Authors: G.E. Yu, S. Kwon, J.H. Hwang, S.M. An, D.H. Park, D.G. Kang, T.W. Kim, I.-S. Kim, H.C. Park, J. Ha and C.W. Kim
Cell death-inducing DFF45-like effector (CIDE) B is a member of the CIDE family of apoptosis-inducing factors. In the present study, we detected a single nucleotide polymorphism (SNP), c.414G>A, which corresponds to the synonymous SNP 414Arg, in CIDE-B in the Berkshire pigs. We also analyzed the relationships between the CI.. Read More»
Authors: L.R. Ruschel, V.M. Schmitt, A.B. Silva, C.S.A. Oliveira, K. Flach, D.O. dâ??Avila and F.V. Thiesen
Mycophenolate mofetil (MMF) is a prodrug active only after its hydrolysis to mycophenolic acid (MPA). The UGT1A9 enzyme is of special interest since it is the main enzyme involved in the glucuronidation of MPA. Single nucleotide polymorphisms (SNPs) in the UGT1A9 gene may be responsible for individual differences in the pharma.. Read More»
Authors: S.V. ?lvares-Carvalho, R. Silva-Mann, I.B. Gois, M.F.V. Melo, A.S. Oliveira, R.A. Ferreira and L.J. Gomes
The success of recovery programs on degraded areas is dependent on the genetic material to be used, which should present heterozygosity and genetic diversity in native and recovered populations. This study was carried out to evaluate the model efficiency to enable the recovery of a degraded area of the Lower São Francis.. Read More»
Authors: M.M. Oliveira, L.B. Sousa, M.C. Reis, E.G. Silva Junior, D.B.O. Cardoso, O.T. Hamawaki and A.P.O. Nogueira
The genetic diversity study has paramount importance in breeding programs; hence, it allows selection and choice of the parental genetic divergence, which have the agronomic traits desired by the breeder. This study aimed to characterize the genetic divergence between 24 soybean genotypes through their agronomic traits, using .. Read More»
Authors: E.S.S. Hoogerheide, J.A. Azevedo Filho, R. Vencovsky, M.I. Zucchi, B.W. Zago and J.B. Pinheiro
The cultivated garlic (Allium sativum L.) displays a wide phenotypic diversity, which is derived from natural mutations and phenotypic plasticity, due to dependence on soil type, moisture, latitude, altitude and cultural practices, leading to a large number of cultivars. This study aimed to evaluate the genetic variability sho.. Read More»
Authors: J.H. Hu1,2*, F.Y. Zhang1*, K.J. Jiang1, Y.B. Fang1,2, J. Wang1,2, M. Zhao1,2, Z.G. Qiao1 and L.B. Ma1
The thioredoxin (Trx) system consists of thioredoxin reductase (TrxR), Trx, and nicotinamide adenine dinucleotide phosphate (NADPH). TrxR is an NADPH-dependent oxidoreductase. Trx is a ubiquitous small protein with a redox-active disulfide bridge that plays important regulatory roles in some vital metabolic reactions. In this study, a cDNA sequence (SpTrx.. Read More»
Authors: Q.Y. Yang1, J.H. Li2, Q.Y. Wang3, Y. Wu3, J.L. Qin3, J.J. Cheng3 and J. Qiu3
We examined whether metastasis-associated gene 1 (MTA1) promotes cell proliferation via DNA damage repair in ovarian cancer. MTA1 was successfully down-regulated using small interfering RNA in the epithelial ovarian cancer cell lines SKOV-3 and OVCAR-3. Cell growth was evaluated through MTT and colony formation assays. Fluorescence-activated cell sorting .. Read More»
Authors: F. Yu1, S. Huang2, F. Zhou2, Q. Luo2, X. Xie3 and C. Zheng2
We examined patients of Han nationality diagnosed with irritable bowel syndrome with diarrhea (IBS-D) in Guangdong, China, to analyze the correlation between DQB1 allele polymorphisms and the genetic susceptibility to IBS-D. A total of 120 IBS-D patients of Han nationality in Guangdong, China, and 60 healthy control volunteers were included. DQB1 allele p.. Read More»
Authors: R. Su1, W. Sun1, D. Li1, Q.Z. Wang1, X.Y. Lv1, H.H. Musa2, L. Chen3, Y.F. Zhang3 and W.Z. Wu3
The aim of the present study was to detect delta-like 1 homolog (DLK1) and insulin-like growth factor-I (IGF-I) gene expression in the longissimus dorsi of Hu sheep at different growth stages and study the association between these genes and meat quality... Read More»
Authors: S.R. Guilherme1, M.A.P. Ramalho1, A. de F.B. Abreu2 and L.A. Pereira1
The number of pods per common bean plant is a primary component of grain yield, which depends on the number of flowers produced and on the flower set. Thus, a larger number of flowers per plant would increase yield. Lines with inflorescences that had a large number of flowers compared to common bean plants now under cultivation were identified. We analyze.. Read More»