Se
Drosha, DGCR8, and Dicer mRNAs are downregulated in human cells infected with dengue virus 4 - Genet. Mol. Res. 15 (2): gmr.15027891 Drosha, Dicer, and TRBP mRNA are downregulated in Vero cells with the 3 UTR of Dengue virus
Authors: J.A. Castillo and S. Urcuqui-Inchima
A recent paper (Casseb et al., 2016) published in the journal Genetics and Molecular Research described the interesting concept that dengue virus (DENV)-4 infection, in the human cell line A-549, leads to the downregulation of expression of key components of microRNA (miRNA) biogenesis, such as Drosha, Dicer, and DGCR8. For th.. Read More»
- Genet. Mol. Res. 15(3):
- gmr.15039050
- DOI:
- 10.4238/gmr.15039050
Genomic selection of seed weight based on low-density SCAR markers in soybean
Authors: Y.J. Shu, D.S. Yu, D. Wang, X. Bai, Y.M. Zhu and C.H. Guo
With the development of molecular marker technology, crop breeding has been accelerated by marker-assisted selection for the improvement of quantitative traits. However, due to the traits’ polygenic nature, traditional marker-assisted selection methods are ill-suited for identification of quantitative trait loci. Genomic selection (GS) was introduce.. Read More»
- Genet. Mol. Res. 12(3):
- 2013.July.3.2
- DOI:
- 10.4238/2013.July.3.2
Bulk segregant analysis (BSA) for improving cold stress resistance in maize using SSR markers
Authors: M.Q.U. Farooqi, K.J. Sa, T.K. Hong and J.K. Lee
In this study, eight inbred maize lines with high or low tolerance to cold temperature were investigated using bulk segregant analysis (BSA). Genetic diversity and genetic relationships were investigated using 100 simple sequence repeat (SSR) markers linked to cold tolerance in maize. A total of 319 alleles were identified. Am.. Read More»
- Genet. Mol. Res. 15(4):
- gmr15049326
- DOI:
- 10.4238/gmr15049326
Effect of miR-29c and miR-129-5p on epithelial-mesenchymal transition in experimental biliary atresia mouse models
Authors: J.Y. Wang, Z.H. Li, M. Ye, Q. Feng, Z.M. Chen, X.S. Ye, Z.G. Wu, B. Wang, L. Liu and J. Yao
Biliary atresia (BA) is a destructive bile duct disease occurring in newborn children within a few weeks after birth. In this study, the effect of miR-29c and miR-129-5p on epithelial-mesenchymal transition (EMT) in experimental BA was explored by constructing BA mouse models via Rhesus rotavirus vaccine infection. miR-29c and.. Read More»
- Genet. Mol. Res. 15(3):
- gmr.15037753
- DOI:
- 10.4238/gmr.15037753
Genomic variability of Pantoea ananatis in maize white spot lesions assessed by AFLP markers
Authors: A.M. Miller, J.E.F. Figueiredo, C.L. Chaves, E.A. Ruas, M.I. Balbi-Pe�?±a, N.B. Colauto and L.D. Paccola-Meirelles
Measures to control maize white spot (MWS) caused by Pantoea ananatis are preferentially based on resistant cultivars. A lack of knowledge on the genetic variability of pathogens could interfere with the development and utilization of controlling strategies in this pathosystem. The main goals of this study were to investigate .. Read More»
- Genet. Mol. Res. 15(4):
- gmr15049452
- DOI:
- 10.4238/gmr15049452
Genetic variability affecting Exserohilum turcicum resistance in popcorn lines grown under high and low phosphorus conditions
Authors: A.T. Amaral Jr., R.M. Ribeiro, P.H.D. Santos, T.P.S. Poltronieri, J.M.S. Vivas, I.F.S. Gerhardt, B.M. Carvalho, C.S. Freitas and S.B. Miranda
Northern leaf blight (NLB), caused by Exserohilum turcicum, is one of the main foliar diseases that affect popcorn culture. Farmers use many control measures to minimize damage caused by this disease, among which, the use of cultivars with genetic resistance is the most effective and economical. The aim of this study was to in.. Read More»
- Genet. Mol. Res. 15(4):
- gmr15049399
- DOI:
- 10.4238/gmr15049399
Gene expression in the lignin biosynthesis pathway during soybean seed development
Authors: A. Baldoni, E.V.R. Von Pinho, J.S. Fernandes, V.M. Abreu and M.L.M. Carvalho
The study of gene expression in plants is fundamental, and understanding the molecular mechanisms involved in important biological processes, such as biochemical pathways or signaling that are used or manipulated in improvement programs, are key for the production of high-quality soybean seeds. Reports related to gene expression of lignin in seeds are sca.. Read More»
- Genet. Mol. Res. 12(3):
- 2013.February.28.2
- DOI:
- 10.4238/2013.February.28.2
Association between TXNRD1 polymorphisms and anti-tuberculosis drug-induced hepatotoxicity in a prospective study
Authors: G.Y. Ji, Y. Wang, S.Q. Wu, Q.Q. Liu, J.C. Wu, M.M. Zhang, A.J. Sandford and J.Q. He
Anti-tuberculosis drug-induced hepatotoxicity (ATDH) is a serious adverse reaction to anti-tuberculosis (TB) treatment. Thioredoxin reductase 1 (TXNRD1), encoded by the TXNRD1 gene, is an important enzyme involved in oxidant challenge. TXNRD1 plays a key role in regulating cell growth and transformation, and protects cells aga.. Read More»
- Genet. Mol. Res. 15(3):
- gmr.15038296
- DOI:
- 10.4238/gmr.15038296
Segregation and genetic linkage analyses of river catfish, Mystus nemurus, based on microsatellite markers
Authors: B.P. Hoh, S.S. Siraj, S.G. Tan and K. Yusoff
The river catfish Mystus nemurus is an important fresh water species for aquaculture in Malaysia. We report the first genetic linkage map of M. nemurus based on segregation analysis and a linkage map using newly developed microsatellite markers of M. nemurus. A total of 70 of the newly developed polymorphic DNA microsatellite markers were analyzed on pedi.. Read More»
- Genet. Mol. Res. 12(3):
- 2013.February.28.1
- DOI:
- 10.4238/2013.February.28.1
Effects of ginsenoside Rg1 on the senescence of vascular smooth muscle cells
Authors: S.G. Li, M.Z. Yan, D. Zhang, M. Ye and J.J. Deng
The development of age-related cardiovascular disease is associated with the senescence of vascular cells. This study aimed to investigate the effect of ginsenoside Rg1 on vascular smooth muscle cell (VSMC) senescence. Primary VSMCs were cultured and divided into control, D-galactose (D-gal), Rg1-L, and Rg1-H groups, which wer.. Read More»
- Genet. Mol. Res. 15(3):
- gmr.15038409
- DOI:
- 10.4238/gmr.15038409