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Antibacterial activity of leaf extract of Breonadia salicina (Rubiaceae), an endangered medicinal plant of Saudi Arabia
Authors: F. Al-Qurainy, Abdel-Rhman Z. Gaafar, S. Khan, M. Nadeem, M. Tarroum, A. Alaklabi and J. Thomas
Wild plants can contain bioactive compounds with potential activity against disease-causing microorganisms. In the Kingdom of Saudi Arabia, there are many plant species that may have antibacterial, antifungal, or antiviral activities, among other properties. We extracted bioactive compounds with methanol as well as with water from leaves of Breonadia sali.. Read More»
- Genet. Mol. Res. 12(3):
- 2013.August.29.5
- DOI:
- 10.4238/2013.August.29.5
Analysis of correlations between coronary heart disease and haplotypes of the angiotensin II receptor type 1 (AGTR1) gene
Authors: L.J. Duan and X.D. Wang
This study aimed to explore correlations between haplotypes of the angiotensin II receptor type 1 (AGTR1) gene and coronary heart disease (CHD). In total, 204 patients with CHD and 206 healthy controls were genotyped using denaturing high-performance liquid chromatography between 2008 and 2014. Five polymorphic loci were found.. Read More»
- Genet. Mol. Res. 15(1):
- gmr.15017457
- DOI:
- 10.4238/gmr.15017457
Molecular evolution of the melanocortin 1-receptor pigmentation gene in rodents
Authors: G.L. Gon�§alves, V.R. Paix�£o-C�´rtes and T.R.O. Freitas
Adaptive variation in the melanocortin 1-receptor gene (MC1R), a key locus in melanogenesis, has been identified in some species of rodents. However, in others, MC1R has no causative role in pigmentation phenotypes despite their coat color variation. In this study, we characterized the rates and patterns of MC1R nucleotide and amino acid sequence evolutio.. Read More»
- Genet. Mol. Res. 12(3):
- 2013.February.28.24
- DOI:
- 10.4238/2013.February.28.24
Abnormal hemoglobin phenotypes in carriers of mild anemia in Latin America
Authors: P.J.A. Zamaro and C.R. Bonini-Domingos
We looked for abnormal hemoglobins in blood samples sent for diagnosis of anemia. Identification of the hemoglobins was made using electrophoretic, chromatographic and molecular procedures. The 2020 blood samples were of patients from various regions of Brazil and from some other Latin American countries. Among the abnormal he.. Read More»
- Genet. Mol. Res. 9(1):
- vol9-1gmr721
- DOI:
- 10.4238/vol9-1gmr721
Efficient human paternity testing with a panel of 40 short insertion-deletion polymorphisms
Authors: J.R. Pimenta and S.D.J. Pena
We developed a panel of 40 multiplexed short insertion-deletion (indel) polymorphic loci with widespread chromosomal locations and allele frequencies close to 0.50 in the European population. We genotyped these markers in 360 unrelated self-classified White Brazilians and 50 mother-child-probable father trios with proven pater.. Read More»
- Genet. Mol. Res. 9(1):
- vol9-1gmr838
- DOI:
- 10.4238/vol9-1gmr838
Genetic characterization of pea (Pisum sativum) germplasm from Turkey using morphological and SSR markers
Authors: G. Sar�±kam�±��, R. Yanmaz, S. Ermi��, M. Bak�±r and C. Y�¼ksel
The need for the conservation of plant genetic resources has been widely accepted. Germplasm characterization and evaluation yield information for more efficient utilization of these valuable resources. The aim of the present study was to characterize the pea germplasm conserved at the Aegean Agricultural Research Institute of.. Read More»
- Genet. Mol. Res. 9(1):
- vol9-1gmr762
- DOI:
- 10.4238/vol9-1gmr762
Artificial intelligence in the selection of common bean genotypes with high phenotypic stability
Authors: A.M. Corr�ªa, P.E. Teodoro, M.C. Gon�§alves, L.M.A. Barroso,M. Nascimento, A. Santos and F.E. Torres
Artificial neural networks have been used for various purposes in plant breeding, including use in the investigation of genotype x environment interactions. The aim of this study was to use artificial neural networks in the selection of common bean genotypes with high phenotypic adaptability and stability, and to verify their .. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15028230
- DOI:
- 10.4238/gmr.15028230
Association of the programmed cell death-1 PD1.5 C>T polymorphism with cervical cancer risk in a Chinese population
Authors: X.F. Li, X.Q. Jiang, J.W. Zhang and Y.J. Jia
The association of the programmed cell death-1 PD1.5 C>T polymorphism with cervical cancer risk has not been investigated. In this hospital-based case-control study, we analyzed 256 patients with cervical cancer and 250 healthy controls. Pearson chi-square test was used to examine differences in the distribution of genotype.. Read More»
- Genet. Mol. Res. 15(1):
- gmr.15016357
- DOI:
- 10.4238/gmr.15016357
Cloning and molecular characterization of a cDNA encoding a small GTPase from Hevea brasiliensis
Authors: H.L. Li, D. Guo, W.M. Tian and S.Q. Peng
Small GTPases play a critical role in the regulation of a range of cellular processes including growth, differentiation, and intracellular transportation. The cDNA encoding a small GTPase, designated as HbGTPase1, was isolated from Hevea brasiliensis. HbGTPase1 was 882 bp long containing a 612-bp open reading frame encoding a putative protein of 203 amino.. Read More»
- Genet. Mol. Res. 12(3):
- 2013.September.3.7
- DOI:
- 10.4238/2013.September.3.7
Genetic variation in WDR1 is associated with gout risk and gout-related metabolic indices in the Han Chinese population
Authors: L.J. Liu, X.Y. Zhang, N. He K Liu, X.G. Shi, T. Feng, T.T. Geng, D.Y. Yuan, L.L. Kangand T.B. Jin
Gout is the most common form of inflammatory arthritis affecting men, and current evidence suggests that genetic factors contribute to its progression. As a previous study identified that WD40 repeat protein 1 (WDR1) is associated with gout in populations of European descent, we sought to investigate its relationship with this.. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15027381
- DOI:
- 10.4238/gmr.15027381