Animal Genetics
Molecular cloning, polymorphisms, and expression analysis of the RERG gene in indigenous Chinese goats
Authors: M.X. Sui, H.H. Wang and Z.W. Wang
The current study aimed to investigate the coding sequence, polymorphisms, and expression of the RERG gene in indigenous Chinese goats. cDNA of RERG, obtained through reverse transcription PCR was analyzed using bioinformatic techniques. Polymorphisms in the exon regions of the RERG gene were identified and their associations .. Read More»
- Genet. Mol. Res. 14(4):
- 2015.November.24.1
- DOI:
- 10.4238/2015.November.24.1
Novel single nucleotide polymorphisms of the bovine methyltransferase 3b gene and their association with meat quality traits in beef cattle
Authors: X. Liu, X.Y. Guo, X.Z. Xu, M. Wu, X. Zhang, Q. Li, P.P. Ma, Y. Zhang, C.Y. Wang, F.J. Geng, C.H. Qin, L. Liu, W.H. Shi, Y.C. Wang and Y. Yu
DNA methylation is essential for adipose deposition in mammals. We screened SNPs of the bovine DNA methyltransferase 3b (DNMT3b) gene in Snow Dragon beef, a commercial beef cattle population in China. Nine SNPs were found in the population and three of six novel SNPs were chosen for genotyping and analyzing a possible association with 16 meat quality trai.. Read More»
- Genet. Mol. Res. 11(3):
- 2012.June.29.1
- DOI:
- 10.4238/2012.June.29.1
Targeting exogenous GDNF gene to the bovine somatic cell beta-casein locus for the production of transgenic bovine animals
Authors: X.M. Zhang, F.H. Luo, H.M. Ding, B. Li, J.J. Zhang and Y.J. Wu
Considerable attention is currently being directed toward methods for producing recombinant human proteins in the mammary glands of genetically modified transgenic livestock. However, the expression of inserted genes in transgenic animals is variable and often very low because of the randomness of the site of transgene integra.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.November.24.6
- DOI:
- 10.4238/2015.November.24.6
Physical mapping of 18S and 5S rDNA loci and histone H3 gene in grasshopper species of the subfamily Gomphocerinae (Acrididae)
Authors: L.C. Silva-Neto, A.C.S. Bernardino, V. Loreto and R.C. Moura
In this study, fluorescence in situ hybridization (FISH) analysis was used to determine and compare the numbers and chromosomal locations of two multigene families (rDNA and histone H3) in four Neotropical species of gomphocerine grasshoppers. FISH using the 18S rDNA probe identified a single site on the S9 chromosome.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.November.24.8
- DOI:
- 10.4238/2015.November.24.8
Hematological markers and biochemical profiles in terms of gender and age of captive collared peccaries (Tayassu tajacu) in eastern Amazon
Authors: E.M. Jorge, C.J.O. Silva, R.A. Ritter, M.V.B. Monteiro, N.I. Albuquerque, P.R. Kahwage, F.O.B. Monteiro, C.T.C. Costa, S.C. Rahal and E. Silva Filho
Complete blood counts and blood biochemical analyses are laboratory tests that allow the monitoring of physiological condition, nutrition, and health in free-living or captive wild animals. When interpreting these tests, it is essential to compare the results with reference ranges that are suitable for the species. Few studies.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.November.24.7
- DOI:
- 10.4238/2015.November.24.7
Polymorphisms of PRLR and FOLR1 genes and association with milk production traits in goats
Authors: J.X. Hou, F. Fang, X.P. An, Y. Yan, T. Ma , P. Han , F.X. Meng , Y.X. Song , J.G. Wang and B.Y. Cao
We investigated the polymorphisms of PRLR and FOLR1 genes in Xinong Saanen, Guanzhong, and Boer goat breeds by DNA sequencing and PCR–RFLP. Two novel SNPs were identified: KC109741: g.62130C>T in the 3êÂ?Â?-UTR of goat gene PRLR, and KC136296: g.7884A>C in exon 3 of goat gene FOLR1. In the three goat breeds, the p.. Read More»
- Genet. Mol. Res. 13(2):
- 2014.January.24.1
- DOI:
- 10.4238/2014.January.24.1
RANTES gene polymorphisms (-403G>A and -28C>G) associated with hepatitis B virus infection in a Saudi population
Authors: A. Al-Qahtani, S. Alarifi, M. Al-Okail, Z. Hussain4, A. Abdo, F. Sanai, M. Al-Anazi, N. Khalaf, H. Al-Humaidan, M. Al-Ahdal and F.N. Almajhdi
Besides the host immune response, genetic and environmental factors play crucial roles in the manifestation of hepatitis B virus (HBV) infection. “Regulated on activation normal T-cell expressed and secreted” factor (RANTES) plays a vital role in CD4+, CD8+ T-lymphocyte and dendritic cell activation and proliferati.. Read More»
- Genet. Mol. Res. 11(2):
- 2012.April.10.1
- DOI:
- 10.4238/2012.April.10.1
Comparative cytogenetics of spiny rats of the genus Proechimys (Rodentia, Echimyidae) from the Amazon region
Authors: E.S. Eler, M.N.F. da Silva, C.E.F. Silva and E. Feldberg
We made a comparative analysis of the cytogenetics of spiny rat species of the genus Proechimys collected from several sites of the Madeira River basin (Amazonas State, Brazil) and Jari River valley (Pará State, Brazil). Individuals were assigned to three groups based on diploid and fundamental numbers: 2n = 28, FN = 46.. Read More»
- Genet. Mol. Res. 11(2):
- 2012.April.3.5
- DOI:
- 10.4238/2012.April.3.5
Drynaria total flavonoids decrease cathepsin K expression in ovariectomized rats
Authors: X.L. Shi1, C.W. Li2, Q.Z. Wan2, A.Q. Li2, H. Wang1 and K. Liu
This study investigated the effects of Drynaria total flavonoids on cathepsin K serum concentrations and gene expression, biomechanics and bone mineral density (BMD) of the tibial shaft in ovariectomized rat models of osteoporosis, and mechanism in the prevention and cure of osteoporosis. Seventy-two female Sprague-Dawley rats.. Read More»
- Genet. Mol. Res. 13(2):
- http://dx.doi.org/2014.June.9.17
- DOI:
- http://dx.doi.org/10.4238/2014.June.9.17
Novel polymorphic microsatellite markers for Bellamya and their application in population genetics of three species
Authors: Q.H. Gu, Q.Q. Cheng, X.J. Li and C.J. Zhou
Bellamya is a widely distributed freshwater snail genus in China; however, its genetic diversity is completely unknown. Sixty-five novel microsatellite loci were isolated and characterized from a microsatellite-enriched library of Bellamya aeruginosa genomic DNA. Most of the 65 loci were successfully amplified. We fou.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.November.25.8
- DOI:
- 10.4238/2015.November.25.8