol. Res. 13(1):
- http://dx.doi.org/2014.March.6.1
- DOI:
- http://dx.doi.org/10.4238/2014.March.6.1
A comparative analysis of highly conserved sex-determining genes between Apis mellifera and Drosophila melanogaster
Authors: Alexandre S. Cristino, Adriana Mendes do Nascimento, Luciano da Fontoura Costa and Zil?¡ Luz Paulino Sim?µes
A comparison of the most conserved sex-determining genes between the fruit fly, Drosophila melanogaster, and the honey bee, Apis mellifera, was performed with bioinformatics tools developed for computational molecular biology. An initial set of protein sequences already described in the fruit fly as participants of the sex-det.. Read More»
- Genet. Mol. Res. 5(1):
Identification and characterization of microRNAs expressed in chicken skeletal muscle
Authors: A.P.D. Andreote, M.F. Rosario, M.C. Ledur, E.C. Jorge,T.S. Sonstegard, L. Matukumalli and L.L. Coutinho
MicroRNAs (miRNAs, miRs) encompass a class of small non-coding RNAs that often negatively regulate gene expression. miRNAs play an essential role in skeletal muscle, determining the proper development and maintenance of this tissue. In comparison to other organs and tissues, the full set of muscle miRNAs and its expression pat.. Read More»
- Genet. Mol. Res. 13(1):
- http://dx.doi.org/2014.March.6.5
- DOI:
- http://dx.doi.org/10.4238/2014.March.6.5
Use of fluorescent-based amplified fragment length polymorphism to resolve phylogenetic relationships of Colchicum species from Turkey
Authors: ??. Karaka?? Metin, M. T?¼rkta??, F. Ertu??rul and E. Kaya
The study of phylogenetic relationships between 14 Colchicum taxa spread throughout Turkey was performed using a fluorescent-based amplified fragment length polymorphism (AFLP) technique. Five primer pair combinations were used in AFLP reactions. The data set was analyzed statistically using the NTSYS 2.1 software, and the nei.. Read More»
- Genet. Mol. Res. 13(1):
- http://dx.doi.org/2014.March.6.6
- DOI:
- http://dx.doi.org/10.4238/2014.March.6.6
Target fishing of glycopentalone using integrated inverse docking and reverse pharmacophore mapping approach
Authors: A.B. Gurung, M.A. Ali, A. Bhattacharjee, K.M. Al-Anazi, M.A. Farah, F.M. Al-Hemaid, F.M. Abou-Tarboush, J. Lee, S.Y. Kim and F.S.M. Al-Anazi
Glycopentalone isolated from Glycosmis pentaphylla (family Rutaceae) has cytotoxic and apoptosis inducing effects in various human cancer cell lines; however, its mode of action is notknown. Therefore, target fishing of glycopentalone using a combined approach of inverse docking and reverse pharmacophore mapping approach was used to identify potential tar.. Read More»
- Genet. Mol. Res. 15(3):
- gmr.15038544
- DOI:
- 10.4238/gmr.15038544