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Breast Cancer Cell

Human Genetics   Research Article

MiR-200c inhibits metastasis of breast tumor via the downregulation of Foxf2

Authors: T. Zhang, J.G. Wan, J.B. Liu and M. Deng

The forkhead box F2 (Foxf2) gene suppresses epithelial-mesenchymal transition via the modulation of transcription of zinc finger E-box-binding homeobox 1 (Zeb1) and epithelial (E)-cadherin, thereby inhibiting tumor metastasis. Additionally, the specific binding of microRNA (miR)-200c to Foxf2 mRNA impedes metastatic pulmonary .. Read More»

Genet. Mol. Res. 16(3):
gmr16038971
DOI:
10.4238/gmr16038971