Gene
Standardization of a molecular method for epidemiologic identification of Leishmania strains
Authors: R.F. Rocha, E.V. Menezes, A.R.E.O. Xavier, V.A. Royo, D.A. Oliveira, A.F.M. J�ºnior, E.S. Dias, A.C.V.M.R. Lima and E.M. Michalsky
Molecular studies of the evolutionary relationships among Leishmania species suggest the presence of high genetic variation within this genus, which has a direct effect on public health in many countries. The coexistence of species in a particular region can result in different leishmaniasis clinical forms and treatment respon.. Read More»
- Genet. Mol. Res. 15(4):
- gmr.15048854
- DOI:
- 10.4238/gmr.15048854
14-3-3 Gene expression in regenerating rat liver after 2/3 partial hepatectomy
Authors: D.M. Xue, X.Q. Guo, R. Chen, Z.P. Niu and C.S. Xu
14-3-3 Proteins are a ubiquitous family of molecules that participate in protein kinase signaling pathways in all eukaryotic cells. Functioning as phosphoserine/phosphothreonine-binding modules, 14-3-3 proteins participate in the phosphorylation-dependent protein-protein interactions that control progression through the cell cycle, initiation and.. Read More»
- Genet. Mol. Res. 14(1):
- 2015.March.20.12
- DOI:
- 10.4238/2015.March.20.12
High-resolution melting curve analysis of the ADSL and LPL genes and their correlation with meat quality and blood parameters in chickens
Authors: X.D. Zhang, Q.H. Li, L.F. Lou, J. Liu, X.H. Chen, C.X. Zhang and H.H. Wang
Adenylosuccinate lyase (ADSL) and lipoprotein lipase (LPL) are key enzymes in the metabolism of inosine monophosphate (IMP) and fat mass, which are important factors in meat quality evaluation. In this study, we selected 50 hens from the ISA B-line layers and Guangxi Yellow chickens, slaughtered the chickens at 120 days old, and analyzed polymorphisms in .. Read More»
- Genet. Mol. Res. 14(1):
- 2015.March.20.13
- DOI:
- 10.4238/2015.March.20.13
Naturally fragmented but not genetically isolated populations of Podocarpus sellowii Klotzsch (Podocarpaceae) in southeast Brazil
Authors: F.R. Gon�§alves, F.A. Vieira and D. Carvalho
In southeastern Brazil, the majority of the riparian ecosystems are fragmented and degraded mainly due to human activities. The perennial gymnosperm Podocarpus sellowii Klotzch is a typical tree species from a gallery forest in the rupestrian area. Ten alloenzymatic loci were used to estimate the allelic frequency of 232 indiv.. Read More»
- Genet. Mol. Res. 15(4):
- gmr.15048871
- DOI:
- 10.4238/gmr.15048871
Gene expression profile analysis of testis and ovary of oriental river prawn, Macrobrachium nipponense, reveals candidate reproduction-related genes
Authors: H. Qiao, Y.W. Xiong, S.F. Jiang, H.T. Fu, S.M. Sun, S.B. Jin, Y.S. Gong and W.Y. Zhang
This study utilized high-throughput RNA sequencing technology to identify reproduction- and development-related genes of Macrobrachium nipponense by analyzing gene expression profiles of testis and ovary. More than 20 million 1 x 51-bp reads were obtained by Illumina sequencing, generating more than 7.7 and 11.7 million clean reads in the testis and ovary.. Read More»
- Genet. Mol. Res. 14(1):
- 2015.March.20.14
- DOI:
- 10.4238/2015.March.20.14
Sequence variation and gene duplication at the MHC DRB loci of the spotted seal Phoca largha
Authors: X.G. Gao, J.B. Han, Z.C. Lu, P.J. Zhang and C.B. He
The major histocompatibility complex (MHC) is one of the most important genetic systems associated with resistance to infectious diseases in vertebrates. The spotted seal (Phoca largha) is one of the most endangered species in China. In this study, we present the first step in the molecular characterization of a DRB-like locus in the spotted seal by analy.. Read More»
- Genet. Mol. Res. 14(1):
- 2015.March.20.15
- DOI:
- 10.4238/2015.March.20.15
Complete mitochondrial genome of the Cyclemys dentata and phylogenetic analysis of the major family Geoemydidae
Authors: Y.N. Huang, J. Li, Q.Y. Jiang, X.S. Shen, X.Y. Yan, Y.B. Tang, J. Huang, Y.F. Guo, G.Q. Lan and H.S. Jiang
In the present study, the complete mitochondrial (mt) genome of Cyclemys dentata was determined using PCR reactions. The structural organization and gene order of C. dentata were equivalent to those of most other vertebrates. The mt genome was 16,489 bp in length, has rich A+T content, consisting of 13 protein-coding genes, 2 ribosomal RNA genes, 22 trans.. Read More»
- Genet. Mol. Res. 14(2):
- http://dx.doi.org/2015.April.13.2
- DOI:
- http://dx.doi.org/10.4238/2015.April.13.2
Protein-protein interaction network and mechanism analysis of hepatitis C
Authors: Y. Tang, Q. Tang, C. Dong, X. Li, Z. Zhang and F. An
We predicted potential genes and identified pathways associated with hepatitis C. The gene expression profiles of GSE40184 from blood samples and GSE38597 from liver biopsy samples were downloaded from the GEO database. Differentially expressed genes (DEGs) were recognized using the Limma Package. The Pearson correlation test was used to construct the co-.. Read More»
- Genet. Mol. Res. 14(1):
- 2015.March.20.17
- DOI:
- 10.4238/2015.March.20.17
Genetic characterization of natural populations of the medicinal plant Palicourea coriacea (Rubiaceae) with molecular markers
Authors: T.C.S. Barbosa, S.T. Sibov, M.P.C. Telles and T.N. Soares
Palicourea coriacea (Rubiaceae) is a herbaceous, perennial species typical of the Cerrado; it is popularly known as “douradinha”, because of its yellow flowers. It is utilized in popular medicine, mainly for the treatment of renal diseases. We used RAPD markers to evaluate the genetic structure of nine natural popu.. Read More»
- Genet. Mol. Res. 9(2):
- vol9-2gmr671
- DOI:
- 10.4238/vol9-2gmr671
Influence of neural stem cell transplantation on angiogenesis in rats with spinal cord injury
Authors: Z. Li, G.-H. Guo, G.-S. Wang, C.-X. Guan and L. Yue
We examined the influence of neural stem cell transplantation on angiogenesis in rats with spinal cord injury. Sixty rats with spinal cord injury were divided into an experimental group and a control group and given neural stem cells or an equivalent amount of phosphate-buffered saline by intravenous transplantation, respectiv.. Read More»
- Genet. Mol. Res. 13(3):
- 2014.August.7.23
- DOI:
- 10.4238/2014.August.7.23