
Authors: T.N. Wang, T.J. Li, G.F. Shao and S.X. Wu
Microarray technology is a powerful tool for human genetic research and other biomedical applications. Numerous improvements to the standard K-means algorithm have been carried out to complete the image segmentation step. However, most of the previous studies classify the image into two clusters. In this paper, we propose a novel K-means algorithm, which .. Read More»
Authors: E.S. Assis, A. Rubio Neto, P.D.S. Cabral, F.G. Silva, L.R. Lima and S.C. Vasconcelos Filho
Mouriri elliptica (Mart.) is a genetic resource of the Cerrado domain, which has potential for food and medicinal use. A few studies have been performed on its in vitro propagation, and no studies have examined dissimilarities between plants of this species when cultivated in situ or in vitro. Therefore, the objective of the p.. Read More»
Authors: Tie Koide, Silvia M. Salem-Izacc, Suely L. Gomes and Ricardo Z.N. VĂ?ÂȘncio
SpotWhatR is a user-friendly microarray data analysis tool that runs under a widely and freely available R statistical language (http://www.r-project.org) for Windows and Linux operational systems. The aim of SpotWhatR is to help the researcher to analyze microarray data by providing basic tools for data visualization, normali.. Read More»
Authors: R.G. Freitas, R.F. Missio, F.S. Matos, M.D.V. Resende and L.A.S. Dias
Jatropha curcas, internationally and locally known, respectively, as physic nut and pinhão manso, is a highly promising species for biodiesel production in Brazil and other countries in the tropics. It is rustic, grows in warm regions and is easily cultivated. These characteristics and high-quality oil yields from the s.. Read More»
Authors: S.A.P. Pinto and J.M. Ortega
Following sequence alignment, clustering algorithms are among the most utilized techniques in gene expression data analysis. Clustering gene expression patterns allows researchers to determine which gene expression patterns are alike and most likely to participate in the same biological process being investigated. Gene express.. Read More»
Authors: M.S. Lauretto, C.A.B. Pereira and J.M. Stern
Gene clustering is a useful exploratory technique to group together genes with similar expression levels under distinct cell cycle phases or distinct conditions. It helps the biologist to identify potentially meaningful relationships between genes. In this study, we propose a clustering method based on multivariate normal mixt.. Read More»
Authors: F. Chen, J. Liu, M. Fan, X.M. Wei, Y.L. Xie, L.H. Wang and H. Yang
This study sought to identify and characterize the function of genes as diagnostic markers for Epstein-Barr virus (EBV)-related nasopharyngeal cancer (NPC). The gene expression profile of GSE13597 was downloaded from the Gene Expression Omnibus database, which included 28 EBV-related NPC gene expression profile data sets, 25 d.. Read More»
Authors: E.C.M. Lanes, J.M.S. Viana, G.P. Paes, M.F.B. Paula, C. Maia, E.T. Caixeta and G.V. Miranda
The objectives of this study were to identify the population structure and to assess the genetic diversity of maize inbreds. We genotyped 81 microsatellite loci of 90 maize inbreds that were derived from tropical hybrids and populations. The population structure analysis was based on a Bayesian approach. Each subpopulation was.. Read More»
Authors: F. Liu, L. Yang, Z.Z. Tian, P. Wu and S.L. Sun
Two genes can be co-regulated and possibly have the similar function if they are similarly expressed, which provides a theoretical basis for construction of gene regulatory networks using gene expression data. Herein, a new method of gene regulatory network was constructed based on biclusters in this paper. Given a bicluster, .. Read More»
Authors: J.P. Bao and R.Y. Yuan
DNA data are important in the bioinformatic domain. To extract useful information from the enormous collection of DNA sequences, DNA clustering is often adopted to efficiently deal with DNA data. The alignment-free method is a very popular way of creating feature vectors from DNA sequences, which are then used to compare DNA similarities. This paper propo.. Read More»