Animal Genetics
Roles of Fas/Fasl, Bcl-2/Bax, and Caspase-8 in rat nonalcoholic fatty liver disease pathogenesis
Authors: C.P. Li, J.H. Li, S.Y. He, P. Li and X.L. Zhong
The aim of this study was to investigate the roles of Fas/FasL, Bcl-2/Bax, and Caspase-8 mRNA expressions in nonalcoholic fatty liver disease (NAFLD). The apoptosis percentage was measured by flow cytometry, the immunohistochemical assay was performed for the determination of Fas, FasL, Bcl-2, and Bax expressions, and a real-t.. Read More»
- Genet. Mol. Res. 13(2):
- http://dx.doi.org/2014.May.23.10
- DOI:
- http://dx.doi.org/10.4238/2014.May.23.10
Genetic differences between the wild and hatchery-produced populations of Korean short barbeled grunter (Hapalogenys nitens) determined with microsatellite markers
Authors: H.S. An, H.W. Kang, H.S. Han, J.Y. Park, C.G. Hong, J. Park, J.I. Myeong and C.M. An
Short barbeled grunter, Hapalogenys nitens, is an economically important fishery resource. In Korea, this fish is in the early stage of domestication, and it has been regarded as the candidate marine fish species for prospective aquaculture diversification. This study presents a preliminary investigation of the future viability of sustainable fry producti.. Read More»
- Genet. Mol. Res. 13(4):
Expression of cationic amino acid transporters, carcass traits, and performance of growing pigs fed low-protein amino acid-supplemented versus high protein diets
Authors: A. Morales, F. Grageola, H. GarcÃ?Âa, A. Araiza, R.T. Zijlstra and M. Cervantes
Free amino acids (AA) appear to be absorbed faster than protein-bound AA (PB-AA). We conducted an experiment to assess the effect of feeding pigs with a partially free (F-AA) or totally PB-AA diet on expression of selected genes and performance of pigs. The expression of cationic AA transporters b0,+ and CAT-1 in intestinal mucosa, liver, and longissimus .. Read More»
- Genet. Mol. Res. 12(4):
- 2013.October.18.9
- DOI:
- 10.4238/2013.October.18.9
Universal primers to amplify the complete mitochondrial 12S rRNA gene in marine fish species
Authors: X.X. Jin, S.L. Zhao, R.X. Wang
A pair of new universal 12S mitochondrial rRNA gene primers was designed through multiple alignment analysis of the mitochondrial tRNAPhe and the 5’ region of 16S mitochondrial rRNA genes of different kinds of fishes. The primers were successfully used to amplify an expected product fragment of about 1.2 kb from various marine fish species, and the .. Read More»
- Genet. Mol. Res. 12(4):
- 2013.October.15.6
- DOI:
- 10.4238/2013.October.15.6
Molecular cloning, sequence characterization, and gene expression profiling of a novel water buffalo (Bubalus bubalis) gene, AGPAT6
Authors: S. Song, J.L. Huo,D.L. Li, Y.Y. Yuan, F. Yuan and Y.W. Miao
Several 1-acylglycerol-3-phosphate-O-acyltransferases (AGPATs) can acylate lysophosphatidic acid to produce phosphatidic acid. Of the eight AGPAT isoforms, AGPAT6 is a crucial enzyme for glycerolipids and triacylglycerol biosynthesis in some mammalian tissues. We amplified and identified the complete coding sequence (CDS) of the water buffalo AGPAT6 gene .. Read More»
- Genet. Mol. Res. 12(4):
- 2013.October.1.2
- DOI:
- 10.4238/2013.October.1.2
Expression profile of insulin-like growth factor system genes in muscle tissues during the postnatal development growth stage in ducks
Authors: C.-L. Song, H.-H. Liu, J. Kou, L. Lv, L. Li, W.-X. Wang and J.-W. Wang
Insulin-like growth factors (IGFs) are regulators that modulate the proliferation and differentiation of muscle tissues. We quantified the messenger RNA (mRNA) expression of IGF-I, IGF-II, and type I and II IGF receptors (IGF-IR and IGF-IIR) in muscle tissues including the breast, leg, and myocardium during an early postnatal development growth stage (pos.. Read More»
- Genet. Mol. Res. 12(4):
- 2013.May.6.3
- DOI:
- 10.4238/2013.May.6.3
Phylogenetic classification and clinical aspects of a new putative Deltapapillomavirus associated with skin lesions in cattle
Authors: T.C. Melo, R.F. Carvalho, J. Mazzucchelli-de-Souza, N. Diniz, S. Vasconcelos, S.L.M.R. Assaf, R.P. Araldi, R.M. Ruiz, I. Kerkis, W. Be�§ak and R.C. Stocc
Bovine papillomaviruses (BPVs) are recognized as causal agents of benign and malignant tumors in cattle. Thirteen types of BPVs have already been described and classified into 3 distinct genera. Divergences in the nucleotide sequence of the L1 gene are used to identify new viral types through the employment of PCR assays with .. Read More»
- Genet. Mol. Res. 13(2):
- 2014.April.3.18
- DOI:
- 10.4238/2014.April.3.18
RUNX2 mutations in cleidocranial dysplasia
Authors: K.-E. Lee1, F. Seymen2, J. Ko1, M. Yildirim2, E.B. Tuna2, K. Gencay2 and J.-W. Kim1,3
The runt-related transcription factor 2 gene (RUNX2), which is also known as CBFA1, is a master regulatory gene in bone formation. Mutations in RUNX2 have been identified in cleidocranial dysplasia (CCD) patients. CCD is a rare autosomal dominant skeletal dysplasia that is characterized by delayed closure of cranial sutures, aplastic or hypoplastic clavic.. Read More»
- Genet. Mol. Res. 12(4):
- 2013.October.15.5
- DOI:
- 10.4238/2013.October.15.5
Improving yield and quality traits of durum wheat by introgressing chromosome segments from hexaploid wheat
Authors: Improving yield and quality traits of durum wheat by introgressing chromosome segments from hexaploid wheat
Durum wheat (Triticum turgidum durum; 2n = 4x = 28; genome AABB) has long been an important food resource for human diets. The projected increase of the world’s population to 9.1 billion by 2050 has highlighted the importance and urgency for improving the yield and quality performance of durum wheat. A backcrossed popula.. Read More»
- Genet. Mol. Res. 12(4):
- 2013.December.2.9
- DOI:
- 10.4238/2013.December.2.9
Lack of association between Cyclin D1 gene G870A polymorphism and esophageal cancer: evidence from a meta-analysis
Authors: W. Cai, Z.T. Wang, J. Zhong and Y. Zhang
The association between the Cyclin D1 gene (CCND1) G870A polymorphism and esophageal cancer has been widely evaluated, with conflicting results. As meta-analysis is a reliable approach to resolving discrepancies, we aimed to evaluate this association. Data were available from 9 study populations incorporating 1898 cases and 3046 controls. Overall, the all.. Read More»
- Genet. Mol. Res. 12(4):
- 2013.April.26.1
- DOI:
- 10.4238/2013.April.26.1