Rna
Comparative transcriptome analysis of self-incompatible flower stigmas and self-compatible bud stigmas following self-pollination in broccoliComparative transcriptome analysis of self-incompatible flower stigmas and self-compatible bud stigmas followingself-pollination in broccoli
Authors: H.F. Yu, J.S. Wang, X.G. Sheng, Z.Q. Zhao, Z.R. Qi H.H. Gu
DH07 is a DH line of Class I S-haplotype in broccoli (Brassica oleracea var. italica), in which stigmas of flowers show self-incompatibility (SI) and stigmas of buds show self-compatibility (SC). The molecular mechanisms that lead to stigmas at different developmental stages having different responses to self-pollination are y.. Read More»
- Genet. Mol. Res. 16(1):
- gmr16019018
- DOI:
- 10.4238/gmr16019018
Predicted philogeny, secondary conformational structure, and epitope antigenicity of immunological sequences in poultry
Authors: L.J. Lara, A.P. Peconick, ��.J. Fassani, A.M.P. J�ºnior, P.R.B. Chalfun, D.L. Raymundo, T.A. Bar�§ante and J.M. de P. Bar�§ante
Poultry production is faced with different types of stresses that are responsible for issues of animal welfare as well as for economic losses. Moreover, the immunity decreases when animals are stressed. In silico analyses are important in reducing the cost and in increasing the accuracy of scientific results. A bioinformatics .. Read More»
- Genet. Mol. Res. 16(2):
- gmr16029423
- DOI:
- 10.4238/gmr16029423
Biological analysis of chronic lymphocytic leukemia: integration of mRNA and microRNA expression profiles
Authors: L. Dong1, K.H. Bi1, N. Huang1 and C.Y. Chen2
Chronic lymphocytic leukemia (CLL) is a disease that involves progressive accumulation of nonfunctioning lymphocytes and has a low cure rate. There is an urgent requirement to determine the molecular mechanism underlying this disease in order to improve the early diagnosis and treatment of CLL. In this study, genes differentially expressed between CLL sam.. Read More»
- Genet. Mol. Res. 15(1):
- gmr.15017170
- DOI:
- 10.4238/gmr.15017170
MicroRNA-215 functions as a tumor suppressor and directly targets ZEB2 in human pancreatic cancer
Authors: Q.W. Li,T. Zhou, F. Wang,M. Jiang, C.B. Liu, K.R. Zhang, Q. Zhou, Z. Tian, K.W. Hu
It has been shown that microRNA-215 (miR-215) is dysregulated in several human malignancies, and this correlates with tumor progression. However, its expression and function in pancreatic cancer is still unclear. The aim of this study was to explore the effects of miR-215 on pancreatic cancer formation and progression. Using q.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.8.2
- DOI:
- 10.4238/2015.December.8.2
Effects of VEGF/VEGFR/K-ras signaling pathways on miRNA21 levels in hepatocellular carcinoma tissues in rats
Authors: J.Z. Gao, Y.L. Wang, J. Li and L.X. Wei
The aim of this study was to investigate the effects of the vascular endothelial growth factor (VEGF)/VEGF receptor (VEGFR)/K-ras signaling pathways on miRNA21 levels in hepatocellular carcinoma tissues in rats. Eighteen male Sprague-Dawley rats were randomly divided into normal control, model, and VEGF blocking agent groups (N = 6/group). The expression of .. Read More»
- Genet. Mol. Res. 14(1):
- 2015.January.30.10
- DOI:
- 10.4238/2015.January.30.10
Analysis of Antarctic proteobacteria by PCR fingerprinting and screening for antimicrobial secondary metabolites
Authors: L.-H. Lee, Y.-K. Cheah, A.M. Nurul Syakima, M.S. Shiran, Y.-L. Tang, H.-P. Lin and K. Hong
Fifty-seven proteobacterium species were successfully isolated from soils of Barrientos Island of the Antarctic using 11 different isolation media. Analysis of 16S rDNA sequencing of these isolates showed that they belonged to eight different genera, namely Bradyrhizobium, Sphingomonas, Methylobacterium, Caulobacter, Paracoccu.. Read More»
- Genet. Mol. Res. 11(2):
- 2012.June.15.12
- DOI:
- 10.4238/2012.June.15.12
Establishment of a prediction model for the miRNA-based heading date characteristics of rice in the booting stage
Authors: Y.C. Chen, W.S. Lin, R.K. Chen, Y.Y. Chao, S.W. Chin, F.C. Chen and C.Y. Lee
Rice (Oryza sativa L.) is one of the most important food crops in the world. In Taiwan, due to the warm climate, there are two harvests annually. However, the yield and quality of rice can vary between each crop season in any given year. Previous reports have shown that microRNAs (miRNAs) play a crucial role in many developmental and physiological process.. Read More»
- Genet. Mol. Res. 14(2):
- 2015.April.30.11
- DOI:
- 10.4238/2015.April.30.11
Differential microRNA expression in signet-ring cell carcinoma compared with tubular adenocarcinoma of human gastric cancer
Authors: F.Q. Li, B. Xu, Y.J. Wu Z.L. Yang and J.J. Qian
Gastric cancer is a disease with a heterogeneous pathology; its pathological mechanisms remain unclear because there is a poor understanding of its etiology. In this study, we identified differentially expressed microRNAs (miRNAs) among various gastric cancer subtypes. miRNA microarray analysis and bioinformatic analysis were used to compare miRNA expression.. Read More»
- Genet. Mol. Res. 14(1):
- 2015.January.30.17
- DOI:
- 10.4238/2015.January.30.17
Expression of splice variants of cancer-testis genes ODF3 and ODF4 in the testis of a prostate cancer patient
Authors: S. Ghafouri-Fard M.H. Modarressi
The outer dense fiber (ODF) genes encode proteins that co-assemble along the axoneme of the sperm tail. Recently, it was demonstrated that some ODF genes are aberrantly expressed in tumors, including prostate adenocarcinoma, basal cell carcinoma, and chronic myeloid lymphoma. We cloned ODF3 and ODF4 cDNA from the testis of a patient suffering from prostat.. Read More»
- Genet. Mol. Res. 11(4):
- 2012.October.4.11
- DOI:
- 10.4238/2012.October.4.11
Association of miR-149C>T and miR-499A>G polymorphisms with the risk of hepatocellular carcinoma in the Chinese population
Authors: X.H. Wang, F.R. Wang, Y.F. Tang, H.Z. Zou and Y.Q. Zhao
We investigate the potential association of miR-149C>T and miR-499A>G polymorphisms and the risk of hepatocellular carcinoma (HCC). A matched case-control study of 152 cases and 304 controls were conducted. The miR-149C>T and miR-499A>G genotypes were analyzed using duplex polymerase chain reaction with restricted .. Read More»
- Genet. Mol. Res. 13(3):
- 2014.July.4.20
- DOI:
- 10.4238/2014.July.4.20