Animal Genetics
Increase in mitochondrial DNA quantity and impairment of oxidative phosphorylation in bovine fibroblast cells treated with ethidium bromide for 15 passages in culture
Authors: Marcos Roberto Chiaratti and Fl�¡vio Vieira Meirelles
Bovine fetal fibroblast cells were treated with ethidium bromide at a low concentration for 15 passages in culture to determine its effect on mitochondrial DNA copy number and on cell metabolism. Mitochondrial membrane potential and lactate production were estimated in order to characterize cell metabolism. In addition, mitoch.. Read More»
- Genet. Mol. Res. 5(1):
A novel polymorphism of the myogenin gene is associated with body measurement traits in native Chinese breeds
Authors: M. Xue, L.S. Zan, L. Gao and H.B. Wang
Using PCR-SSCP and DNA sequencing technology, we examined the association of single nucleotide polymorphisms (SNPs) in the bovine MyoG gene with body measurement traits in 779 individuals of six native Chinese cattle breeds, namely Luxi, Luxi × Simmental crossbred, Nanyang, Xia’nan, Jiaxian red, and Qinchuan. A nov.. Read More»
- Genet. Mol. Res. 10(4):
- 2011.November.4.6
- DOI:
- 10.4238/2011.November.4.6
AGPAT6 polymorphism and its association with milk traits of dairy goats
Authors: C. He, C. Wang, Z.H. Chang, B.L. Guo, R. Li, X.P. Yue, X.Y. Lan, H. Chen and C.Z. Lei
As one of the eight members in the 1-acylglycerol-3-phosphate-O-acyltransferase (AGPATs) family, AGPAT6 is a crucial enzyme for the biosynthesis of glycerolipids and triacylglycerol in eukaryotes, as well as catalyzing the conversion from lysophosphatidic acid to phosphatidic acid. AGPAT6 can be considered as a candidate gene .. Read More»
- Genet. Mol. Res. 10(4):
- 2011.November.4.8
- DOI:
- 10.4238/2011.November.4.8
Estimation of genetic parameters and variance components for growth traits in Romosinuano cattle in the Colombian humid tropics
Authors: Sarmiento RM and Garcia JP
(Co)variance components and genetic parameters were estimated for body weights of a Romosinuano herd located in Sinú Valley, Cordoba, Colombia. Restricted maximum likelihood methods were used with a univariate animal model for birth weight, weaning weight (270 days), 16-month weight (480 days), weaning daily gain, and p.. Read More»
- Genet. Mol. Res. 6(3):
Analysis of agouti signaling protein (ASIP) gene polymorphisms and association with coat color in Tibetan sheep (Ovis aries)
Authors: J.L. Han, M. Yang, Y.J. Yue, T.T. Guo, J.B. Liu, C.E. Niu and B.H. Yang
Tibetan sheep, an indigenous breed, have a wide variety of phenotypes and a colorful coat, which make this breed an interesting model for evaluating the effects of coat-color gene mutations on this phenotypic trait. The agouti signaling protein (ASIP) gene is a positional candidate gene, as was inferred based on previous study. In our research, ASIP gene .. Read More»
- Genet. Mol. Res. 14(1):
- 2015.February.6.22
- DOI:
- 10.4238/2015.February.6.22
Identification of transgenic cloned dairy goats harboring human lactoferrin and methylation status of the imprinted gene IGF2R in their lungs
Authors: Y.L. Zhang, G.M. Zhang, Y.J. Wan, R.X. Jia, P.Z. Li, L. Han, F. Wang and M.R. Huang
Dairy goat is a good model for production of transgenic proteins in milk using somatic cell nuclear transfer (SCNT). However, animals produced from SCNT are often associated with lung deficiencies. We recently produced six transgenic cloned dairy goats harboring the human lactoferrin gene, including three live transgenic clones and three deceased transgen.. Read More»
- Genet. Mol. Res. 14(3):
- http://dx.doi.org/2015.September.22.3
- DOI:
- http://dx.doi.org/10.4238/2015.September.22.3
Molecular cloning and expression analysis of MAT1 gene in black tiger shrimp (Penaeus monodon)
Authors: Y. Wang1,2*, M.J. Fu1,3*, C. Zhao1,3, W.Y. Bao3, F.L. Zhou1,3, Q.B. Yang1,3,4, S.G. Jiang1,3 and L.H. Qiu1,3
MAT1 (ménage à trois 1), an assembly factor and targeting subunit of the CDK-dependent kinase (CAK), can regulate the cell cycle, transcription, and DNA repair. This study was intended to investigate the role of MAT1 in the reproductive maturation of black tiger shrimp (Penaeus monodon). In this study, the P. monodon MAT1 (PmMAT1) gene was i.. Read More»
- Genet. Mol. Res. 15(1):
A genetic analysis of post-weaning feedlot performance and profitability in Bonsmara cattle
Authors: R.R. van der Westhuizen J. van der Westhuizen S.J. Schoeman
The aim of this study was to identify factors influencing profitability in a feedlot environment and to estimate genetic parameters for and between a feedlot profit function and productive traits measured in growth tests. The heritability estimate of 0.36 for feedlot profitability shows that this trait is genetically inherited.. Read More»
- Genet. Mol. Res. 8(1):
- vol8-1gmr535
- DOI:
- 10.4238/vol8-1gmr535
Transcriptional co-activator PGC-1�± gene is associated with chicken skeletal muscle fiber types..
Authors: J.T. Shu, W.J. Xu, M. Zhang, W.T. Song, Y.J. Shan, C. Song, W.Q. Zhu, X.Y. Zhang and H.F. Li
The peroxisome proliferators-activated receptor-γ coactivator-1α (PGC-1α) is a candidate gene for meat quality traits because of its prominent role in muscle fiber type switching and determination. We investigated the effects of the PGC-1α gene on chicken skeletal muscle fiber type switching and on othe.. Read More»
- Genet. Mol. Res. 13(1):
- 2014.February.14.19
- DOI:
- 10.4238/2014.February.14.19
Allelic variability in the third intron of the fibroin light chain gene in Bombyx mori (Lepidoptera: Bombycidae)
Authors: J.F. Barbosa J.P. Bravo D.B. Zanatta J.L.C. Silva M.A. Fernandez
Conformation-sensitive gel electrophoresis is a useful method for identifying allele polymorphism; it provides co-dominant molecular markers. Using this method, we identified genetic variability in the third intron of the fibroin light chain gene, fib-L, in six Bombyx mori strains. Only Chinese C21A strain did not demonstrate .. Read More»
- Genet. Mol. Res. 8(1):
- vol8-1gmr543
- DOI:
- 10.4238/vol8-1gmr543