Polymorphism
Isolation and characterization of eight polymorphic microsatellite loci for the coconut pest, Brontispa longissima (Coleoptera: Hispidae)
Authors: C.L. Ma, H.L. Wu, H.Y. Hu, X. Wu, G.C. Ma, Y.G. Fu and Z.Q. Peng
Brontispa longissima is one of the most serious insect pests of coconut in Southeast Asia; it was first discovered on Hainan Island in June 2002. Despite the economic risk associated with this pest, genetic aspects of the invasion process have remained relatively unexplored. Using microsatellite markers, we investigated the po.. Read More»
- Genet. Mol. Res. 10(1):
- vol10-1gmr1008
- DOI:
- 10.4238/vol10-1gmr1008
A case-control study of CYP2E1 (PstI) and CYP1A1 (MspI) polymorphisms in colorectal cancer
Authors: M.A. Proen�§a, G.M.M. Fernandes, A. Russo, R.B. Lelis, J.G. Netinho, G.S. Cunrath, A.E. Silva, E.M. Goloni-Bertollo and E.C. Pavarino
Polymorphisms in genes encoding P450 cytochrome enzymes may increase the risk of sporadic colorectal cancer (SCRC). Here we investigated the association between SCRC and CYP2E1 (PstI) and CYP1A1 (MspI) polymorphisms in a case-control study. Moreover, we sought to determine any possible associations between this disease and the sociodemographic factors. We.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.22.10
- DOI:
- 10.4238/2015.December.22.10
Pooled analysis of association between a genetic variant in the 3'-untranslated region of Toll-like receptor 4 and cancer risk
Authors: X. Wang, Z. Xu and C.H. Miao
Many epidemiological studies have shown the association between certain genetic variations in the Toll-like receptor 4 (TLR4) gene (for example, rs4986790 and rs4986791) and cancer risk. However, the results from investigations into the association between rs11536889, a genetic variant in the 3'-untranslated region of TLR4, and cancer risk lack consensus... Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.22.9
- DOI:
- 10.4238/2015.December.22.9
Lack of association of single nucleotide polymorphisms of the bovine Flt-1 gene with growth traits in Chinese cattle breeds
Authors: Y.H. Pang, C.Z. Lei, C.L. Zhang, X.Y. Lan, S. Shao, X.M. Gao, J.Q. Wang and H. Chen
We analyzed 20 exons, with their intron-exon boundaries, of the bovine Flt-1 gene, using a strategy combining PCR amplification and single-strand conformational polymorphism analysis (PCR-SSCP), followed by nucleotide sequence analysis, in 675 cattle. We then looked for associations between polymorphisms and growth traits. Twe.. Read More»
- Genet. Mol. Res. 10(1):
- vol10-1gmr1041
- DOI:
- 10.4238/vol10-1gmr1041
Acetaldehyde dehydrogenase 2 SNP rs671 and susceptibility to essential hypertension in Mongolians: a case control study
Authors: T. Hasi, L. Hao, L. Yang and X.L. Su
Mongolians are known as heavy drinkers, and they have a high incidence of essential hypertension, which may be an associated pathology. We examined a possible association of essential hypertension and polymorphism of the aldehyde dehydrogenase 2 (ALDH2) gene in Mongolians from Inner Mongolia. Single nucleotide polymorphism rs6.. Read More»
- Genet. Mol. Res. 10(1):
- vol10-1gmr1056
- DOI:
- 10.4238/vol10-1gmr1056
Assessment of CASP gene polymorphisms in periodontal disease
Authors: S.W. Kang, S.K. Kim, J.H. Chung and J.Y. Ban
Caspases (CASP) are intracellular proteases that play roles as mediators of apoptosis. Activation of caspase 3 is enhanced in chronic periodontitis. Thus, we hypothesized that single nucleotide polymorphisms (SNPs) of CASP genes might be associated with this condition in the Korean population. To investigate whether such polymorphisms might be involved in.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.22.33
- DOI:
- 10.4238/2015.December.22.33
RsaI polymorphism of the ER�² gene in women with endometriosis
Authors: R.C.P.C. Silva, I.R. Costa, B.M Bordin, C.T.X. Silva, S.R. Souza, C.L.R. J�ºnior, A.B. Frare and K.K.V.O. Moura
We examined the frequency of RsaI polymorphism of the ERβ gene in 54 patients diagnosed with endometriosis and 46 controls. Peripheral blood was collected from women undergoing laparoscopy with a confirmed diagnosis of endometriosis. Polymorphisms of the ERβ gene and p53 were assessed by PCR and analyzed on 2% agaros.. Read More»
- Genet. Mol. Res. 10(1):
- vol10-1gmr940
- DOI:
- 10.4238/vol10-1gmr940
Association between the XRCC1 Arg399Gln polymorphism and risk of cervical carcinoma: a meta-analysis
Authors: D.Y. Liu, H.C. Liang and X.M. Xiao
Numerous studies have evaluated the association between Arg399Gln polymorphism of DNA repair gene XRCC1 and cervical carcinoma risk. However, the specific association is still controversial. To assess the relationship between XRCC1 Arg399Gln polymorphism and cervical carcinoma, we conducted a comprehensive meta-analysis of 10 case-control studies with 205.. Read More»
- Genet. Mol. Res. 14(3):
- 2015.August.19.15
- DOI:
- 10.4238/2015.August.19.15
Vascular endothelial growth factor gene is associated with hypertensive cerebellar hemorrhage and rehabilitative treatment
Authors: Q.S. He, L.F. Yang, W.B. Wang, B. Yuan, L.Y. Zhang and X.J. Guo
Early rehabilitative therapy is important for patients with hypertensive cerebral hemorrhage to improve long-term function of the extremities. Vascular endothelial growth factor (VEGF) is closely associated with the pathogenesis of hypertension. To identify the markers contributing to the genetic susceptibility to hypertensive cerebellar hemorrhage (HCH) .. Read More»
- Genet. Mol. Res. 14(3):
- 2015.August.19.18
- DOI:
- 10.4238/2015.August.19.18
De novo assembly, functional annotation, and marker development of Asian pear (Pyrus pyrifolia) fruit transcriptome through massively parallel sequencing
Authors: J.F. Li, Z. Gao, Y.S. Lou, M. Luo, S.R. Song, W.P. Xu, S.P. Wang and C.X. Zhang
This study investigated the Asian pear transcriptome using the RNA-Seq normalized fruit cDNA library to create a transcriptomic resource for unigene and marker discovery. Following the removal of lowquality reads, 127,085,054 trimmed reads were assembled de novo to yield 37,649 non-redundant unigenes with an average length of 599 bp. Alternative splicing .. Read More»
- Genet. Mol. Res. 14(4):
- 2015.December.23.22
- DOI:
- 10.4238/2015.December.23.22