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Gene

Plant Genetics   Research Article

Development of primer pairs from diverse chloroplast genomes for use in plant phylogenetic research

Authors: Y.C. Yang, T.L. Kung, C.Y. Hu and S.F. Lin

Variation in the chloroplast DNA sequence is useful for plant phylogenetic studies. However, the number of variable sequences provided by chloroplast DNA for suggested genes or genomic regions in plant phylogenetic analyses is often inadequate. To identify conserved regions that can be used to design primers and amplify variab.. Read More»

Genet. Mol. Res. 14(4):
2015.November.18.51
DOI:
10.4238/2015.November.18.51
Human Genetics   Research Article

Familial balanced translocation leading to an offspring with phenotypic manifestations of 9p syndrome

Authors: L.S. Abreu, M.S. Brassesco, M.L.C. Moreira, J.M. Pina-Neto

We report two similarly affected cousins (children of monozygotic twin sisters) with phenotypic features consistent with 9p deletion syndrome, including dysmorphic craniofacial features (trigonocephaly, midface hypoplasia, upward-slanting palpebral fissures and long philtrum), intellectual disability and disorders of sex devel.. Read More»

Genet. Mol. Res. 13(2):
http://dx.doi.org/2014.June.9.16
DOI:
http://dx.doi.org/10.4238/2014.June.9.16
Plant Genetics   Research Article

Characterization of nine microsatellite loci for the tree species Parapiptadenia rigida (Fabaceae-Mimosoideae) and their transferability

Authors: B.F. Costa, L.A. Rodrigues, E.A. Ruas, L.B. Souza, C.F. Ruas, B.G. Vieira, A.R.O. Conson and P.M. Ruas

Parapiptadenia rigida, locally known as angico, is a tropical tree common in the semideciduous Brazilian forest. Its wood is naturally resistant to insect attack and is useful for construction. Extracts from the tree have medicinal properties. We characterized nine microsatellite loci for P. rigida. Thirty-five alleles were detected in a sample of 45 indi.. Read More»

Genet. Mol. Res. 11(3):
2012.August.13.7
DOI:
10.4238/2012.August.13.7
Medical Genetics   Research Article

Meta-analysis demonstrates that the NAD(P)H: quinone oxidoreductase 1 (NQO1) gene 609 C>T polymorphism is associated with increased gastric cancer risk in Asians

Authors: Y. Zhang, Z.T. Wang and J. Zhong

The association between the NAD(P)H: quinone oxidoreductase 1 (NQO1) gene C609T polymorphism and gastric cancer has been widely evaluated, yet with conflicting results. Data were available from seven study populations involving 2600 subjects. Overall, comparison of alleles 609T and 609C indicated a significantly increased risk (46%) for gastric cancer (95.. Read More»

Genet. Mol. Res. 11(3):
2012.August.13.6
DOI:
10.4238/2012.August.13.6
Medical Genetics   Research Article

Screening for genes that are differentially-expressed between gastric cancer cells and gastric tumor sphere cells using the gene chip technique

Authors: W.H. Shi, Y.B. Yu, Z.-Y. Li, X.-C. Guo, Z.-L. Wei and Z.-H. Zheng

The purpose of this study was to screen for genes that were differentially expressed between a human gastric carcinoma cell line (HGC-27) and their tumor spheres, using the gene chip technique. The HGC-27 cells and tumor sphere cells were cultured in vitro in a sterile environment. Total RNA was extracted from both sa.. Read More»

Genet. Mol. Res. 14(4):
2015.November.18.54
DOI:
10.4238/2015.November.18.54
Medical Genetics   Review Article

MLH1 and XRCC1 polymorphisms in Mexican patients with colorectal cancer

Authors: R. Mu�±iz-Mendoza, M.L. Ayala-Madrigal, M. Partida-P�©rez, J. Peregrina-Sandoval, E. Leal-Ugarte, N. Mac�­as-G�³mez, V. Peralta-Leal, J.P. Meza-Espinoza, J.M. Moreno-Ortiz, R. Ram�­rez-Ram�­rez, S. Su�¡rez-Villanueva and M. Guti�©rrez-Angulo

DNA repair proteins maintain DNA integrity; polymorphisms in genes coding for these proteins can increase susceptibility to colorectal cancer (CRC) development. We analyzed a possible association of MLH1 -93G>A and 655A>G and XRCC1 Arg194Trp and Arg399Gln polymorphisms with CRC in Mexican patients. Genomic DNA samples were obtained from peripheral b.. Read More»

Genet. Mol. Res. 11(3):
2012.June.27.6
DOI:
10.4238/2012.June.27.6
Plant Genetics   Research Article

Geoffroy�s side-necked turtle [Phrynops geoffroanus (Schweigger, 1812), Testudines: Chelidae] as a model for evolutionary ecotoxicology: relationship between environmental contamination, conditions and genetic variability

Authors: L.P.R. Venancio, D.A.P.C. Zuccari and C.R. Bonini-Domingos

The objective of this study was to evaluate the role of human activity factors, such as environmental contamination and habitat changes, as drivers for changing the physiological, biochemical, and genetic diversity of Geoffroy’s side-necked turtle populations in one of the most impacted watersheds in southeastern Brazil. The impact of chemical and o.. Read More»

Genet. Mol. Res. 12(4):
2013.December.19.4
DOI:
10.4238/2013.December.19.4
Animal Genetics   Research Article

Association between HLA-C*04 and American cutaneous leishmaniasis in endemic region of southern Brazil

Authors: R.C. Ribas-Silva, A.D. Ribas, E.C. Ferreira, T.G.V. Silveira and S.D. Borelli

Leishmaniasis is a parasitic infectious disease with global repercussions. American cutaneous leishmaniasis (ACL) is endemic in southern Brazil and its pathogenesis varies according to parasite species, immune response, and host genetics. In terms of immunogenetics, many host genes, including HLA (human leukocyte antigen), cou.. Read More»

Genet. Mol. Res. 14(4):
2015.November.18.58
DOI:
10.4238/2015.November.18.58
Animal Genetics   Research Article

Isolation and characterization of microsatellite loci in hybrid giant tiger grouper

Authors: Y.S. Huang, Z.B. Li, Y.F. Ning, J.B. Shangguan, Y. Yuan, X.Q. Mao and B.B. Li

The hybrid giant tiger grouper is a fish that has considerable commercial value and has become increasingly important for aquaculture in South East Asia since 2008. In order to prevent any reduction in genetic diversity in hybrid grouper as a result of aquaculture, we have identified 21 microsatellite markers that can be used .. Read More»

Genet. Mol. Res. 14(4):
2015.November.18.35
DOI:
10.4238/2015.November.18.35
Plant Genetics   Research Article

Relationships between four measures of genetic distance and breeding behavior in spring wheat

Authors: G. Benin, G. Matei, A. Costa de Oliveira, G.O. Silva, T.R. Hagemann, C. Lemes da Silva, E.S. Pagliosa and E. Beche

We estimated the genetic distances among 10 spring wheat genotypes based on pedigree data, morphological traits and AFLP markers, used individually and combined with morphological traits, to find the best predictors of general- and specific-combining abilities among parental genotypes. Ten wheat parents were crossed in a diallel form, disregarding recipro.. Read More»

Genet. Mol. Res. 11(3):
2012.June.15.3
DOI:
10.4238/2012.June.15.3