Gene
RANTES gene polymorphisms (-403G>A and -28C>G) associated with hepatitis B virus infection in a Saudi population
Authors: A. Al-Qahtani, S. Alarifi, M. Al-Okail, Z. Hussain4, A. Abdo, F. Sanai, M. Al-Anazi, N. Khalaf, H. Al-Humaidan, M. Al-Ahdal and F.N. Almajhdi
Besides the host immune response, genetic and environmental factors play crucial roles in the manifestation of hepatitis B virus (HBV) infection. “Regulated on activation normal T-cell expressed and secreted” factor (RANTES) plays a vital role in CD4+, CD8+ T-lymphocyte and dendritic cell activation and proliferati.. Read More»
- Genet. Mol. Res. 11(2):
- 2012.April.10.1
- DOI:
- 10.4238/2012.April.10.1
Boric acid increases the expression levels of human anion exchanger genes SLC4A2 and SLC4A3
Authors: F. Akbas and Z. Aydin
Boron is an important micronutrient in plants and animals. The role of boron in living systems includes coordinated regulation of gene expression, growth and proliferation of higher plants and animals. There are several well-defined genes associated with boron transportation and tolerance in plants and these genes show close h.. Read More»
- Genet. Mol. Res. 11(2):
- 2012.April.3.6
- DOI:
- 10.4238/2012.April.3.6
Polymorphisms of DNA repair-related genes with susceptibility and prognosis of prostate cancer
Authors: X.J. Zhang, P. Liu and F. Zhu
We aimed to investigate the association between genetic variants of the DNA repair genes XPG, CSB, XPC, CCNH, and MMS19L in the nucleotide excision repair (NER) pathway and risk of prostate cancer in a population in China. This study included 229 patients with newly diagnosed and histopathologically confirmed primary prostate .. Read More»
- Genet. Mol. Res. 13(2):
- 2014.January.24.20
- DOI:
- 10.4238/2014.January.24.20
Role of survivin in the pathogenesis of papillary thyroid carcinoma
Authors: J.Y. Li, J. Shi, J.F. Sang, Y.Z. Yao, X.C. Wang and L. Su
The purpose of this study was to assess the correlation between the survivin gene and the occurrence and pathogenesis of papillary thyroid carcinoma (PTC). Sixty patients with PTC and no preoperative chemotherapy were recruited for the study and 30 thyrophyma patients receiving operative treatment in Drum Tower Hospital (Nanji.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.November.24.19
- DOI:
- 10.4238/2015.November.24.19
Novel polymorphic microsatellite markers for Bellamya and their application in population genetics of three species
Authors: Q.H. Gu, Q.Q. Cheng, X.J. Li and C.J. Zhou
Bellamya is a widely distributed freshwater snail genus in China; however, its genetic diversity is completely unknown. Sixty-five novel microsatellite loci were isolated and characterized from a microsatellite-enriched library of Bellamya aeruginosa genomic DNA. Most of the 65 loci were successfully amplified. We fou.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.November.25.8
- DOI:
- 10.4238/2015.November.25.8
Expression of CD44 in sheep oocytes and preimplantation embryos
Authors: J.V. Luz, A.S. Alc�¢ntara-Neto, R.I.T.P. Batista, J.M.G. Souza, D.I.A. Teixeira, L.M. Melo and V.J.F. Freitas
The CD44 family belongs to a larger group of hyaluronic acid-binding proteins and plays important roles in oocyte maturation, fertilization and preimplantational embryo development. We analyzed the CD44 receptor in sheep oocytes and embryos. Immature oocytes (N = 66) were obtained from a local abattoir; mature oocytes (N = 35).. Read More»
- Genet. Mol. Res. 11(2):
- 2012.April.3.2
- DOI:
- 10.4238/2012.April.3.2
Molecular cloning and expression of the male sterility-related CtYABBY1 gene in flowering Chinese cabbage (Brassica campestris L. ssp chinensis var. parachinensis)
Authors: X.L. Zhang and L.G. Zhang
Expression of the YABBY gene family in the abaxial surface of lateral plant organs determines abaxial destiny of cells, enhances growth and expansion of lateral organs, and plays an important role in polar establishment of lateral organs. However, the YABBY gene has not been studied in male sterility and fertility restoration... Read More»
- Genet. Mol. Res. 13(2):
- http://dx.doi.org/2014.June.10.1
- DOI:
- http://dx.doi.org/10.4238/2014.June.10.1
Structural and phylogenetic analysis of Pto-type disease resistance gene candidates in Hevea brasiliensis
Authors: W. Zhai, Y. Zhao, L.X. Zhang and X.J. Li
The tomato Pto gene encodes a serine/threonine kinase (STK) whose molecular characterization has provided valuable insights into the disease resistance mechanism of tomato. Therefore, Pto is considered as a promising candidate for engineering broad-spectrum pathogen resistance in this crop. In this study, a pair of degenerate .. Read More»
- Genet. Mol. Res. 13(2):
- http://dx.doi.org/2014.June.10.2
- DOI:
- http://dx.doi.org/10.4238/2014.June.10.2
Biolistic transformation of wheat using the HMW-GS 1Dx5 gene without selectable markers
Authors: J.B. Qin, Y. Wang and C.Q. Zhu
Genetic manipulation using linear DNA was applied to the common wheat variety Xindong No. 26 via particle bombardment with the aim to improve bread-making quality of flour. Initially, 2 biolistic parameters, helium pressure and target distance, were optimized using plasmid pAHC25. We transformed wheat immature embryo scutella .. Read More»
- Genet. Mol. Res. 13(2):
Association between methylene tetrahydrofolate reductase and glutathione S-transferase M1 gene polymorphisms and chronic myeloid leukemia in a Brazilian population
Authors: G.S. Lordelo, A.L. Miranda-Vilela, A.K. Akimoto, P.C.Z. Alves, C.O. Hiragi, A. Nonino, M.B. Daldegan, M.N. Klautau-Guimar�£es and C.K. Grisolia
Chronic myeloid leukemia is a hematopoietic stem cell disorder that causes uncontrolled proliferation of white blood cells. Although the clinical and biological aspects are well documented, little is known about individual susceptibility to this disease. We conducted a case-control study analyzing the prevalence of the polymor.. Read More»
- Genet. Mol. Res. 11(2):
- 2012.April.19.6
- DOI:
- 10.4238/2012.April.19.6