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Gene

Animal Genetics   Research Article

Environmental and genetic factors affecting the weaning-estrus interval in sows

Authors: C.D.S. Leite, J.F. Lui, L.G. Albuquerque and D.N.M. Alves

We examined the effects of environmental and genetic factors on the weaning-to-estrus interval (WEI) in sows. In order to perform the analyses of the environmental factors, 8104 observations of the 1st to the 6th WEI were carried out, while 6548 observations of the 1st to the 3rd WEI were carried out for the analyses of geneti.. Read More»

Genet. Mol. Res. 10(4):
2011.November.4.2
DOI:
10.4238/2011.November.4.2
Human Genetics   Research Article

Genetic differentiation of octopuses from different habitats near the Korean Peninsula and eastern China based on analysis of the mDNA cytochrome C oxidase 1 gene

Authors: J.-H. Kang J.-Y. Park T.-J. Choi

Distributed along the coastal waters of Korea and China, Octopus minor is found in various habitats, including the mud flats in the southern and western coasts of the Korean Peninsula and the rocky areas around Jeju Island; however, the genetic relationships among the different populations are unknown and have not been studied. We compared 630-nucleotide seq.. Read More»

Genet. Mol. Res. 11(4):
2012.November.21.2
DOI:
10.4238/2012.November.21.2
Cytogenomics   Research Article

Role of CASP-10 gene polymorphisms in cancer susceptibility: a HuGE review and meta-analysis

Authors: S. Yan Y.Z. Li J.W. Zhu C.L. Liu P. Wang Y.L. Liu

We investigated a possible association between CASP-10 gene polymorphisms and susceptibility to cancer through a meta-analysis. Eight studies with a total of 29,936 cancer cases and 34,041 healthy controls were included. Meta-analysis results showed that the rs13006529*T carrier was significantly associated with increased cancer risk (OR = 1.17, 95%CI = 1.01.. Read More»

Genet. Mol. Res. 11(4):
2012.November.26.1
DOI:
10.4238/2012.November.26.1
Cytogenomics   Research Article

DNA extraction from fixed cytogenetic cell suspensions

Authors: Amorim MR, Vargas FR, Llerena Junior JC and Pombo-de-Oliveira MS

We developed a procedure for DNA extraction from small volumes of fixed cell suspensions previously prepared for conventional cytogenetic analysis. Good quality DNA was isolated with a fast and simple protocol using DNAzol reagent. This provided suitable DNA for various types of molecular analyses, including polymerase chain r.. Read More»

Genet. Mol. Res. 6(3):
Human Genetics   Research Article

Association between IL-1�± rs17561 and IL-1�² rs1143634 polymorphisms and periodontitis: a meta-analysis

Authors: W.T. Yin, Y.P. Pan and L. Lin

Genetic variations in human interleukin-1 (IL-1) genes are known to be involved in inflammatory disorders. The rs17561 and rs1143634 polymorphisms of IL-1α and IL-1β, respectively, have been increasingly recognized as important regulators in the development of periodontitis. However, the existence of a specific association remains controversial.. Read More»

Genet. Mol. Res. 15(1):
gmr.15017325
DOI:
10.4238/gmr.15017325
Plant Genetics   Research Article

Genetic diversity in a germplasm bank of Oenocarpus mapora (Arecaceae)

Authors: E.F. Moura M.S.P. de Oliveira

Oenocarpus mapora is an Amazonian palm species commonly used by native populations for food and in folk medicine. We measured genetic variability, using RAPD markers, of material kept in a germplasm bank composed of accessions sampled from the Brazilian Amazon. These included 74 individuals from 23 accessions sampled from 9 localities in three States of t.. Read More»

Genet. Mol. Res. 11(4):
2012.November.26.2
DOI:
10.4238/2012.November.26.2
Animal Genetics   Research Article

Inhibition of vascular endothelial growth factor A expression in mouse granulosa cells by lentivector-mediated RNAi

Authors: N. Ally X.L. Zou B.C. Jiang L. Qin L. Zhai P. Xiao H.L. Liu

Vascular endothelial growth factor (VEGF) has been found responsible for the induction of proliferation and differentiation in granulosa cells. We constructed four short hairpin RNA (shRNA) expression plasmids targeting the mouse VEGFA gene, and examined their effect on VEGF expression in mouse granulosa cells (MGC) in vitro. Four different shRNA oligonuc.. Read More»

Genet. Mol. Res. 11(4):
2012.November.28.1
DOI:
10.4238/2012.November.28.1
Animal Genetics   Research Article

AGPAT6 polymorphism and its association with milk traits of dairy goats

Authors: C. He, C. Wang, Z.H. Chang, B.L. Guo, R. Li, X.P. Yue, X.Y. Lan, H. Chen and C.Z. Lei

As one of the eight members in the 1-acylglycerol-3-phosphate-O-acyltransferase (AGPATs) family, AGPAT6 is a crucial enzyme for the biosynthesis of glycerolipids and triacylglycerol in eukaryotes, as well as catalyzing the conversion from lysophosphatidic acid to phosphatidic acid. AGPAT6 can be considered as a candidate gene .. Read More»

Genet. Mol. Res. 10(4):
2011.November.4.8
DOI:
10.4238/2011.November.4.8
Plant Genetics   Research Article

Variability and inbreeding in semiexotic maize populations

Authors: A.S. Oliveira, J.B. Miranda Filho and E.F. Reis

Three semiexotic populations (CRE-01, CRE-02, CRE-03) obtained by incorporation of exotic germplasm (lines from CIMMYT, Colombia; selected for resistance to corn stunt complex) were evaluated in two cycles of recurrent selection with half-sib families. In cycle-I, samples comprising 50, 70, and 50 half-sib families were evaluated at Jataí (GO) and .. Read More»

Genet. Mol. Res. 14(1):
2015.February.6.21
DOI:
10.4238/2015.February.6.21
Cytogenomics   Research Article

Development and characterization of DNA microsatellite primers for buriti (Mauritia flexuosa L.f.)Development and characterization of DNA microsatellite primers for buriti (Mauritia flexuosa L.f.)

Authors: Development and characterization of DNA microsatellite primers for buriti (Mauritia flexuosa L.f.)

Mauritia flexuosa L. (Arecaceae) is a palm tree species known as buriti that occurs in the Cerrado biome. It is characteristic of the vereda, a typical ecosystem of central Brazil. In this phytophysiognomy, M. flexuosa and other groups of arboreal-herbaceous species develop in open fields with very humid soils. M. flexuosa can be found in forest borders a.. Read More»

Genet. Mol. Res. 11(4):
2012.September.17.6
DOI:
10.4238/2012.September.17.6