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Microbial Genetics   Research Article

Genes involved in glucose repression and oxidative stress response in the fission yeast Schizosaccharomyces pombe

Authors: K.G. Suslu, B. Palabiyik and G. Temizkan

We looked for changes in gene expression and novel genes that could be involved in the interaction between glucose repression and oxidative stress response in the fission yeast, Schizosaccharomyces pombe, using a constitutive invertase mutant, ird11, which is resistant to glucose. BLAST analysis was made of the S. pombe genome.. Read More»

Genet. Mol. Res. 10(4):
2011.November.8.4
DOI:
10.4238/2011.November.8.4
Animal Genetics   Research Article

Associations between polymorphisms of the GFI1B gene and growth traits of indigenous Chinese goats.

Authors: H.F. Cai, Z. Chen and W.X. Luo

This study aimed to investigate polymorphisms of the eighth exon in the GFI1B gene among three indigenous Chinese goat breeds (QianBei Ma goats, GuiZhou white goats, and GuiZhou black goats). Furthermore, association analysis was conducted between these polymorphisms and growth traits. Polymerase chain reaction-single strand conformation polymorphism (PCR.. Read More»

Genet. Mol. Res. 13(1):
2014.February.13.5
DOI:
10.4238/2014.February.13.5
Animal Genetics   Research Article

Detection of polymorphisms of the mtDNA control region of Caretta caretta (Testudines: Cheloniidae) by PCR-SSCP

Authors: E.C. Reis R.M. Albano A.C.V. Bondioli L.S. Soares G. L�´bo-Hajdu

Marine turtles are increasingly being threatened worldwide by anthropogenic activities. Better understanding of their life cycle, behavior and population structure is imperative for the design of adequate conservation strategies. The mtDNA control region is a fast-evolving matrilineal marker that has been employed in the study.. Read More»

Genet. Mol. Res. 8(1):
vol8-1gmr570
DOI:
10.4238/vol8-1gmr570
Microbial Genetics   Research Article

Chromosome number, microsporogenesis, microgametogenesis, and pollen viability in the Brazilian native grass Mesosetum chaseae (Poaceae)

Authors: L.A.C. Silva M.S. Pagliarini S.A. Santos N. Silva V.F. Souza

The genus Mesosetum is a primarily South American genus with 42 species. Mesosetum chaseae, regionally known as âÂ?Â?grama-do-cerradoâÂ?Â?, is abundant in the Pantanal Matogrossense (Brazil); it is a valuable resource for livestock and for environmental conservation. We collected specimens from the Nhecolandia sub-region of the Brazilian Pantanal, located .. Read More»

Genet. Mol. Res. 11(4):
2012.September.12.1
DOI:
10.4238/2012.September.12.1
Human Genetics   Research Article

Comparative phylogenetic study of Stichotrichia (Alveolata: Ciliophora: Spirotrichea) based on 18S-rDNA sequences

Authors: T.S. Paiva B.N. Borges M.L. Harada I.D. Silva-Neto

Since molecular phylogenies of stichotrich ciliates started to be published, some remarkable contradictions to morphology- based classifications have been reported, such as the Convergent Evolution of Urostylids and Uroleptids (CEUU) hyphothesis, the Halteria paradox, the polyphyly of Oxytricha and of Stichotrichia. We hypothe.. Read More»

Genet. Mol. Res. 8(1):
vol8-1gmr529
DOI:
10.4238/vol8-1gmr529
Human Genetics   Research Article

Isolation and characterization of HC1: a novel human DNA repair gene

Authors: D.O. Lopes F.C. Falconi A.M. Goes Y. Canitrot J.S. Hoffmann C. Cazaux G.R. Franco A.M. Macedo S.D.J. Pena C.R. Machado

Nucleotide excision repair (NER) acts on a broad spectrum of large lesions, while base excision repair removes individual modified bases. Although both processes have been well studied in human cells, novel genes involved in these DNA repair pathways have been described. Using a heterologous complementation approach, we identi.. Read More»

Genet. Mol. Res. 8(1):
vol8-1gmr554
DOI:
10.4238/vol8-1gmr554
Microbial Genetics   Research Article

Genetic diversity of endangered Polyporus umbellatus from China assessed using a sequence-related amplified polymorphism technique

Authors: Y. Zhang Y. Kang Y. Qin Z. Zhou M. Lei H. Guo

Polyporus umbellatus (Pers.) Fries is an endangered medicinal fungus in China with in vivo anticancer activity, but its genetic information is lacking. Eight natural P. umbellatus strains collected from 7 provinces in China were subjected to sequence-related amplified polymorphism markers to estimate the level and pattern of genetic diversity. Forty-nine .. Read More»

Genet. Mol. Res. 11(4):
2012.December.3.1
DOI:
10.4238/2012.December.3.1
Animal Genetics   Research Article

Transcriptional co-activator PGC-1�± gene is associated with chicken skeletal muscle fiber types

Authors: J.T. Shu, W.J. Xu, M. Zhang, W.T. Song, Y.J. Shan, C. Song, W.Q. Zhu, X.Y. Zhang and H.F. Li

The peroxisome proliferators-activated receptor-γ coactivator-1α (PGC-1α) is a candidate gene for meat quality traits because of its prominent role in muscle fiber type switching and determination. We investigated the effects of the PGC-1α gene on chicken skeletal muscle fiber type switching and on othe.. Read More»

Genet. Mol. Res. 13(1):
2014.February.14.19
DOI:
10.4238/2014.February.14.19
Plant Genetics   Research Article

Ascorbate peroxidase from Jatropha curcas enhances salt tolerance in transgenic Arabidopsis

Authors: Y. Chen, J. Cai, F.X.Yang, B. Zhou and L.R. Zhou

Ascorbate peroxidase (APX) plays a central role in the ascorbate-glutathione cycle and is a key enzyme in cellular H2 O2 metabolism. It includes a family of isoenzymes with different characteristics, which are identified in many higher plants. In the present study, we isolated the APX gene from Jatropha curcas L, which is similar with other previously ch.. Read More»

Genet. Mol. Res. 14(2):
2015.May.11.20
DOI:
10.4238/2015.May.11.20
Medical Genetics   Research Article

Han Chinese patients with dopa-responsive dystonia exhibit a low frequency of exonic deletion in the GCH1 gene

Authors: W.T. Shi, C.Y. Cai, M.S. Li, C. Ling and W.D. Li

We identified three novel mutations of the GTP cyclohydrolase 1 (GCH1) gene in patients with familial dopa-responsive dystonia (DRD), but were unable to identify meaningful sporadic mutations in patients with no obvious family DRD background. To investigate whether GCH1 regional deletions account for the etiology of DRD, we screened for heterozygous exoni.. Read More»

Genet. Mol. Res. 14(3):
http://dx.doi.org/2015.September.22.12
DOI:
http://dx.doi.org/10.4238/2015.September.22.12