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Medical Genetics   Research Article

Cloning and functional identification of a novel BCA3 splice

Authors: Y. Zhang, M.Y. Hu, C.X. Qiao, J.N. Feng, Z. Lin, B.F. Shen2, Y.F. Ma, Y. Li, Y.L. Li and M.

The human breast cancer-associated gene (BCA3) was first discovered in breast and prostate cancer cells lines. In vivo studies have shown that BCA3 is mainly expressed in breast tumor cells and not in normal breast and prostate tissues. To date, 3 splice variants of BCA3 have been reported: a double-absent variant lacking exon 3 and exon 5 (BCA3-1), an ex.. Read More»

Genet. Mol. Res. 13(4):
Bioinformatics   Research Article

Characterization of abnormal epithelium after laser-assisted subepithelial keratectomy using in vivo confocal microscopy

Authors: J. Zuo, C.W. Zhang, X. Zhou, W. Wei and Y.L. Wang

This study compared the abnormal corneal epithelium after laser-assisted subepithelial keratectomy (LASEK) with dystrophic cornea using in vivo using confocal microscopy (IVCM) and examined the effects of the abnormal epithelium on postoperative recovery of uncorrected distance visual acuity (UDVA) and sub-basal nerve plexus regeneration. The UDVA and wou.. Read More»

Genet. Mol. Res. 14(2):
Plant Genetics   Research Article

The pollen wall and tapetum are altered in the cytoplasmic male sterile line RC7 of Chinese cabbage (Brassica campestris ssp pekinensis)

Authors: H.-F. Zhao W. Huang S.S. Ahmed Z.-H. Gong L.-M. Zhao

Cytoplasmic male sterile line RC7 of Chinese cabbage produces mature anthers without pollen. To understand the mechanisms involved, we examined the ultrastructural changes during development of the microspores. Development of microspores was not affected at the early tetrad stage. During the ring-vacuolated period, some large vacuoles appeared in the tape.. Read More»

Genet. Mol. Res. 11(4):
Plant Genetics   Research Article

Activity and expression of polygalacturonase vary at different fruit ripening stages of sweet pepper cultivars

Authors: S.S. Ahmed, Z.-H. Gong, M.A. Khan, Y.-X. Yin, W.-L. Guo and J. Imran

Activity and expression of polygalacturonase (PG), a hydrolytic enzyme involved in ultrastructural changes in the pericarp of sweet pepper (Capsicum annaum), were investigated at different ripening stages of the pepper cultivars Mandi and Talanduo. Molecular cloning of CaPG was carried out by constructing a cDNA library from t.. Read More»

Genet. Mol. Res. 10(4):
Animal Genetics   Research Article

Preponderance of GC-rich sites in silver-stained nucleolus organizing regions of Rita rita (Hamilton) and Mystus gulio (Hamilton) (Bagridae, Pisces), as revealed by chromomycin A3-staining technique and scanning electron microscopic studies

Authors: Das JK and Khuda-Bukhsh AR

The karyotypes of two species of catfish, Rita rita (Hamilton) (2n = 54; 14m + 34sm + 6st; NF = 102) and Mystus gulio (Hamilton) (2n = 58; 30m + 12sm + 2st + 14t, NF = 100) were studied through Giemsa-, silver- and chromomycin A3-staining techniques. The silver-stained karyotypes in both sexes of R. rita and M. gulio revealed .. Read More»

Genet. Mol. Res. 6(2):
Microbial Genetics   Research Article

Bos taurus papillomavirus activity in peripheral blood mononuclear cells: demonstrating a productive infection

Authors: T.C. Melo, R.P. Araldi, N.S.D. Pessoa, P.L. de-Sá-Júnior, R.F. Carvalho, W. Beçak and R.C. Stocco

Bovine papillomavirus (BPV) is an oncogenic virus with mucous and epithelial tropism. Possible productive virus infection in other tissues, such as blood, has been hypothesized. In order to investigate this possibility, three samples of skin papillomas and blood were collected from bovines with BPV infection and five samples of peripheral blood and one sa.. Read More»

Genet. Mol. Res. 14(4):
Animal Genetics   Research Article

Macromolecular array patterns of silk gland secretion in social Hymenoptera larvae

Authors: Guilherme Gomes, Elaine C.M. Silva-Zacarin, Fernando J. Zara, Regina L.M. Silva de Moraes and Flávio H. Caetano

The cocoon, produced by most holometabolous insects, is built with silk that is usually produced by the larval salivary gland. Although this silk has been widely studied in the Lepidoptera, its composition and macromolecular arrangement remains unknown in the Hymenoptera. The macromolecular array patterns of the silk in the la.. Read More»

Genet. Mol. Res. 3(3):


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