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Gene

Medical Genetics   Research Article

Result and pedigree analysis of spontaneously abortion villus chromosome detecting by FISH

Authors: N. An, L.-L. Li, X.-Y. Zhang, W.-T. Sun, M.-H. Liu and R.-Z. Liu

The aim of this study was to evaluate the relationship between fetal karyotype and parental chromosomal abnormalities, and to provide a basis for clinical diagnosis and therapy in Northeast China. A total of 144 spontaneously aborted fetuses were analyzed by FISH to test for chromosome number and to recall couples for peripheral blood karyotype analysis. .. Read More»

Genet. Mol. Res. 14(4):
2015.December.11.13
DOI:
10.4238/2015.December.11.13
Microbial Genetics   Research Article

Genes associated with disc degeneration identified using microarray gene expression profiling and bioinformatics analysis

Authors: Y. Chen, K. Chen, M. Li, C. Li, H. Ma, Y.S. Bai, X.D. Zhu and Q. Fu

Disc degeneration is strongly associated with back or neck pain, sciatica, and disc herniation or prolapse. It places an enormous economic burden on society and can greatly affect quality of life. Alternative treatment approaches, such as genetic therapies, are urgently needed to slow or reverse the disc degeneration process. We downloaded gene expression.. Read More»

Genet. Mol. Res. 12(2):
2013.April.26.5
DOI:
10.4238/2013.April.26.5
Human Genetics   Research Article

Genetic diversity in fragmented populations of Populus talassica inferred from microsatellites: implications for conservation

Authors: X.H. Zhu, S.P. Cheng, T. Liao and X.Y. Kang

Populus talassica Kom. is an ecologically important species endemic to central Asia. In China, its main distribution is restricted to the Ili region in the Xinjiang Autonomous Region. An understanding of genetic diversity and population structure is crucial for the development of a feasible conservation strategy. Twenty-six hi.. Read More»

Genet. Mol. Res. 15(2):
gmr.15027899
DOI:
10.4238/gmr.15027899
Human Genetics   Research Article

Evaluation of the stability of reference genes in bone mesenchymal stem cells from patients with avascular necrosis of the femoral head

Authors: X.N. Wang, Q.W. Yang, Z.W. Du, T. Yu, Y.G. Qin, Y. Song, M. Xu and J.C. Wang

This study aimed to evaluate 12 genes (18S, GAPDH, B2M, ACTB, ALAS1, GUSB, HPRT1, PBGD, PPIA, PUM1, RPL29, and TBP) for their reliability and stability as reference sequences for real-time quantitative PCR (RT-qPCR) in bone marrow-derived mesenchymal stem cells (BMSCs) isolated from patients with avascular necrosis of the femo.. Read More»

Genet. Mol. Res. 15(2):
gmr.15027926
DOI:
10.4238/gmr.15027926
Microbial Genetics   Research Article

Peroxidase is involved in Pepper yellow mosaic virus resistance in Capsicum baccatum var. pendulum

Authors: L.S.A. Gon�§alves, R. Rodrigues, M.S.S. Diz, R.R. Robaina, A.T. do Amaral J�ºnior, A.O. Carvalho and V.M. Gomes

Pathogenesis-related proteins (PRs) are among the defense mechanisms of plants that work as an important barrier to the development of pathogens. These proteins are classified into 17 families according to their amino acid sequences, serology, and/or biological or enzyme activity. The present study aimed to identify PRs associated with the pathosystem of .. Read More»

Genet. Mol. Res. 12(2):
2013.April.26.3
DOI:
10.4238/2013.April.26.3
Plant Genetics   Research Article

Selection in sugarcane based on inbreeding depression

Authors: A.A.C. de Azeredo, L.L. Bhering, B.P. Brasileiro, C.D. Cruz and M.H.P. Barbosa

This study aimed to evaluate the gene action associated with yield-related traits, including mean stalk weight (MSW), tons of sugarcane per hectare (TCH), and fiber content (FIB) in sugarcane. Moreover, the viability of individual reciprocal recurrent selection (RRSI-S1) was verified, and the effect of inbreeding depression on.. Read More»

Genet. Mol. Res. 15(2):
gmr.15027965
DOI:
10.4238/gmr.15027965
Human Genetics   Research Article

Relationship between TBX20 gene polymorphism and congenital heart disease

Authors: X.F. Yang, Y.F. Zhang, C.F. Zhao, M.M. Liu, J.P. Si, Y.F. Fang,W.W. Xing and F.L. Wang

Congenital heart disease in children is a type of birth defect. Previous studies have suggested that the transcription factor, TBX20, is involved in the occurrence and development of congenital heart disease in children; however, the specific regulatory mechanisms are yet to be evaluated. Hence, this study aimed to evaluate th.. Read More»

Genet. Mol. Res. 15(2):
gmr.15027374
DOI:
10.4238/gmr.15027374
Human Genetics   Research Article

Gene expression and enzyme activity of lipoprotein lipase correlate with intramuscular fat content in Guangxi san-huang and Arbor Acres chickens

Authors: Y.N. Huang, J. Wang, B.J. Chen, Q.Y. Jiang, Y.F. Guo, G.Q. Lan and H.S. Jiang

Lipoprotein lipase (LPL) is a key enzyme in lipid metabolism. This study investigated LPL gene expression, LPL enzyme activity, and the correlation of each with intramuscular fat (IMF) in Chinese Guangxi san-huang (GXSH) and Arbor Acres (AA) chickens. The results showed that age and breed had significant effects on LPL express.. Read More»

Genet. Mol. Res. 15(2):
gmr.15027414
DOI:
10.4238/gmr.15027414
Medical Genetics   Research Article

Molecular phylogeny of Lathyrus species: insights from sequence-related amplified polymorphism markers

Authors: S. Marghali, A. Touati, M. Gharbi, D. Sdouga and N. Trifi-Farah

Sequence-related amplified polymorphism (SRAP) markers were used to evaluate the intra- and interspecific variation among 40 Lathyrus genotypes (four species) (Fabaceae). Ten SRAP primer combinations resulted in a total of 94 bands, and they exhibited high interspecific variability. The genetic differentiation among Lathyrus, estimated using AMOVA, was hi.. Read More»

Genet. Mol. Res. 15(1):
gmr.15017198
DOI:
10.4238/gmr.15017198
Plant Genetics   Research Article

Genetic variation in Rhodomyrtus tomentosa (Kemunting) populations from Malaysia as revealed by inter-simple sequence repeat markers

Authors: T.S. Hue, T.L. Abdullah, N.A.P. Abdullah and U.R. Sinniah

Kemunting (Rhodomyrtus tomentosa) from the Myrtaceae family, is native to Malaysia. It is widely used in traditional medicine to treat various illnesses and possesses significant antibacterial properties. In addition, it has great potential as ornamental in landscape design. Genetic variability studies are important for the rational management and conserv.. Read More»

Genet. Mol. Res. 14(4):
2015.December.14.10
DOI:
10.4238/2015.December.14.10