Gene
Genomic cloning, expression, and single nucleotide polymorphism association analysis of the insulin-like androgenic gland hormone gene in the oriental river prawn (Macrobrachium nipponense)
Authors: F.J. Li, F.W. Jiang, H.K. Bai, H.T. Fu, S.B. Jin, S.M. Sun, H. Qiao and W.Y. Zhang
Increasing evidence suggests that the insulin-like androgenic gland hormone (IAG) gene plays an important role in male sexual differentiation, metabolism, and growth in crustaceans. In the present study, we isolated the full-length genome sequence of IAG by genome walking based on the cDNA sequence in Macrobrachium nipponense. Four novel single nucleotide.. Read More»
- Genet. Mol. Res. 14(2):
- 2015.June.1.8
- DOI:
- 10.4238/2015.June.1.8
Position effect variegation and epigenetic modification of a transgene in a pig model
Authors: Z. Yin, Q.R. Kong, Z.P. Zhao, M.L. Wu, Y.S. Mu, K. Hu1 and Z.H. Liu
Sequences proximal to transgene integration sites are able to regulate transgene expression, resulting in complex position effect variegation. Position effect variegation can cause differences in epigenetic modifications, such as DNA methylation and histone acetylation. However, it is not known which factor, position effect or.. Read More»
- Genet. Mol. Res. 11(1):
- 2012.February.16.1
- DOI:
- 10.4238/2012.February.16.1
Genetic variants on 17q21 are associated with asthma in a Han Chinese population
Authors: F.-X. Li, J.-Y. Tan, X.-X. Yang, Y.-S. Wu, D. Wu and M. Li
A genome-wide study has shown an association between SNPs located on 17q21 and asthma. Such associations have been identified in several populations, but little is known about the Han Chinese population. We conducted a case-control study in a Han Chinese population to investigate the relationship between SNPs located on 17q21 .. Read More»
- Genet. Mol. Res. 11(1):
- 2012.February.10.5
- DOI:
- 10.4238/2012.February.10.5
Discrimination of common bean cultivars using multiplexed microsatellite markers
Authors: P.C.B. Cardoso, C. Brondani, I.P.P. Menezes, P.A.M.R. Valdisser, T.C.O. Borba,, M.J. Del Peloso and R.P. Vianello
Analysis of DNA polymorphisms allows for the genetic identification and precise discrimination of species with a narrow genetic base such as common bean. The primary objectives of the present study were to molecularly characterize commercial common bean varieties developed at various research institutions using microsatellite .. Read More»
- Genet. Mol. Res. 13(1):
- 2014.March.24.1
- DOI:
- 10.4238/2014.March.24.1
Cloning and molecular modeling of Litopenaeus vannamei (Penaeidae) C-type lectin homologs with mutated mannose binding domain-2
Authors: F.H.F. Costa, N.S.M.S. Valen�§a, A.R.B.P. Silva, G.A. Bezerra4, B.S. Cavada and G. R�¡dis-Baptista
C-type lectins are animal proteins that contain at least one carbohydrate recognition domain (CRD) capable of mediating sugar and calcium binding. Carbohydrate recognition is directly required for some biological functions, including the innate immune response. We cloned two novel C-type lectin (CTL) precursors from the commer.. Read More»
- Genet. Mol. Res. 10(2):
- vol10-2gmr999
- DOI:
- 10.4238/vol10-2gmr999
Genetic structure based on nuclear and chloroplast microsatellite loci of Solanum lycocarpum A. St. Hil. (Solanaceae) in Central Brazil
Authors: K. Martins, L.J. Chaves, R. Vencovsky and P.Y. Kageyama
Solanum lycocarpum (Solanaceae) is a woody species found in the Brazilian Cerrado. The flowers are pollinated by Xylocopa spp bees, and seeds are dispersed by mammals with distinct home range sizes. As a consequence, relative contributions of pollen and seeds to overall gene flow can vary according to different spatial scales... Read More»
- Genet. Mol. Res. 10(2):
- vol10-2gmr1046
- DOI:
- 10.4238/vol10-2gmr1046
Positions of pluripotency genes and hepatocyte-specific genes in the nucleus before and after mouse ES cell differentiation
Authors: K. Udagawa and T. Ohyama,
Spatial positioning of genes in the cell nucleus plays an important role in the regulation of genomic functions. Evidence for changes in gene positioning associated with transcriptional activity has been reported. However, our understanding of this phenomenon is still quite limited. We examined how pluripotency genes and hepat.. Read More»
- Genet. Mol. Res. 13(1):
- 2014.March.24.2
- DOI:
- 10.4238/2014.March.24.2
Differential gene expression and functional analysis of pit cells from regenerating rat liver
Authors: C.S. Xu, X.G. Chen, C.F. Chang, G.P. Wang, W.B. Wang, L.X. Zhang, Q.S. Zhu and L. Wang
Hepatic pit cells are a population of large granular lymphocytes that substantially contribute to hepatic immunity. Studies have proven that pit cells have a role in liver regeneration, but the details of the relationship between pit cells and liver regeneration is not clear at present. We subjected rats to a two-third hepatectomy; pit cells with high pur.. Read More»
- Genet. Mol. Res. 10(2):
- vol10-2gmr1052
- DOI:
- 10.4238/vol10-2gmr1052
Polymorphism of somatostatin gene and its association with growth traits in Chinese cattle
Authors: L. Gao, L.S. Zan, H.B. Wang, R.J. Hao and X. Zhong
Somatostatins play a crucial role in the regulation of growth and development in vertebrates, especially muscle growth. We assessed the association of somatostatin gene polymorphisms with growth traits by PCR-SSCP (polymerase chain reaction-single strand conformation polymorphism) and DNA sequencing methods in 694 individuals .. Read More»
- Genet. Mol. Res. 10(2):
- vol10-2gmr1029
- DOI:
- 10.4238/vol10-2gmr1029
Association between �²1 adrenergic receptor gene Arg389Gly polymorphism and risk of heart failure: a meta-analysis
Authors: S.T. Ma, W. Zhao,B. Liu, R.Y. Jia, C.J. Zhao and L.Q. Cui
Numerous studies have evaluated the association between Arg389Gly polymorphism in the β1 adrenergic receptor gene and heart failure risk. However, the specific association is still controversial. We performed a meta-analysis of all case-control studies that evaluated the association between Arg389Gly polymorphism and heart failure in humans. Studies .. Read More»
- Genet. Mol. Res. 14(2):
- 2015.June.1.9
- DOI:
- 10.4238/2015.June.1.9