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Effect of bradykinin on renal mesangial cell proliferation and extracellular matrix secretion
Authors: C.Y. Liu, L.L. Zhou, Q. Cheng, S.N. Jiang, J. Sheng, J.D. Sun and J.Y. Zhao
Recent studies have found that bradykinin (BK) plays a role in delaying glomerulosclerosis, although the mechanism of this phenomenon remains unclear. Mesangial cell proliferation (MCP) and extracellular matrix (ECM) secretion are important mechanisms for glomerulosclerosis. This study investigated the impact of BK on the plat.. Read More»
- Genet. Mol. Res. 13(1):
- http://dx.doi.org/2014.January.21.18
- DOI:
- http://dx.doi.org/10.4238/2014.January.21.18
Low prevalence of glucokinase gene mutations in gestational diabetic patients with good glycemic control
Authors: H.R. Frigeri, I.C.R. Santos, R.R. R�?©a, A.C.R. Almeida, C.M.T. Fadel-Picheth, F.O. Pedrosa, E.M. Souza, F.G.M. Rego and G. Picheth
Glucokinase (GCK) plays a key role in glucose homeostasis. Gestational diabetes mellitus increases the risk of gestational complications in pregnant women and fetuses. We screened for mutations in coding and flanking regions of the GCK gene in pregnant women with or without gestational diabetes in a Brazilian population. A sam.. Read More»
- Genet. Mol. Res. 11(2):
- 2012.May.18.2
- DOI:
- 10.4238/2012.May.18.2
Genetic parameters and path analysis in cowpea genotypes grown in the Cerrado/Pantanal ecotone
Authors: K.V. Lopes, P.E. Teodoro, F.A. Silva, M.T. Silva, R.L. Fernandes,T.C. Rodrigues, T.C. Faria and A.M. Corr�?ªa
Estimating genetic parameters in plant breeding allows us to know the population potential for selecting and designing strategies that can maximize the achievement of superior genotypes. The objective of this study was to evaluate the genetic potential of a population of 20 cowpea genotypes by estimating genetic parameters and.. Read More»
- Genet. Mol. Res. 16(2):
- gmr16029559
- DOI:
- 10.4238/gmr16029559
Comparative transcriptome analysis of self-incompatible flower stigmas and self-compatible bud stigmas following self-pollination in broccoliComparative transcriptome analysis of self-incompatible flower stigmas and self-compatible bud stigmas followingself-pollination in broccoli
Authors: H.F. Yu, J.S. Wang, X.G. Sheng, Z.Q. Zhao, Z.R. Qi H.H. Gu
DH07 is a DH line of Class I S-haplotype in broccoli (Brassica oleracea var. italica), in which stigmas of flowers show self-incompatibility (SI) and stigmas of buds show self-compatibility (SC). The molecular mechanisms that lead to stigmas at different developmental stages having different responses to self-pollination are y.. Read More»
- Genet. Mol. Res. 16(1):
- gmr16019018
- DOI:
- 10.4238/gmr16019018
Molecular detection by analysis of the 16S rRNA gene of fecal coliform bacteria from the two Korean Apodemus species (Apodemus agrarius and A. peninsulae)
Authors: M.M. Rahman, K.B. Yoon, S.J. Lim, M.G. Jeon, H.J. Kim, H.Y. Kim, J.Y. Cho, H.M. Chae and Y.C. Park
Wild mouse feces can disseminate zoonotic microorganisms throughout a farm, which is a great threat to human health and can lead to economic loss through contaminated agricultural produce. To assess the microbial communities, especially fecal coliform bacteria, we used two methods. First, we isolated bacterial colonies onto th.. Read More»
- Genet. Mol. Res. 16(2):
- gmr16029510
- DOI:
- 10.4238/gmr16029510
Association of a CYP4A11 polymorphism and hypertension in the Mongolian and Han populations of China
Authors: J.Q. Liang, M.R. Yan, L. Yang, Q. Suyila, H.W. Cui and X.L. Su
Human cytochrome P450 4A11 (CYP4A11) plays a role in the regulation of blood pressure through the conversion of arachidonic acid into 20-hydroxyeicosatetraenoic acid (20-HETE). We therefore investigated the association between a CYP4A11 polymorphism (rs9333025) with hypertension in the Mongolian and Han ethnic groups. We studi.. Read More»
- Genet. Mol. Res. 13(1):
- 2014.January.21.20
- DOI:
- 10.4238/2014.January.21.20
Significant association between the MTHFR A1298C polymorphism and hepatocellular carcinoma risk: a meta-analysis
Authors: W. Chang, Q. Meng, J.H. Liu, L.X. Wu, Y. Chen,S.D. Chen
The A1298C polymorphism of the methylenetetrahydrofolate reductase (MTHFR) gene has been reported to be associated with hepatocellular carcinoma (HCC), but there are conflicting results from previous studies. The present study aimed to investigate the association between this polymorphism and the risk of HCC using a meta-analy.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.7.9
- DOI:
- 10.4238/2015.December.7.9
LAMP-PCR detection of ochratoxigenic Aspergillus species collected from peanut kernel
Authors: H.M. Al-Sheikh
Over the last decade, ochratoxin A (OTA) has been widely described and is ubiquitous in several agricultural products. Ochratoxins represent the second-most important mycotoxin group after aflatoxins. A total of 34 samples were surveyed from 3 locations, including Mecca, Madina, and Riyadh, Saudi Arabia, during 2012. Fungal contamination frequency was det.. Read More»
- Genet. Mol. Res. 14(1):
- 2015.January.30.5
- DOI:
- 10.4238/2015.January.30.5
Genetic gains in the UENF-14 popcorn population with recurrent selection
Authors: I.L.J. Freitas, A.T. do Amaral J�?ºnior, S.P. Freitas Jr., P.D.S. Cabral, R.M. Ribeiro and L.S.A. Gon�?§alves
The popcorn breeding program of Universidade Estadual do Norte Fluminense Darcy Ribeiro aims to provide farmers a cultivar with desirable agronomic traits, particularly with respect to grain yield (GY) and popping expansion (PE). We evaluated full-sib families from the seventh cycle of recurrent selection and estimated the gen.. Read More»
- Genet. Mol. Res. 13(1):
- 2014.January.21.21
- DOI:
- 10.4238/2014.January.21.21
Changes of circulating CD4+CD25+CD127low regulatory T cells in patients with acute coronary syndrome and its significance
Authors: M. Liu, L.-J. Xu, J.-X. Wu
The aim of this study was to investigate the changes of circulating CD4+CD25+CD127low regulatory T cells (Treg) in patients with acute coronary syndrome (ACS) and its significance. The experiment was divided into three groups: ACS (48 patients), stable angina pectoris (SAP) (24 patients), and normal controls (24 subjects). The.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.7.4
- DOI:
- 10.4238/2015.December.7.4