Gene
Identification, Characterization, and Phylogenetic analysis of Pigeon pea (Cajanus cajan L. Mill sp.) Resistance Gene Analogs using PCR cloning and in silico methods
Authors: Ikechukwu O. Agbagwa, Prakash G. Patil, Alok Das, Khela R. Soren, Indra P. Singh, Sushil K. Chaturvedi, Nagaswamy Nadarajan
Pigeon Pea (Cajanus cajan), an important grain legume, is susceptible to Fusarium wilt (FW), sterility mosaic disease (SMD), and Phytophthora blight. Identification of resistance gene analogs (RGAs) is important for development of resistant varieties. In this study, degenerate primers targeting nucleotide binding sites (NBS) o.. Read More»
- Genet. Mol. Res. 17(1):
- gmr16039896
- DOI:
- 10.4238/gmr16039896
Screening and identification of candidate genes essential for cervical lymph node metastasis in nasopharyngeal carcinoma with microarrays
Authors: Ming Fu, Yudong Ye, Chi Zhang, Zhuo Chen, Zhenchao Zhu, Yang Peng, Xiangning Zhang, Qianhui Qiu
The aim of the present study is to identify genes that are crucial for the cervical lymph node metastasis, which predicts poor prognosis of nasopharyngeal carcinoma (NPC), endemic in southern China. Microarrays with probes to determine genomic expression profile and promoter methylation status in tumor specimens were used, to .. Read More»
- Genet. Mol. Res. 17(1):
- gmr16039892
- DOI:
- 10.4238/gmr16039892
Genetic Polymorphism in Endometriosis: Trends in Scientific Production
Authors: Maria Gabriela Machado Junqueira, Amanda Fernandes Costa, Felipe de Ara�ºjo Nascimento, K�¡tia Karina Verolli de Oliveira Moura, Fl�¡via Melo Rodrigues
Endometriosis is characterized by the presence of endometrial tissue located outside the uterine cavity. The prevalence is around 6 to 10%. Regarding etiopathogenesis, several theories are accepted, but alterations in the molecular biology of the endometrium seem to be fundamental for the development of endometriosis. Women wi.. Read More»
- Genet. Mol. Res. 17(1):
- gmr16039891
- DOI:
- 10.4238/gmr16039891
Predominance of the A allele but no association of the KCNJ11 rs5219 E23K polymorphism with Type 2 Diabetes in a Nigerian population
Authors: Godwill Azeh Engwa, Friday Nweke Nwalo, Chosen E. Obi, Christie Onyia, Opeolu Oyejide Ojo Wilfred Fon Mbacham, Benjamin Ewa Ubi
Though the rs5219 E23K variant of the KCNJ11 gene is commonly known to be associated with Type 2 diabetes (T2D) in Caucasian and Asian populations, little or none of such findings have been revealed in Nigeria. Hence, this study was aimed to assess the relationship between E23K polymorphic variant of the KCNJ11 gene and T2D in.. Read More»
- Genet. Mol. Res. 17(1):
- gmr16039889
- DOI:
- 10.4238/gmr16039889
The Disruption of Klf6-Related Super-Enhancer Induces Growth Inhibition and Apoptosis in Human HepG2 Cells
Authors: KumChol Ri, KumChol Kim, SunHyok Kong, JuHua Ri
Klf6 is a member of the Krüppel-like factor family, which is a group of zinc finger transcription factors involved in differentiation and development. In general, Klf6 gene plays an important role in growth-related signal transduction pathways, cell proliferation, apoptosis, and angiogenesis. Recently, the Klf6 gene is co.. Read More»
- Genet. Mol. Res. 17(1):
- gmr16039888
- DOI:
- 10.4238/gmr16039888
Estimate of natural cross-pollination rate of Capsicum annuum using a codominant molecular marker associated with fruit pungency
Authors: EV Justino, MEN Fonseca, ME Ferreira, LS Boiteux, PP Silva, WM Nascimento
The production of seeds with high genetic quality requires accurate estimates of the natural cross-pollination rate in cultivated Capsicum species. This is important in order to establish the most suitable isolation distance among fields of distinct genotypes, to minimize the risk of genetic contamination and to ensure that th.. Read More»
- Genet. Mol. Res. 17(1):
- gmr16039887
- DOI:
- 10.4238/gmr16039887
Agronomic performance of plantain genotypes and genetic variability using Ward-MLM algorithm
Authors: Z. S. Gon�§alves, D. R. S. da Inven�§�£o, C. A. da S. Ledo, C. F. Ferreira, E. P. Amorim
Plantains in Brazil are produced from the `Terra Maranhão’, ‘Terrinha’ and ‘D´Angola’ cultivars, which are all susceptible to black Sigatoka, weevils and nematodes. Therefore, the development of resistant plantain cultivars with agronomic characteristics aligned with market demands i.. Read More»
- Genet. Mol. Res. 17(1):
- gmr16039882
- DOI:
- 10.4238/gmr16039882
Retrospective Investigation of Interleukin 1 and 6 Gene Polymorphism among Elderly Patients with Sarcopenia in the Turkish Population
Authors: Pinar Tosun Tasar
Introduction: Sarcopenia, one of the geriatric syndromes, is defined as generalized and progressive reduction in skeletal muscle mass accompanied by loss of muscle strength and/or function. There is a paucity of research in the Turkish population about the effects of interleukin 1 (IL-1) and IL-6 gene polymorphism on sarcopeni.. Read More»
- Genet. Mol. Res. 17(1):
- gmr16039881
- DOI:
- 10.4238/gmr16039881
New insights into the genetic diversity and species identification of the native apricots in Southern Xinjiang of China
Authors: Ling Guo, Hui Li, Zheng-rong Luoa
Apricot is a staple stone fruit crop cultivated in Southern Xinjiang of China. This crop is important for the rural communities, as they generate significant employment and income. Here, seventy-eight apricot genotypes, including seventy-six common apricots (Prunus armeniaca L.) and two purple apricots (Prunus dasycarpa Ehrh.).. Read More»
- Genet. Mol. Res. 17(1):
- gmr16039874
- DOI:
- 10.4238/gmr16039874
Hierarchical outcrossing among and within fruits in Bertholletia excelsa Bonpl. (Lecythidaceae) open-pollinated seeds
Authors: L.D. Giustina, A.B. Baldoni, H. Tonini, V.C.R. Azevedo, L.G. Neves, F.D. Tardin, A.M. Sebbenn
Knowing the mating patterns is important to determine the number of trees necessary for seed collection for conservation ex situ, tree breeding and environmental reforestation purposes. We investigated B. excelsa individuals and fruits, to check mating system index variations in a population by using open-pollinated seeds whic.. Read More»
- Genet. Mol. Res. 17(1):
- gmr16039872
- DOI:
- 10.4238/gmr16039872