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Effect of You-Gui-Wan on endometrial angiogenesis in controlled ovarian hyperstimulation mice model
Authors: Qiao-zhi Yin, Ji-Zhong Zhang, Li-min Li�Yu-lin Li, Li Huang, Nan Ning
Purpose: To explore the mechanism of You-Gui-Wan (YGW) in improving endometrial receptivity in mouse model of controlled ovarian hyperstimulation (COH). Methods: Sixty female mice with two consecutive oestrous cycles were randomly divided into COH model group (n = 50) and normal control group (n = 10). The COH model was crea.. Read More»
- Genet. Mol. Res. 16(4):
- gmr16039833
- DOI:
- 10.4238/gmr16039833
Anthropization as a determinant factor in the genetic structure of Copernicia prunifera (Arecaceae)
Authors: L.G. Pinheiro, K.P.T. Chagas, A.S.M. Freire, M.C. Ferreira,C.G. Fajardo and F.A. Vieira
This study uses ISSR molecular markers to characterize the demographic pattern, and spatial genetic structure (SGS) at different life stages of development (cohorts) in a natural population of Copernicia prunifera in the Rio Grande do Norte State, Brazil. All individuals were sampled and georeferenced in a 0.55-ha plot. The de.. Read More»
- Genet. Mol. Res. 16(3):
- gmr16039768
- DOI:
- 10.4238/gmr16039768
Critical evaluation of transcription factor Atf2 as a candidate modulator of alcohol preference in mouse and human populations
Authors: L.S. Wang, Y. Jiao, Y. Huang, X.Y. Liu, G. Gibson, B. Bennett,K.M. Hamre, D.W. Li, H.Y. Zhao, J. Gelernter, H.R. Kranzler,L.A. Farrer, L. Lu, Y.J. Wang, W.K. Gu
In prior work, congenic strains carrying the DBA/2Igb (D2) region of chromosome 2 (Chr2) for alcohol preference were bred onto a C57BL/6Ibg (B6) background and as predicted were found to reduce voluntary consumption. Subsequently, interval-specific congenic recombinant strains (ISCRS) were generated and also tested. These ISCR.. Read More»
- Genet. Mol. Res. 12(4):
- 2013.November.26.9
- DOI:
- 10.4238/2013.November.26.9
Roles of Fas/Fasl, Bcl-2/Bax, and Caspase-8 in rat nonalcoholic fatty liver disease pathogenesis
Authors: C.P. Li, J.H. Li, S.Y. He, P. Li and X.L. Zhong
The aim of this study was to investigate the roles of Fas/FasL, Bcl-2/Bax, and Caspase-8 mRNA expressions in nonalcoholic fatty liver disease (NAFLD). The apoptosis percentage was measured by flow cytometry, the immunohistochemical assay was performed for the determination of Fas, FasL, Bcl-2, and Bax expressions, and a real-t.. Read More»
- Genet. Mol. Res. 13(2):
- http://dx.doi.org/2014.May.23.10
- DOI:
- http://dx.doi.org/10.4238/2014.May.23.10
Association between alcohol dehydrogenase 1C gene *1/*2 polymorphism and pancreatitis risk: a meta-analysis
Authors: F. Fang, J. Pan, G.H. Su, L.X. Xu, G. Li, Z.H. Li, H. Zhao and J. Wang
Numerous studies have focused on the relationship between alcohol dehydrogenase 1C gene (ADH1C) *1/*2 polymorphism (Ile350Val, rs698, also known as ADH1C *1/*2) and pancreatitis risk, but the results have been inconsistent. Thus, we conducted a meta-analysis to more precisely estimate this associati.. Read More»
- Genet. Mol. Res. 14(4):
- 2015.November.30.2
- DOI:
- 10.4238/2015.November.30.2
Expression of catalase, alcohol dehydrogenase, and malate dehydrogenase in rot grains upon fungicide use on maize hybrids grown at different spacings
Authors: E.R. Kluge, M.C. Mendes, M.V. Faria, H.O. Santos, L.A. Santos and I.E. Sandini
In this study, we evaluated the fungicide effect on the incidence of rot grains and expression of catalase (CAT), alcohol dehydrogenase (ADH), and malate dehydrogenase (MDH) enzymes in commercial maize hybrids grown with conventional and reduced spacing in Guarapuava, PR, Brazil. The experiment was designed in random blocks wi.. Read More»
- Genet. Mol. Res. 16(2):
- gmr16029634
- DOI:
- 10.4238/gmr16029634
Association between adiponectin gene T45G polymorphism and nonalcoholic fatty liver disease risk: a meta-analysis
Authors: W. Zhang1, L.Q. Zhu1, X.L. Huo2, J. Qin2 and G.Y. Yuan3
Numerous epidemiological investigations have evaluated the association between adiponectin gene T45G polymorphism and risk of nonalcoholic fatty liver disease (NAFLD). However, the results of these studies have proven to be inconsistent. Therefore, we conducted a meta-analysis to obtain a more accurate estimation of this association. Published articles we.. Read More»
- Genet. Mol. Res. 15(1):
- gmr.15017190
- DOI:
- 10.4238/gmr.15017190
Cohn process influences the functional anticoagulant activity of human protein C
Authors: Z.K. Wang, X. Du1, Y.M. Wang, C.Q. Li, F.Z. Lin, H.J. Cao, S.L. Ye, J.J. Hu and J. Yuan
Cohn fraction IV (CFIV) is a byproduct of a plasma fractionation process known as the Cohn process. It is an inexpensive source of protein C, retaining about 90% of protein C (PC) in human plasma. We investigated whether PC is affected during the Cohn process and evaluated correlations among coagulant activity, amidolytic activity and PC antigen during the C.. Read More»
- Genet. Mol. Res. 14(1):
- 2015.February.2.10
- DOI:
- 10.4238/2015.February.2.10
Decoherence in yeast cell populations and its implications for genome-wide expression noise
Authors: M.R.S. Briones F. Bosco
Gene expression “noise” is commonly defined as the stochastic variation of gene expression levels in different cells of the same population under identical growth conditions. Here, we tested whether this “noise” is amplified with time, as a consequence of decoherence in global gene expression profiles (.. Read More»
- Genet. Mol. Res. 8(1):
- vol8-1gmr531
- DOI:
- 10.4238/vol8-1gmr531
Role of APN and TNF-�± in type 2 diabetes mellitus complicated by nonalcoholic fatty liver disease
Authors: X. Lin, Z. Zhang, J.M. Chen, Y.Y. Xu, H.R. Ye, J. Cui, Y. Fang,Y. Jin, D.R. Zhu and L. Yuan
Non-alcoholic fatty liver disease (NAFLD) is a chronic liver disease caused by non-excessive alcohol consumption and is the most common cause of elevated levels of serum liver enzymes. We examined changes in adiponectin (APN) and tumor necrosis factor-a (TNF-a) in type 2 diabetes mellitus (T2DM) complicated by NAFLD and their relationships with insulin resis.. Read More»
- Genet. Mol. Res. 14(2):
- http://dx.doi.org/2015.April.10.1
- DOI:
- http://dx.doi.org/10.4238/2015.April.10.1