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Development and characterization of single nucleotide polymorphism markers in Camellia sinensis (Theaceae)
Authors: C.C. Zhang, L.Y. Wang, K. Wei and H. Cheng
Tea is the second most popular non-alcoholic beverage in the world. In recent years, several molecular markers have been used in genetic studies of the tea plant. Yet, only a few single nucleotide polymorphisms (SNPs) have been reported. Here, we identified 818 putative SNPs from expressed sequence tag (EST) databases for the .. Read More»
- Genet. Mol. Res. 13(3):
- 2014.April.14.10
- DOI:
- 10.4238/2014.April.14.10
Clinical significance of combined liver function and high-sensitivity C-reactive protein measurement in children with hand-foot-mouth disease
Authors: F.X. Han, J.H. Gao and J.H. Gai
Hand-foot-mouth disease (HFMD) is a common pediatric disease responsible for the development of rashes or herpes on the hand, foot, and mouth. Severe complications of HFMD include myocarditis, pulmonary edema, aseptic meningoencephalitis, and even death. Therefore, early diagnosis of HFMD is of particular importance. In this study, we determined the clini.. Read More»
- Genet. Mol. Res. 15(3):
- gmr.15038744
- DOI:
- 10.4238/gmr.15038744
Analysis of genetic diversity and trait correlations among Korean landrace rice (Oryza sativa L.)
Authors: F.P. Li, Y.S. Lee, S.W. Kwon, G. Li and Y.J. Park
This study analyzed 394 Korean rice landrace accessions, including 93 waxy varieties, for polymorphisms using 29 simple sequence repeat (SSR) markers. In total, 381 alleles served as raw data for estimating the genetic diversity (GD) and population structure. The number of alleles per locus ranged from 3 to 44 (average = 13.14.. Read More»
- Genet. Mol. Res. 13(3):
- 2014.April.14.12
- DOI:
- 10.4238/2014.April.14.12
Clinical value of detection of immune index and inflammatory reaction changes in patients with autoimmune disease
Authors: X.J. Zhang, H.Y. Zhou and Y. Li
Previous studies have shown a close correlation between the generation of B cell autoantibodies and imbalances in T lymphocyte subpopulations and the occurrence of disease. In this study, we have analyzed the effects of abnormal expression of CD4+CD25+-regulatory T cells, T lymphocyte subpopulations, immunoglobulins, complement factors, inflammatory facto.. Read More»
- Genet. Mol. Res. 15(3):
- gmr.15038745
- DOI:
- 10.4238/gmr.15038745
Establishment of cytochrome P450 3A4 and glutathione S-transferase A1-transfected human hepatoma cell line and functional analysis
Authors: B.X. Chang, S.L. You, H.L. Liu, P.Y. Mao and S.J. Xin
This study aimed to enhance the drug metabolism function of the human hepatoma cell line C3A and to explore the related significance for patients with severe liver disease. The important liver phase I and phase II drug metabolism enzymes, cytochrome P450 3A4 (CYP 3A4) and glutathione S-transferase A1 (GST A1), were constructed.. Read More»
- Genet. Mol. Res. 13(3):
- 2014.April.14.11
- DOI:
- 10.4238/2014.April.14.11
Direct sequencing of mutations in the copper-transporting P-type adenosine triphosphate (ATP7B) gene for diagnosis and pathogenesis of Wilson�s disease
Authors: D.F. Zhang and J.F. Teng
Copper-transporting P-type adenosine triphosphatase (ATP7B) has been identified as the pathogenic gene in hepatolenticular degeneration, or Wilson’s disease (WD). The aim of this study was to explore the correlation between genetic mutations and the clinical profile of WD, and to discuss the value of mutation examination in its diagnosis for providi.. Read More»
- Genet. Mol. Res. 15(3):
- gmr.15038746
- DOI:
- 10.4238/gmr.15038746
Enhancement of pectinase production by ultraviolet irradiation and diethyl sulfate mutagenesis of a Fusarium oxysporum isolate
Authors: L.B. Yin, C.F. Zhang, Q.L. Xia, Y. Yang, K. Xiao and L.Z. Zhao
Fusarium oxysporum strain BM-201 was treated with ultraviolet (UV) radiation to obtain a high pectinase-producing strain. Mutant UV-10-41 was obtained and then treated by diethyl sulfate. Next, the mutant UV-diethyl sulfate-43 derived from UV-10-41 was selected as high pectinase-producing strain. Mutant UV-diethyl sulfate-43 was incubated on slant for 10 .. Read More»
- Genet. Mol. Res. 15(3):
- gmr.15038986
- DOI:
- 10.4238/gmr.15038986
Prominent contribution of Th1, Th17, and Tregs to the host response during M. neoaurum infection
Authors: C.F. Wang, W.T. Yang, L.M. Yue, J.Y. Qiu, L.J. Zhang, C. Wang, X.Y. Jiang and A.D. Qian
Nontuberculous mycobacteria are ubiquitous in outside environment and animals. As for nontuberculous mycobacteria infection, there is only limited information in humans regarding infection and the subsequent immune response, especially for Mycobacterium neoaurum. Here, haematoxylin-eosin and Ziehl-Neelsen staining were used to observe pathological changes.. Read More»
- Genet. Mol. Res. 15(3):
- gmr.15038989
- DOI:
- 10.4238/gmr.15038989
Sexual reproduction development in apomictic Eulaliopsis binata (Poaceae)
Authors: J.J. Li, L. Liu, Y.D. Ouyang and J.L. Yao
Apomixis is a particular mode of reproduction that allows progeny formation without meiosis and fertilization. Eulaliopsis binata, a tetraploid apomictic species, is widely used for making paper, rope and mats. There is great potential for fixation of heterosis in E. binata due to autonomous endosperm formation in this species. Although most of its embryo sa.. Read More»
- Genet. Mol. Res. 10(4):
- 2011.October.5.3
- DOI:
- 10.4238/2011.October.5.3
Use of bone mesenchymal stem cells to treat rats with acute liver failure
Authors: S.F. Yuan, T. Jiang, L.H. Sun, R.J. Zheng, G.Q. Cao, N.Z. Ahat and Y.X. Zhang
This study aimed to isolate mesenchymal stem cells from bone mesenchymal stem cells (BMSCs), determine their therapeutic potential for treating rats with acute liver failure (ALF), further explore the factors that induce liver failure mechanisms, and elucidate the role of bone marrow stem cell therapy and BMSCs on liver homing.. Read More»
- Genet. Mol. Res. 13(3):
- 2014.April.30.10
- DOI:
- 10.4238/2014.April.30.10