Animal Genetics
The kinin B2 receptor gene structure, product processing and expression in adult and fetal rats: evidence for gene evolution
Authors: C.E. Fran�§a, C.F. Vicari, A.M. Piza, E.A. Geroldo, M.L. Be�§ak, W. Be�§ak, R.C. Stocco and C.J. Lindsey
We examined the structure of the rat kinin B2 receptor gene (KB2r) and encoding messenger RNA (mRNA) processing. Differently from the closely related mouse and rabbit genes that have three exons and two introns, the rat gene purportedly consists of four exons and three introns. There are two purported gene products; one of the.. Read More»
- Genet. Mol. Res. 9(1):
- vol9-1gmr681
- DOI:
- 10.4238/vol9-1gmr681
Genetic relationship between the Nordestino horse and national and international horse breeds
Authors: D.A.F. Pires, E.G.A. Coelho, J.B. Melo, D.A.A. Oliveira, M.N. Ribeiro, E. Gus Cothran and R. Juras
Knowledge of genetic diversity and relationships between breeds is very important for conservation programs. Hair samples were collected from 393 individual Nordestino horses and genotyped using 14 microsatellite markers in order to investigate the genetic relationship between this breed and 66 international horse breeds. Ther.. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15027881
- DOI:
- 10.4238/gmr.15027881
Chicken skeletal muscle-associated macroarray for gene discovery
Authors: E.C. Jorge, C.M.R. Melo, M.F. Ros�¡rio, J.R.S. Rossi, M.C. Ledur, A.S.A.M.T. Moura and L.L. Coutinho
Macro- and microarrays are well-established technologies to determine gene functions through repeated measurements of transcript abundance. We constructed a chicken skeletal muscle-associated array based on a muscle-specific EST database, which was used to generate a tissue expression dataset of ~4500 chicken genes across 5 ad.. Read More»
- Genet. Mol. Res. 9(1):
- vol9-1gmr712
- DOI:
- 10.4238/vol9-1gmr712
Additive genetic relationship of longevity with fertility and production traits in Nellore cattle based on bivariate models
Authors: M.H. Van Melis, H.N. Oliveira, J.P. Eler, J.B.S. Ferraz, J. Casellas and L. Varona
Survival or longevity is an economically important trait in beef cattle. The main inconvenience for its inclusion in selection criteria is delayed recording of phenotypic data and the high computational demand for including survival in proportional hazard models. Thus, identification of a longevity-correlated trait that could .. Read More»
- Genet. Mol. Res. 9(1):
- vol9-1gmr710
- DOI:
- 10.4238/vol9-1gmr710
Caspase-3/-8/-9, Bax and Bcl-2 expression in the cerebellum, lymph nodes and leukocytes of dogs naturally infected with canine distemper virus
Authors: H.L. Del Puerto, A.S. Martins, L. Moro, A. Milsted, F. Alves, G.F. Braz and A.C. Vasconcelos
Canine distemper is an immunosuppressive disease caused by the canine distemper virus (CDV). Pathogenesis mainly involves the central nervous system and immunosuppression. Dogs naturally infected with CDV develop apoptotic cells in lymphoid tissues and the cerebellum, but this apoptotic mechanism is not well characterized. To .. Read More»
- Genet. Mol. Res. 9(1):
- vol9-1gmr717
- DOI:
- 10.4238/vol9-1gmr717
Polymorphisms in the LPL gene and their association with growth traits in Jiaxian cattle
Authors: L.S. Gui, Y.M. Huang, J.Y. Hong and L.S. Zan
Previous studies showed that the lipoprotein lipase (LPL) gene was involved in metabolism and transport of lipids, suggesting that the LPL is a potential candidate gene affecting growth traits in animals. The aim of this study was to identify polymorphism in the bovine LPL gene and analyze its possible association with growth .. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15027590
- DOI:
- 10.4238/gmr.15027590
Adaptive evolution of the mitochondrial ND6 gene in the domestic horse
Authors: T. Ning, H. Xiao, J. Li, S. Hua and Y.P. Zhang
Mitochondria play a crucial role in energy metabolism through oxidative phosphorylation. Organisms living at high altitudes are potentially influenced by oxygen deficits and cold temperatures. The severe environmental conditions can impact on metabolism and direct selection of mitochondrial DNA. As a wide-ranging animal, the d.. Read More»
- Genet. Mol. Res. 9(1):
- vol9-1gmr705
- DOI:
- 10.4238/vol9-1gmr705
Interactions of allele E of the MC1R gene with FM and mutations in the MLPH gene cause the five-gray phenotype in the Anyi tile-like gray chicken
Authors: J.G. Xu, M.G. Xie, S.Y. Zou, X.F. Liu, X.H. Li1, J.F. Xie and X.Q. Zhang
The Anyi tile-like gray chicken is a Chinese indigenous breed with a gray dilution phenotype, having gray feathers, comb, skin, shanks, and beak, which is valuable for genetic research on pigmentation. However, the genetic basis of the gray dilution phenotype remains unknown. The objective of this study was to investigate the .. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15027633
- DOI:
- 10.4238/gmr.15027633
Microarray analysis of differentially expressed genes in the liver between Bai�er layers and broilers
Authors: Q.-G. Wang , H.-F. Zhang, S.-Z. Wang, G.L. Gao, L. Leng, W. Na and H. Li
In this study, we profiled gene expression in chicken liver and screened differentially expressed genes in the Bai’er layers and fat line broilers. Birds were derived from the 14th generation of Northeast Agricultural University fat broiler lines and Bai’er layers. Chicken genome arrays were used to screen differentially expressed genes in liv.. Read More»
- Genet. Mol. Res. 14(1):
- 2015.March.31.19
- DOI:
- 10.4238/2015.March.31.19
Diagnosis and epidemiology of canine leishmaniasis in southeastern Bahia, Brazil
Authors: T.N.A. Oliveira, P.E.B. Guedes, G.B. Souza, F.S. Carvalho, R.S. Alberto Carlos G.R. Albuquerque, A.D. Munhoz and F.L. Silva
Leishmaniasis is a disease caused by protozoa of the genus Leishmania. Two distinct forms are recognized: visceral leishmaniasis (VL) and cutaneous leishmaniasis (CL). In the Americas, the causative agent of VL is L. infantum chagasi, whereas L. braziliensis is principally responsible for CL. Domestic dogs constitute the main .. Read More»
- Genet. Mol. Res. 15(3):
- gmr.15038684
- DOI:
- 10.4238/gmr.15038684