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Immunomodulatory effect of bone marrow mesenchymal stem cells on T lymphocytes in patients with decompensated liver cirrhosis
Authors: C.H. Guo, L.X. Han, M.R. Wan, G.J. Deng and J.H. Gan
We explored the immunomodulatory effects of bone marrow mesenchymal stem cells (BMSCs) on peripheral blood T lymphocytes in patients with decompensation stage, hepatitis B-associated cirrhosis. MSCs from nine patients were analyzed by flow cytometry. Peripheral blood lymphocytes were isolated for fluorescent staining. Following stimulation by phytohemaggl.. Read More»
- Genet. Mol. Res. 14(2):
- 2015.June.26.13
- DOI:
- 10.4238/2015.June.26.13
Paeonia (Paeoniaceae) expressed sequence tag-derived microsatellite markers transferred to Paeonia delavayi
Authors: D.X. Wang, H. Ma, Y.L. Zhang, A.A. Duan, W.J. Li and Z.H. Li
Paeonia Franchet contains approximately 30 species of perennial herbs and is the only member of the family Paeoniaceae. Paeonia delavayi is an endangered ornamental plant that has a compound flower color and is endemic to southwest China. Its optimal habitats have been fragmented and its population size has greatly decreased as a result of human activitie.. Read More»
- Genet. Mol. Res. 12(2):
- 2013.April.17.6
- DOI:
- 10.4238/2013.April.17.6
Genome-wide identification and phylogenetic analysis of the AP2/ERF gene superfamily in sweet orange (Citrus sinensis)
Authors: T.M. Ito, P.B. Polido, M.C. Rampim, G. Kaschuk and S.G.H. Souza
Sweet orange (Citrus sinensis) plays an important role in the economy of more than 140 countries, but it is grown in areas with intermittent stressful soil and climatic conditions. The stress tolerance could be addressed by manipulating the ethylene response factor (ERF) transcription factors because they orchestrate .. Read More»
- Genet. Mol. Res. 13(3):
- 2014.September.26.22
- DOI:
- 10.4238/2014.September.26.22
miR-204 suppresses non-small-cell lung carcinoma (NSCLC) invasion and migration by targeting JAK2
Authors: P. Wang, H.Y. Lv, D.M. Zhou and E.N. Zhang
Aberrant expression of microRNA is associated with the development and progression of cancers. MicroRNA-204 (miR-204) down-regulation has been previously demonstrated in non-small-cell lung carcinoma (NSCLC); however, the underlying mechanism by which miR-204 suppresses tumorigenesis in NSCLC remains elusive. In this study, mi.. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15026415
- DOI:
- 10.4238/gmr.15026415
Estimate of genetic gain in popcorn after cycles of phenotypic recurrent selection
Authors: H.J. Ematn�©, J.A.R. Nunes, K.O.G. Dias, P.E.R. Prado and J.C. Souza
Popcorn is widely consumed in Brazil, yet there are few breeding programs for this crop. Recurrent selection (RS) is a viable breeding alternative for popcorn; however, the gains achieved must be frequently checked. The aim of this study was to assess the effect of selection for grain type (round and pointed) after four cycles.. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15026860
- DOI:
- 10.4238/gmr.15026860
Phenotypic and genotypic variation among Capsicum annuum recombinant inbred lines resistant to bacterial spot
Authors: S.O. Moreira, R. Rodrigues, H.S. Oliveira, A.M. Medeiros, C.P. Sudr�© and L.S.A. Gon�§alves
A breeding program carried out under Brazilian growing conditions to obtain Capsicum annuum cultivars with disease resistance to bacterial spot (BS) produced 8 promising recombinant inbred lines (RILs). The present study aimed to characterize these RILs using phenotypic descriptors and molecular markers (inter-simple sequence repeat) and to confirm their .. Read More»
- Genet. Mol. Res. 12(2):
- 2013.April.17.2
- DOI:
- 10.4238/2013.April.17.2
A novel variant of the �²-lactamase ADC-61 gene in multi-drug resistant Acinetobacter baumannii
Authors: Y. Zhou, S.-J. Teng, L. Yang, S.-B. Li and Y. Xu
The aim of this study was to investigate the existence of a β-lactamase gene in a group of multi-drug resistant Acinetobacter baumannii. Twenty strains of multi-drug resistant A. baumannii were isolated. Thirty-four β-lactamase genes and the ISaba1- OXA-23 linkage were analyzed in these strains by polymerase chain reaction (PCR) and verified by .. Read More»
- Genet. Mol. Res. 14(2):
- 2015.June.29.2
- DOI:
- 10.4238/2015.June.29.2
Cassava interspecific hybrids with increased protein content and improved amino acid profiles
Authors: P.T.C. Gomes and N.M.A. Nassar
Cassava (Manihot esculenta) is a principal food for large populations of poor people in the tropics and subtropics. Its edible roots are poor in protein and lack several essential amino acids. Interspecific hybrids may acquire high protein characteristics from wild species. We analyzed 19 hybrids of M. esculenta with its wild relative, M. oligantha, for c.. Read More»
- Genet. Mol. Res. 12(2):
- 2013.April.12.8
- DOI:
- 10.4238/2013.April.12.8
Genetic diversity in wild Dipsacus chinensis populations from China based on ISSR markers
Authors: D.-X. Chen, L.-Y. Li, X. Zhang, Y. Wang and Z. Zhang
Wild Dipsacus chinensis plants in China have become endangered owing to over-harvesting and habitat fragmentation. We examined the genetic diversity and genetic structure of 90 individuals from three populations using inter-simple sequence repeat markers and found that 106 of 173 bands amplified by 22 informative and reliable primers were polymorphic. The.. Read More»
- Genet. Mol. Res. 12(2):
- 2013.April.12.7
- DOI:
- 10.4238/2013.April.12.7
Changes in growth factor levels in the cerebrospinal fluid of autism patients after transplantation of human umbilical cord blood mononuclear cells and umbilical cord-derived mesenchymal stem cells
Authors: Q. Li, C.-F. Chen, D.-Y. Wang, Y.-T. L�¼, Y. Huan, S.-X. Fang,Y. Han, R.-C. Ge and X.-W. Ch
-.. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15027526
- DOI:
- 10.4238/gmr.15027526