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Plant Genetics   Research Article

Chromosome number variation and evolution in Neotropical Leguminoseae (Mimosoideae) from northeastern Brazil

Authors: E.C.X.R. Santos, R. Carvalho, E.M. Almeida and L.P. Felix

Most members of the subfamily Mimosoideae have pantropical distributions, variable habits, and a basic chromosome number x = 13. We examined karyotypic evolution of 27 species of this subfamily occurring principally in northeastern Brazil by examining chromosomes stained with Giemsa. All of the species had semi-reticulated interphase nuclei and early cond.. Read More»

Genet. Mol. Res. 11(3):
2012.June.27.1
DOI:
10.4238/2012.June.27.1
Animal Genetics   Research Article

Association between HLA-C*04 and American cutaneous leishmaniasis in endemic region of southern Brazil

Authors: R.C. Ribas-Silva, A.D. Ribas, E.C. Ferreira, T.G.V. Silveira and S.D. Borelli

Leishmaniasis is a parasitic infectious disease with global repercussions. American cutaneous leishmaniasis (ACL) is endemic in southern Brazil and its pathogenesis varies according to parasite species, immune response, and host genetics. In terms of immunogenetics, many host genes, including HLA (human leukocyte antigen), cou.. Read More»

Genet. Mol. Res. 14(4):
2015.November.18.58
DOI:
10.4238/2015.November.18.58
Cytogenomics   Research Article

Cytogenetics of the darkling beetles Zophobas aff. confusus and Nyctobates gigas (Coleoptera, Tenebrionidae)

Authors: A.C. Lira-Neto, G.M. Silva, R.C. Moura and M.J. Souza

Males of Zophobas aff. confusus and Nyctobates gigas (Tenebrionidae) collected in the State of Pernambuco, Brazil, were studied through conventional staining, C-banding, silver nitrate impregnation (AgNO3), and the base specific fluorochromes CMA3 and DAPI. Z. aff. confusus was found to have 2n = 20 (9+Xyp) while N. gigas exhibited 2n = 18 (8+neoXY). Larg.. Read More»

Genet. Mol. Res. 11(3):
2012.June.15.5
DOI:
10.4238/2012.June.15.5
Medical Genetics   Research Article

Effect of ABCE1-silencing gene, transfected by electrotransfer, on the proliferation, invasion, and migration of human thyroid carcinoma SW579 cells

Authors: X. Qu and L. Zhang

We investigated the effect of an ABCE1-silencing gene on the proliferation, invasion, and migration of human thyroid carcinoma SW579 cells. We designed and synthesized targeted ABCE1-siRNA sequences and a negative control sequence (NC-siRNA), and transfected them into human thyroid cancer SW579 cells by electrotransfer to obta.. Read More»

Genet. Mol. Res. 14(4):
2015.November.18.32
DOI:
10.4238/2015.November.18.32
Plant Genetics   Research Article

Molecular characterization of an opossum Didelphis albiventris (Marsupialia: Didelphidae) population in an urban fragment of the Brazilian Atlantic Rainforest and support to species barcode identification

Authors: L.C.C. Sousa, C.M.F. Gontijo, G.A. Lacorte, S.N. Meireles, A.P. Silva and C.G. Fonseca

We made a molecular study of 40 opossums, Didelphis albiventris, from an urban fragment of the Atlantic Rainforest in southeastern Brazil, analyzing a 653-bp sequence of cytochrome c oxidase, subunit I. We found three close connected haplotypes, with low nucleotide diversity and a haplotype diversity of 59.1% and confirmed sympatry between D. albiventris .. Read More»

Genet. Mol. Res. 11(3):
2012.June.15.4
DOI:
10.4238/2012.June.15.4
Animal Genetics   Research Article

Isolation and characterization of microsatellite loci in hybrid giant tiger grouper

Authors: Y.S. Huang, Z.B. Li, Y.F. Ning, J.B. Shangguan, Y. Yuan, X.Q. Mao and B.B. Li

The hybrid giant tiger grouper is a fish that has considerable commercial value and has become increasingly important for aquaculture in South East Asia since 2008. In order to prevent any reduction in genetic diversity in hybrid grouper as a result of aquaculture, we have identified 21 microsatellite markers that can be used .. Read More»

Genet. Mol. Res. 14(4):
2015.November.18.35
DOI:
10.4238/2015.November.18.35
Plant Genetics   Research Article

Relationships between four measures of genetic distance and breeding behavior in spring wheat

Authors: G. Benin, G. Matei, A. Costa de Oliveira, G.O. Silva, T.R. Hagemann, C. Lemes da Silva, E.S. Pagliosa and E. Beche

We estimated the genetic distances among 10 spring wheat genotypes based on pedigree data, morphological traits and AFLP markers, used individually and combined with morphological traits, to find the best predictors of general- and specific-combining abilities among parental genotypes. Ten wheat parents were crossed in a diallel form, disregarding recipro.. Read More»

Genet. Mol. Res. 11(3):
2012.June.15.3
DOI:
10.4238/2012.June.15.3
Medical Genetics   Research Article

VKORC1 rs2359612 and rs9923231 polymorphisms correlate with high risks of cardiovascular and cerebrovascular diseases

Authors: Y. Li, J. Zhu and J.Q. Ding

We aimed to confirm the correlations between rs2359612 and rs9923231 single nucleotide polymorphisms (SNPs) in the vitamin K epoxide reductase complex subunit 1 (VKORC1) gene and the risk of cardiovascular and cerebrovascular diseases (CCVDs) using meta-analysis. Electronic databases were exhaustively searched for rel.. Read More»

Genet. Mol. Res. 14(4):
2015.November.18.38
DOI:
10.4238/2015.November.18.38
Human Genetics   Research Article

Molecular diversity and population structure of the forage grass Hemarthria compressa (Poaceae) in south China based on SRAP markers

Authors: L.-K. Huang, X.-Q. Zhang, W.-G. Xie, J. Zhang, L. Cheng and H.D. Yan

Hemarthria compressa is one of the most important and widely utilized forage crops in south China, owing to its high forage yield and capability of adaptation to hot and humid conditions. We examined the population structure and genetic variation within and among 12 populations of H. compressa in south China using sequence-related amplified polymorphism (.. Read More»

Genet. Mol. Res. 11(3):
2012.May.24.3
DOI:
10.4238/2012.May.24.3
Medical Genetics   Research Article

Serum levels of S-100�² correlate with the clinical status and severity of hypoxic-ischemic encephalopathy in neonates

Authors: L.H. Shi, Y. Zhou, M.F. Guo, J.S. Liu, C.X. Li, G.F. Wang, W. Liu and L. Tian

The clinical significance of serum S-100β levels in neonates with hypoxic-ischemic encephalopathy (HIE), as a reference index to assess HIE severity, was evaluated in this study. On the basis of our strict inclusion and exclusion criteria, relevant high-quality case-control studies reporting the association between HIE an.. Read More»

Genet. Mol. Res. 14(4):
2015.November.18.41
DOI:
10.4238/2015.November.18.41