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Gene

Human Genetics   Research Article

Effects of maintaining intravenous infusion of remifentanil or propofol on anesthesia and palinesthesia during anesthesia and analepsia

Authors: X. Zhao, Y.W. Jin, H.B. Li, Z.G. Wang, H. Feng and C. Feng

When recovering from general anesthesia, upon removal of the endotracheal tube, patients may experience a high dynamic response in the circulatory system, along with choking and restlessness. This study was designed to study the effect of maintaining an intravenous infusion of remifentanil or propofol on the performance of gen.. Read More»

Genet. Mol. Res. 13(2):
2014.February.13.8
DOI:
10.4238/2014.February.13.8
Animal Genetics   Research Article

Range-wide phylogeography and conservation genetics of a narrowly endemic stream salamander, Pachyhynobius shangchengensis (Caudata, Hynobiidae): implications for conservation

Authors: T. Pan, H. Wang, C.-C. Hu, W.-B. Shi, K. Zhao, X. Huang and B.-W. Zhang

The Shangcheng stout salamander (Pachyhynobius shangchengensis) is an endangered amphibian endemic to the Dabie Mountains, southeast China, and is currently threatened by habitat loss and illegal poaching. Here we used the mitochondrial DNA control region sequence (768 bp) to conduct a comprehensive investigation of genetic di.. Read More»

Genet. Mol. Res. 13(2):
2014.February.13.9
DOI:
10.4238/2014.February.13.9
Microbial Genetics   Research Article

Gene expression and molecular modeling of the HSP104 chaperone of Trypanosoma cruzi

Authors: R.A. Campos, M.L. da Silva, G.V. da Costa, P.M. Bisch, J.M. Peralta, R. Silva, E. Rondinelli and T.P. ��rm�©nyi

Heat shock protein (HSP) 104 is a highly conserved molecular chaperone that catalyzes protein unfolding, disaggregation and degradation under stress conditions. We characterized HSP104 gene structure and expression in Trypanosoma cruzi, a protozoan parasite that causes Chagas’ disease. The T. cruzi HSP104 is an 869 amino-acid protein encoded by a si.. Read More»

Genet. Mol. Res. 11(3):
2012.August.6.15
DOI:
10.4238/2012.August.6.15
Cytogenomics   Research Article

Impact of climatic factors on genetic diversity of Stipa breviflora populations in Inner Mongolia

Authors: Q. Zhang, J.M. Niu, S.B. Wu, A. Buyantuyev and J.J. Dong

Genetic diversity of Stipa breviflora populations in the Inner Mongolian grasslands of China and its possible correlation with climatic factors was examined using geographic information systems and random amplified polymorphism DNA analysis. A total of 308 bands were produced with 28 arbitrary decamer oligonucleotide. Three major findings were demonstrate.. Read More»

Genet. Mol. Res. 11(3):
2012.August.6.12
DOI:
10.4238/2012.August.6.12
Human Genetics   Research Article

Population structure and genetic diversity in natural populations of Theobroma speciosum Willd. Ex Spreng (Malvaceae)

Authors: L.D. Giustina, L.N. Luz, F.S. Vieira, F.S. Rossi, C.R.A. Soares-Lopes, T.N.S. Pereira and A.A.B. Rossi

The genus Theobroma found in the Amazon region is composed of 22 species, including Theobroma speciosum, better known as cacauí. These species are constantly threatened by forest fragmentation caused by human activities and require conservation strategies and management aimed at preserving them in their natural environm.. Read More»

Genet. Mol. Res. 13(2):
2014.February.14.5
DOI:
10.4238/2014.February.14.5
Microbial Genetics   Research Article

Identification of hybrids between triticale and Aegilops juvenalis (Thell.) Eig and determination of genetic similarity with ISSRs

Authors: A. Gradzielewska, D. Gruszecka, J. LeÃ?Â?niowska-Nowak and E. Paczos-GrzÃ?Â?da

Wide hybridization expands the gene pool of cultivated species and can produce genotypes with practical value, often resistant to diseases. In plants, ISSRs are often used for hybrid identification as well as for diversity evaluation. We estimated genetic similarity among advanced genetic stocks of triticale hybrids and identified Aegilops juvenalis intro.. Read More»

Genet. Mol. Res. 11(3):
2012.July.10.1
DOI:
10.4238/2012.July.10.1
Human Genetics   Research Article

Association of the g.27563G>A osteoprotegerin genetic polymorphism with bone mineral density in Chinese women

Authors: Y.P. Liu, D.W. Zhao, W.M. Wang, B.J. Wang, Y. Zhang and Z.G. Li

Osteoporosis is a common multifactorial disease in postmenopausal women. This study aimed to investigate the association of the g.27563G>A osteoprotegerin (OPG) genetic polymorphism with bone mineral density (BMD) and osteoporosis. A case-control study was carried out with 435 osteoporosis postmenopausal women cases and 442.. Read More»

Genet. Mol. Res. 13(2):
2014.February.14.9
DOI:
10.4238/2014.February.14.9
Microbial Genetics   Research Article

Microarray-based gene expression profiles in rabbit retina due to negative pressure suction

Authors: H.X. Zhao, C.M. Niu and W.Y. Guan

We investigated a possible molecular pathogenesis involving retinal ganglion cell apoptosis following transient high intraocular pressure. Changes in the gene expression profiles of the retina were detected via gene chip methodology. Twelve New Zealand white rabbits were randomly assigned to control and 3-min negative pressure suction groups. The control .. Read More»

Genet. Mol. Res. 11(3):
2012.May.18.9
DOI:
10.4238/2012.May.18.9
Medical Genetics   Research Article

Common variants in the CRP gene are associated with serum C-reactive protein levels and body mass index in healthy individuals in Mexico

Authors: E. Flores-Alfaro, G. Fern�¡ndez-Tilapa, E. Salazar-Mart�­nez, M. Cruz, B. Illades-Aguiar and I. Parra-Rojas

Variants in the C-reactive protein (CRP) gene have been found to be associated with various phenotypic traits. We evaluated the effect of four SNPs in the CRP gene on serum levels of protein and body mass index (BMI) in 150 unrelated Mexican subjects from 18 to 25 years old, without hypertension, non-overweight, and without inflammatory diseases, non-smok.. Read More»

Genet. Mol. Res. 11(3):
2012.May.14.5
DOI:
10.4238/2012.May.14.5
Animal Genetics   Research Article

Single nucleotide polymorphism screening, molecular characterization, and evolutionary aspects of chicken Piwi genes

Authors: H.Z. Wang, T. Ma, G.B. Chang, F. Wan, X.P. Liu, L. Lu, L. Xu, J. Chen and G.H. Chen

The P-element-induced wimpy testis (Piwi) gene is involved in germline stem cell self-renewal, meiosis, RNA silencing, and transcriptional regulation. Piwi genes are relatively well conserved in many species, but their function in poultry species is unclear. In this study, Piwi genes were sequenced u.. Read More»

Genet. Mol. Res. 14(4):
2015.November.18.45
DOI:
10.4238/2015.November.18.45