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Bioinformatics   Research Article

Reaction norms for the study of genotype environment interaction for growth and indicator traits of sexual precocity in Nellore cattle

Authors: M.V.A. Lemos, H.L.J. Chiaia, M.P. Berton, F.L.B. Feitosa, C. Aboujaoude,G.C. Venturini, H.N. Oliveira, L.G. Albuquerque and F. Baldi

The objective of this study was to quantify the magnitude of genotype-environment interaction (GxE) effects on age at first calving (AFC), scrotal circumference (SC), and yearling weight (YW) in Nellore cattle using reaction norms. For the study, 89,152 weight records of female and male Nellore animals obtained at yearling age were used. Genetic parameter.. Read More»

Genet. Mol. Res. 14(2):
2015.June.29.9
DOI:
10.4238/2015.June.29.9
Plant Genetics   Research Article

Antiviral RNA silencing suppression activity of Tomato spotted wilt virus NSs protein

Authors: T. Ocampo Ocampo, S.M. Gabriel Peralta, N. Bacheller, S. Uiterwaal, A. Knapp, A. Hennen, D.L. Ochoa-Martinez and H. Garcia-Ruiz

In addition to regulating gene expression, RNA silencing is an essential antiviral defense system in plants. Triggered by double-stranded RNA, silencing results in degradation or translational repression of target transcripts. Viruses are inducers and targets of RNA silencing. To condition susceptibility, most plant viruses en.. Read More»

Genet. Mol. Res. 15(2):
gmr.15028625
DOI:
10.4238/gmr.15028625
Animal Genetics   Research Article

Random regression models for the estimation of genetic and environmental covariance functions for growth traits in Santa Ines sheep

Authors: J.L.R. Sarmento, R.A. Torres, W.H. Sousa, R.N.B. L�´bo,L.G. Albuquerque, P.S. Lopes, N.P.S. Santos and A.B. Bignard

Polynomial functions of different orders were used to model random effects associated with weight of Santa Ines sheep from birth to 196 days. Fixed effects included in the models were contemporary groups, age of ewe at lambing, and fourth-order Legendre polynomials for age to represent the average growth curve. In the random p.. Read More»

Genet. Mol. Res. 15(2):
gmr.15025749
DOI:
10.4238/gmr.15025749
Cytogenomics   Research Article

Immunohistochemistry of lymphocytes in benign lymphoadenosis of oral mucosa

Authors: S.-X. Li, Q. Li, Y.-Q. Yang, L.-J. Jin, Z. Sun and S.-F. Yu

Benign lymphoadenosis of oral mucosa (BLOM) is a common oral mucosa disease and may be regarded as a precancerous lesion. However, the association between its biological behavior and lymphocyte distribution remains unclear. Therefore, to investigate the characteristics of BLOM, we studied the infiltration of lymphocytes associated with it. The expression .. Read More»

Genet. Mol. Res. 14(2):
2015.June.29.10
DOI:
10.4238/2015.June.29.10
Human Genetics   Research Article

Association between the C34T polymorphism of the AMPD1 gene and essential hypertension in Malaysian patients

Authors: R. Nemati, J. Lu, V. Ramachandran, A. Etemad, M. Heidari, M.J. Yahya, R. Roozafzoon and P. Ismail

The aim of this study was to determine whether C34T, a common polymorphism of the adenosine monophosphate deaminase 1 gene (AMPD1), is associated with essential hypertension (EH). We hypothesize that C34T is associated with the development of EH. A case-control design was used for this study. The DNA was extracted using a comm.. Read More»

Genet. Mol. Res. 15(2):
gmr.15026241
DOI:
10.4238/gmr.15026241
Plant Genetics   Research Article

Flow cytometry reliability analysis and variations in sugarcane DNA content

Authors: A.C.L. Oliveira, M. Pasqual, A.T. Bruzi, L.A.S. Pio, P.M.S. Mendon�§a and J.D.R. Soares

The aim of this study was to evaluate the reliability of flow cytometry analysis and the use of this technique to differentiate species and varieties of sugarcane (Saccharum spp) according to their relative DNA content. We analyzed 16 varieties and three species belonging to this genus. To determine a reliable protocol, we evaluated three extraction buffe.. Read More»

Genet. Mol. Res. 14(2):
2015.June.29.11
DOI:
10.4238/2015.June.29.11
Human Genetics   Research Article

Cloprostenol and pregnant mare serum gonadotropin promote estrus synchronization, uterine development, and follicle-stimulating hormone receptor expression in mice

Authors: S. Wei, Z. Gong, L. An, T. Zhang, H. Dai and S. Chen

This study investigated the effects of pregnant mare serum gonadotropin (PMSG) and cloprostenol (CLO) on estrus induction and synchronization, uterine development, and follicle-stimulating hormone receptor (FSHR) expression in mice. A total of 105 Kunming pre-puberty mice were divided into seven subgroups. Three PMSG subgroups were injected intraperitonea.. Read More»

Genet. Mol. Res. 14(2):
2015.June.29.12
DOI:
10.4238/2015.June.29.12
Bioinformatics   Research Article

Bayesian forecasting of temporal gene expression by using an auto regressive panel data approach

Authors: M. Nascimento, F.F. e Silva, T. S�¡fadi, A.C.C. Nascimento, L.M.A. Barroso, L.S. Gl�³ria and B. de S. Carvalho

We propose and evaluate a novel approach for forecasting gene expression over non-observed times in longitudinal trials under a Bayesian viewpoint. One of the aims is to cluster genes that share similar expression patterns over time and then use this similarity to predict relative expression at time points of interest. Express.. Read More»

Genet. Mol. Res. 15(2):
gmr.15027299
DOI:
10.4238/gmr.15027299
Animal Genetics   Research Article

Correlation between PPARg2 gene Pro12Ala polymorphism and cerebral infarction in an Inner Mongolian Han Chinese population

Authors: X. Li, B.L. Zhang*, X.G. Zhang and X.L. Su

The variant of PPAR-g2 has been shown to promote the increase of carotid IMT in patients suffering from cerebral infarction and the Pro12Ala polymorphism in the peroxisome proliferator-activated receptorg2 (PPARg2) gene may be associated with cerebral infarction. However, due to the different genetic background, race, and regi.. Read More»

Genet. Mol. Res. 15(2):
gmr.15027332
DOI:
10.4238/gmr.15027332
Plant Genetics   Research Article

Differential gene expression in drought-tolerant sugarcane roots

Authors: J.S. Vantini, G.C. Dedemo, D.F. Jovino Gimenez, L.F.S. Fonseca, R.I.D. Tezza, M.A. Mutton, J.A. Ferro and M.I.T. Ferro

Drought is one of the most frequent abiotic stresses limiting the productivity and geographical distribution of sugarcane culture. The use of drought-tolerant genotypes is one approach for overcoming the effects of water stress. We conducted a comparative study to identify gene expression profiles under water stress in tolerant sugarcane roots. Two differ.. Read More»

Genet. Mol. Res. 14(2):
2015.June.29.13
DOI:
10.4238/2015.June.29.13