Animal Genetics
Induced immune tolerance of autoantigen loaded immature dendritic cells in homogenic lupus mice
Authors: J. Xie, Y.K. Lin, K. Wang, B. Che, J.Q. Li, X. Xu, F. Han andD.H. Liang
This study investigated the induced immune tolerance of autoantigen dendritic cells (imDCs) in homogenic lupus mice to support the use of dendritic cell treatment against autoimmune diseases, such as systemic lupus erythematosus. A lupus mouse was used to model based on in vitro cell culture. An immunohistochemistry assay was .. Read More»
- Genet. Mol. Res. 13(1):
- http://dx.doi.org/2014.February.27.10
- DOI:
- http://dx.doi.org/10.4238/2014.February.27.10
Resistance to lipopolysaccharide-induced endotoxic shock in heterozygous Zfp191 gene-knockout mice
Authors: R.L. Sun, H.Y. Wang, X.Y. Yang, Z.J. Sheng, L.M. Li, L. Wang, Z.G. Wang and J. Fei
Zinc finger protein 191, ZNF24 and Zfp191 in both humans and mice belong to the SCAN domain subfamily of Krüppel-like zinc finger transcription factors. Previous studies have suggested that Zfp191 is a pleiotropic factor involved in embryonic development, hematopoiesis and tumorigenesis. However, little is known about its.. Read More»
- Genet. Mol. Res. 10(4):
- 2011.December.8.6
- DOI:
- 10.4238/2011.December.8.6
Development and characterization of 32 microsatellite loci in the giant grouper Epinephelus lanceolatus (Serranidae)
Authors: S. Yang, L. Wang, Y. Zhang, X.C. Liu, H.R. Lin and Z.N. Meng
An economically important marine fish species, the giant grouper Epinephelus lanceolatus (Serranidae) is widely cultured in Taiwan and costal areas of China. We isolated and characterized 32 polymorphic microsatellite loci from a CA-enriched genomic library of giant grouper. The number of alleles per locus ranged from 3 to 7, .. Read More»
- Genet. Mol. Res. 10(4):
- 2011.December.12.3
- DOI:
- 10.4238/2011.December.12.3
Function Clustering Self-Organization Maps (FCSOMs) for mining differentially expressed genes in Drosophila and its correlation with the growth medium
Authors: L.L. Liu, M.J. Liu and M. Ma
The central task of this study was to mine the gene-to-medium relationship. Adequate knowledge of this relationship could potentially improve the accuracy of differentially expressed gene mining. One of the approaches to differentially expressed gene mining uses conventional clustering algorithms to identify the gene-to-medium relationship. Compared to co.. Read More»
- Genet. Mol. Res. 14(3):
- DOI http://dx.doi.org/2015.September.28.18
- DOI:
- DOI http://dx.doi.org/10.4238/2015.September.28.18
Back fat thickness and meat tenderness are associated with a 526 T�A mutation in the exon 1 promoter region of the MyF-5 gene in Chinese Bos taurus
Authors: J.A. Ujan, L.S. Zan, S.A. Ujan, C. Adoligbe and H.B. Wang
Qualitative trait loci (QTL) for growth and meat quality traits in cattle (Bos taurus) have been previously mapped to three chromosome regions, 0 to 30, 55 to 70, and 70 to 80 cM on chromosome 5. We evaluated the allele frequencies and gene-specific single nucleotide polymorphisms (SNPs) of bovine myogenic factor 5 (MyF-5) in .. Read More»
- Genet. Mol. Res. 10(4):
- 2011.December.12.6
- DOI:
- 10.4238/2011.December.12.6
Development of microsatellite markers for Hoplias malabaricus (Erythrinidae)
Authors: S.G.C.A. Gondim, L.V. Resende, R.P.V. Brondani, R.G. Collevatti, N.J. Silva-J�ºnior, R.R. Pereira and M.P.C. Telles
We identified 14 microsatellite loci for the wolf fish, Hoplias malabaricus (Erythrinidae), from a genomic shotgun library. Twenty-five primers were designed, and 48 individuals of H. malabaricus from four localities of northwest Goiás, in central Brazil, were genotyped to characterize the polymorphism at each locus. Fo.. Read More»
- Genet. Mol. Res. 9(3):
- vol9-3gmr877
- DOI:
- 10.4238/vol9-3gmr877
Ulinastatin promotes T lymphocyte apoptosis in rats with severe acute pancreatitis via mitochondrial pathways
Authors: C.L. Wang, N. Li, T. Ma, P. Zhang and S.Y. You
We explored the influence of ulinastatin on apoptosis of T lymphocytes in rats with severe acute pancreatitis (SAP) and the effect of ulinastatin on mitochondrial apoptosis pathways in spleen lymphocytes. Thirty-six Wistar rats were randomly divided into three groups (N = 12): a sham operated group, a SAP group, and an ulinastatin-treated SAP group. The S.. Read More»
- Genet. Mol. Res. 14(2):
- 2015.May.25.2
- DOI:
- 10.4238/2015.May.25.2
Development of polymorphic expressed sequence tag-single sequence repeat markers in the common Chinese cuttlefish, Sepiella maindroni
Authors: R.H. Li, S.K. Lu, C.L. Zhang, W.W. Song, C.K. Mu and C.L. Wang
The common Chinese cuttlefish (Sepiella maindroni) is one of the popular edible cephalopod consumed across Asia. To facilitate the population genetic investigation of this species, we developed fourteen polymorphic microsatellite makers from expressed sequence tags of S. maindroni. The number of alleles at ea.. Read More»
- Genet. Mol. Res. 13(3):
- 2014.July.25.3
- DOI:
- 10.4238/2014.July.25.3
Detection of novel SNPs and mapping of the fatness QTL on pig chromosome 7q1.1-1.4 region
Authors: W.H. Huang, Z.X. Ma, Z.Y. Xu, Y.Z. Xiong and B. Zuo
Many QTLs for fatness traits have been mapped on pig chromosome 7q1.1-1.4 in various pig resource populations. Eight novel markers, including seven SNPs and one insertion or deletion within BTNL1, COL21A1, PPARD, GLP1R, MDFI, GNMT, ABCC10, and PLA2G7 genes, as well as two previously reported SNPs in SLC39A7 and HMGA1 genes, we.. Read More»
- Genet. Mol. Res. 10(4):
- 2011.December.14.2
- DOI:
- 10.4238/2011.December.14.2
Development of eight novel microsatellite markers for Huoyan geese
Authors: Z.Z. Cao, D. Su, Y.Y. Zhao, M. Liu, M. Gao and X.H. Luan
In this study, we isolated microsatellite DNA from the Huoyan goose genome with magnetic beads. As a result, 150 positive clones were identified, and 148 microsatellites were found. Among the 148 microsatellites, 69.6% were perfect, 17.6% were imperfect, and the rest were compound type (12.8%). Twenty microsatellite primers we.. Read More»
- Genet. Mol. Res. 13(3):
- 2014.July.25.10
- DOI:
- 10.4238/2014.July.25.10