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Clustering

Bioinformatics   Research Article

An improved K-means clustering method for cDNA microarray image segmentation

Authors: T.N. Wang, T.J. Li, G.F. Shao and S.X. Wu

Microarray technology is a powerful tool for human genetic research and other biomedical applications. Numerous improvements to the standard K-means algorithm have been carried out to complete the image segmentation step. However, most of the previous studies classify the image into two clusters. In this paper, we propose a novel K-means algorithm, which .. Read More»

Genet. Mol. Res. 14(3):
2015.July.14.3
DOI:
10.4238/2015.July.14.3
Plant Genetics   Research Article

Dissimilarity between Mouriri elliptica (Mart.) plants cultivated in vitro and in situ through anatomic parameters

Authors: E.S. Assis, A. Rubio Neto, P.D.S. Cabral, F.G. Silva, L.R. Lima and S.C. Vasconcelos Filho

Mouriri elliptica (Mart.) is a genetic resource of the Cerrado domain, which has potential for food and medicinal use. A few studies have been performed on its in vitro propagation, and no studies have examined dissimilarities between plants of this species when cultivated in situ or in vitro. Therefore, the objective of the p.. Read More»

Genet. Mol. Res. 15(4):
gmr.15048885
DOI:
10.4238/gmr.15048885
Bioinformatics   Research Article

SpotWhatR: a user-friendly microarray data analysis system

Authors: Tie Koide, Silvia M. Salem-Izacc, Suely L. Gomes and Ricardo Z.N. VĂ?ÂȘncio

SpotWhatR is a user-friendly microarray data analysis tool that runs under a widely and freely available R statistical language (http://www.r-project.org) for Windows and Linux operational systems. The aim of SpotWhatR is to help the researcher to analyze microarray data by providing basic tools for data visualization, normali.. Read More»

Genet. Mol. Res. 5(1):
Plant Genetics   Research Article

Genetic evaluation of Jatropha curcas: an important oilseed for biodiesel production

Authors: R.G. Freitas, R.F. Missio, F.S. Matos, M.D.V. Resende and L.A.S. Dias

Jatropha curcas, internationally and locally known, respectively, as physic nut and pinhão manso, is a highly promising species for biodiesel production in Brazil and other countries in the tropics. It is rustic, grows in warm regions and is easily cultivated. These characteristics and high-quality oil yields from the s.. Read More»

Genet. Mol. Res. 10(3):
vol10-3gmr1146
DOI:
10.4238/vol10-3gmr1146
Animal Genetics   Research Article

An algorithm to infer similarity among cell types and organisms by examining the most expressed sequences

Authors: S.A.P. Pinto and J.M. Ortega

Following sequence alignment, clustering algorithms are among the most utilized techniques in gene expression data analysis. Clustering gene expression patterns allows researchers to determine which gene expression patterns are alike and most likely to participate in the same biological process being investigated. Gene express.. Read More»

Genet. Mol. Res. 7(3):
vol7-3x-meeting010
DOI:
10.4238/vol7-3x-meeting010
Animal Genetics   Research Article

The full Bayesian significance test for mixture models: results in gene expression clustering

Authors: M.S. Lauretto, C.A.B. Pereira and J.M. Stern

Gene clustering is a useful exploratory technique to group together genes with similar expression levels under distinct cell cycle phases or distinct conditions. It helps the biologist to identify potentially meaningful relationships between genes. In this study, we propose a clustering method based on multivariate normal mixt.. Read More»

Genet. Mol. Res. 7(3):
vol7-3x-meeting06
DOI:
10.4238/vol7-3x-meeting06
Human Genetics   Research Article

Module function and two-way clustering analysis of Epstein-Barr virus-related nasopharyngeal cancer

Authors: F. Chen, J. Liu, M. Fan, X.M. Wei, Y.L. Xie, L.H. Wang and H. Yang

This study sought to identify and characterize the function of genes as diagnostic markers for Epstein-Barr virus (EBV)-related nasopharyngeal cancer (NPC). The gene expression profile of GSE13597 was downloaded from the Gene Expression Omnibus database, which included 28 EBV-related NPC gene expression profile data sets, 25 d.. Read More»

Genet. Mol. Res. 13(1):
http://dx.doi.org/2014.March.17.10
DOI:
http://dx.doi.org/10.4238/2014.March.17.10
Plant Genetics   Research Article

Population structure and genetic diversity of maize inbreds derived from tropical hybrids

Authors: E.C.M. Lanes, J.M.S. Viana, G.P. Paes, M.F.B. Paula, C. Maia, E.T. Caixeta and G.V. Miranda

The objectives of this study were to identify the population structure and to assess the genetic diversity of maize inbreds. We genotyped 81 microsatellite loci of 90 maize inbreds that were derived from tropical hybrids and populations. The population structure analysis was based on a Bayesian approach. Each subpopulation was.. Read More»

Genet. Mol. Res. 13(3):
2014.September.12.2
DOI:
10.4238/2014.September.12.2
Human Genetics   Research Article

Constructing gene network based on biclusters of expression data

Authors: F. Liu, L. Yang, Z.Z. Tian, P. Wu and S.L. Sun

Two genes can be co-regulated and possibly have the similar function if they are similarly expressed, which provides a theoretical basis for construction of gene regulatory networks using gene expression data. Herein, a new method of gene regulatory network was constructed based on biclusters in this paper. Given a bicluster, .. Read More»

Genet. Mol. Res. 15(2):
Bioinformatics   Research Article

A wavelet-based feature vector model for DNA clustering

Authors: J.P. Bao and R.Y. Yuan

DNA data are important in the bioinformatic domain. To extract useful information from the enormous collection of DNA sequences, DNA clustering is often adopted to efficiently deal with DNA data. The alignment-free method is a very popular way of creating feature vectors from DNA sequences, which are then used to compare DNA similarities. This paper propo.. Read More»

Genet. Mol. Res. 14(4):
2015.December.29.26
DOI:
10.4238/2015.December.29.26