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Plant Genetics   Research Article

Differential expression of dormancy-Associated genes in fastigiata and hypogaea peanut

Authors: M.F.C. Silva, C.R.C. Silva, L.M. Lima, JPC Ramos, and R.C. Santos

Seed dormancy is a temporary replacement state observed in some higher plants, which prevents germination under unfavorable conditions. In several species, dormancy process is triggered by hormonal factors, initiated by ABA and precursor enzymes. In this work, we investigated the relationship between dormancy and the expressio.. Read More»

Genet. Mol. Res. 16(4):
gmr16039820
DOI:
10.4238/gmr16039820
Human Genetics   Research Article

Effect of chromosome constitution variations on the expression of Turner phenotype

Authors: A.V.S. Bispo, L.O. dos Santos, P. Bur�©gio-Frota, M.B. Galdino,A.R. Duarte, G.F. Leal, J. Ara�ºjo, B. Gomes, E.M. Soares-Ventura, M.T.C. Muniz and N. Santos

Turner syndrome (TS) is a chronic disease related to haploinsufficiency of genes that are normally expressed in both X chromosomes in patients with female phenotype that is associated with a wide range of somatic malformations. We made detailed cytogenetic and clinical analysis of 65 patients with TS from the region of Recife, Brazil, to determine the eff.. Read More»

Genet. Mol. Res. 12(4):
2013.March.13.13
DOI:
10.4238/2013.March.13.13
Plant Genetics   Research Article

Identification of quantitative trait loci for blast resistance in BC2F3 and BC2F5 advanced backcross families of rice

Authors: H.A. Rahim M.A.R. Bhuiyan L.S. Lim K.K. Sabu A. Saad M. Azhar R. Wickneswari

Advanced backcross families derived from Oryza sativa cv MR219/O. rufipogon IRGC105491 were utilized for identification of quantitative trait loci (QTL) for blast resistance using simple sequence repeat markers. Two hundred and sixty-one BC2F3 families were used to construct a linkage map, using 87 markers, which covered 2375.2 cM of 12 rice chromosomes, wit.. Read More»

Genet. Mol. Res. 11(3):
2012.September.12.11
DOI:
10.4238/2012.September.12.11
Animal Genetics   Research Article

Identification of introgressed alien chromosome segments associated with grain quality in Oryza rufipogon x MR219 advanced breeding lines using SSR markers

Authors: P. Fasahat K. Muhammad A. Abdullah R. Wickneswari

A limited backcross procedure was utilized to introgress genes associated with grain quality traits from Oryza rufipogon (Accession No. IRGC 105491), a wild rice from Malaysia, to the cultivated rice O. sativa cv. MR219, a popular high yielding Malaysian rice cultivar. A set of 10 BC2F7 progenies were selected based on the field performance and phenotypic.. Read More»

Genet. Mol. Res. 11(3):
2012.September.26.10
DOI:
10.4238/2012.September.26.10
Animal Genetics   Research Article

Transcriptional activity of an ovarian-specific promoter from rat in dairy goat granulosa cells

Authors: H.-Y. Liu M.-M. Yang Y.-H. Cui T. Ma X.-Q. Liu L. Bai W.-P. Xiao H.-B. Zhao J.-Y. Peng X.-B. Hu B.-Y. Cao

Ovarian-specific promoter 1 (OSP-1) is a retrovirus-like element isolated from the complementary DNA library of rat that has been thought to be specifically expressed in ovary. To exploit this promoter in dairy goat ovary granulosa cells (GCs), OSP-1 from rat was used to construct the reporter vector pOSP-1-EGFP, in which egfp coding for enhanced green fl.. Read More»

Genet. Mol. Res. 12(1):
2013.January.24.4
DOI:
10.4238/2013.January.24.4
Animal Genetics   Research Article

Application of 64-slice spiral computed tomography angiography in extremity vascular injuries

Authors: Y.B. Xia, G.M. Pan, C.J. Geng, F. Xue and Y.Y. Xie

The objective of the current study was to assess the utility of 64-row helical computed tomography angiography (CTA) in the evaluation of extremity vascular traumas. The extremities from 17 clinical cases of suspected traumatic vascular damage were evaluated using 64-row helical CTA. To evaluate extremity vascular traumas using CTA, volume rendering, mult.. Read More»

Genet. Mol. Res. 14(1):
2015.January.15.20
DOI:
10.4238/2015.January.15.20
Human Genetics   Research Article

Role of GSTM1, GSTT1, and GSTP1 IIe105Val gene polymorphisms in the response to chemotherapy and overall survival of advanced non-small cell lung cancer

Authors: W. Jia, J.Y. Sun, K.Y. Jia and X.C. Liu

We evaluated the association between GSTM1, GSTT1, and GSTP1 IIe105Val gene polymorphisms and treatment outcomes of advanced non-small cell lung carcinoma. Between January 2010 and December 2012, a total of 244 patients with non-small cell lung carcinoma were recruited from Yiwu Central Hospital. The GSTM1, GSTT1, and GSTP1 IIe105Val gene polymorphisms we.. Read More»

Genet. Mol. Res. 15(3):
gmr.15037668
DOI:
10.4238/gmr.15037668
Human Genetics   Research Article

Hypertension-mediated enhancement of JNK activation in association with endoplasmic reticulum stress in rat model hippocampus with cerebral ischemia-reperfusion

Authors: Y.N. Zhao, J.M. Li, C.X. Chen, P. Zhang and S.X. Li

Acute brain ischemia can induce the activation of c-Jun N-terminal kinases (JNKs). Hypertension is a critical etiology for brain ischemia. We identified the effects of hypertension on the activation of JNK as well as its impact on SP600125, a JNK inhibitor, during endoplasmic reticulum stress (ERS) in the hippocampus using a rat model. Transient whole-brain .. Read More»

Genet. Mol. Res. 14(3):
http://dx.doi.org/2015.September.21.10
DOI:
http://dx.doi.org/10.4238/2015.September.21.10
Human Genetics   Research Article

Effect of RAGE polymorphisms on susceptibility to and severity of osteoarthritis in a Han Chinese population: a case-control study

Authors: H.Y. Yang, S.Y. Chuang, W.H. Fang, G.S. Huang, C.C. Wang, Y.Y. Huang, M.Y. Chu, C. Lin, W. Su, C.Y. Chen, Y.T. Yang and S.L. Su

Recent studies have revealed that the inflammatory process plays a role in the pathogenesis of osteoarthritis (OA). The S100 family and receptor for advanced glycation end products (RAGE)participate in regulating inflammation, even in the production of matrix metalloproteinases (MMPs). MMP-1 degrades cartilage, which may result in OA development. Moreover.. Read More»

Genet. Mol. Res. 14(3):
http://dx.doi.org/2015.September.25.3
DOI:
http://dx.doi.org/10.4238/2015.September.25.3
Medical Genetics   Case Reports

Local skin flap with vacuum-seal drainage to facilitate healing of ACS

Authors: R.B. Luo, Y.A. Xu, H.M. Zhong and Y.F. Zhang

The purpose of this study was to analyze the therapy of a severe abdominal compartment syndrome (ACS) to elucidate the use of an abdominal advanced flap with other supportive measures for restoration of large defects of the abdominal wall. A patient presented with a large defect of the abdominal wall caused by ACS, which had resulted from multiple injurie.. Read More»

Genet. Mol. Res. 14(2):
http://dx.doi.org/2015.April.10.3
DOI:
http://dx.doi.org/10.4238/2015.April.10.3