Random regression models for the estimation of genetic and environmental covariance functions for growth traits in Santa Ines sheep
Authors: J.L.R. Sarmento, R.A. Torres, W.H. Sousa, R.N.B. L�´bo,L.G. Albuquerque, P.S. Lopes, N.P.S. Santos and A.B. Bignard
Polynomial functions of different orders were used to model random effects associated with weight of Santa Ines sheep from birth to 196 days. Fixed effects included in the models were contemporary groups, age of ewe at lambing, and fourth-order Legendre polynomials for age to represent the average growth curve. In the random p.. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15025749
- DOI:
- 10.4238/gmr.15025749
Immunohistochemistry of lymphocytes in benign lymphoadenosis of oral mucosa
Authors: S.-X. Li, Q. Li, Y.-Q. Yang, L.-J. Jin, Z. Sun and S.-F. Yu
Benign lymphoadenosis of oral mucosa (BLOM) is a common oral mucosa disease and may be regarded as a precancerous lesion. However, the association between its biological behavior and lymphocyte distribution remains unclear. Therefore, to investigate the characteristics of BLOM, we studied the infiltration of lymphocytes associated with it. The expression .. Read More»
- Genet. Mol. Res. 14(2):
- 2015.June.29.10
- DOI:
- 10.4238/2015.June.29.10
Association between the C34T polymorphism of the AMPD1 gene and essential hypertension in Malaysian patients
Authors: R. Nemati, J. Lu, V. Ramachandran, A. Etemad, M. Heidari, M.J. Yahya, R. Roozafzoon and P. Ismail
The aim of this study was to determine whether C34T, a common polymorphism of the adenosine monophosphate deaminase 1 gene (AMPD1), is associated with essential hypertension (EH). We hypothesize that C34T is associated with the development of EH. A case-control design was used for this study. The DNA was extracted using a comm.. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15026241
- DOI:
- 10.4238/gmr.15026241
Flow cytometry reliability analysis and variations in sugarcane DNA content
Authors: A.C.L. Oliveira, M. Pasqual, A.T. Bruzi, L.A.S. Pio, P.M.S. Mendon�§a and J.D.R. Soares
The aim of this study was to evaluate the reliability of flow cytometry analysis and the use of this technique to differentiate species and varieties of sugarcane (Saccharum spp) according to their relative DNA content. We analyzed 16 varieties and three species belonging to this genus. To determine a reliable protocol, we evaluated three extraction buffe.. Read More»
- Genet. Mol. Res. 14(2):
- 2015.June.29.11
- DOI:
- 10.4238/2015.June.29.11
Cloprostenol and pregnant mare serum gonadotropin promote estrus synchronization, uterine development, and follicle-stimulating hormone receptor expression in mice
Authors: S. Wei, Z. Gong, L. An, T. Zhang, H. Dai and S. Chen
This study investigated the effects of pregnant mare serum gonadotropin (PMSG) and cloprostenol (CLO) on estrus induction and synchronization, uterine development, and follicle-stimulating hormone receptor (FSHR) expression in mice. A total of 105 Kunming pre-puberty mice were divided into seven subgroups. Three PMSG subgroups were injected intraperitonea.. Read More»
- Genet. Mol. Res. 14(2):
- 2015.June.29.12
- DOI:
- 10.4238/2015.June.29.12
Bayesian forecasting of temporal gene expression by using an auto regressive panel data approach
Authors: M. Nascimento, F.F. e Silva, T. S�¡fadi, A.C.C. Nascimento, L.M.A. Barroso, L.S. Gl�³ria and B. de S. Carvalho
We propose and evaluate a novel approach for forecasting gene expression over non-observed times in longitudinal trials under a Bayesian viewpoint. One of the aims is to cluster genes that share similar expression patterns over time and then use this similarity to predict relative expression at time points of interest. Express.. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15027299
- DOI:
- 10.4238/gmr.15027299
Correlation between PPARg2 gene Pro12Ala polymorphism and cerebral infarction in an Inner Mongolian Han Chinese population
Authors: X. Li, B.L. Zhang*, X.G. Zhang and X.L. Su
The variant of PPAR-g2 has been shown to promote the increase of carotid IMT in patients suffering from cerebral infarction and the Pro12Ala polymorphism in the peroxisome proliferator-activated receptorg2 (PPARg2) gene may be associated with cerebral infarction. However, due to the different genetic background, race, and regi.. Read More»
- Genet. Mol. Res. 15(2):
- gmr.15027332
- DOI:
- 10.4238/gmr.15027332
Differential gene expression in drought-tolerant sugarcane roots
Authors: J.S. Vantini, G.C. Dedemo, D.F. Jovino Gimenez, L.F.S. Fonseca, R.I.D. Tezza, M.A. Mutton, J.A. Ferro and M.I.T. Ferro
Drought is one of the most frequent abiotic stresses limiting the productivity and geographical distribution of sugarcane culture. The use of drought-tolerant genotypes is one approach for overcoming the effects of water stress. We conducted a comparative study to identify gene expression profiles under water stress in tolerant sugarcane roots. Two differ.. Read More»
- Genet. Mol. Res. 14(2):
- 2015.June.29.13
- DOI:
- 10.4238/2015.June.29.13
Anti-prostate cancer effects of CTL cell induction in vitro by recombinant adenovirus mediated PSMA/4-1BBL dendritic cells: an immunotherapy study
Authors: C.-G. Sui, D. Wu, F.-D. Meng, M.-H. Yang and Y.-H. Jiang
This study aimed to examine anti-prostate cancer immune response induced by dendritic cells (DCs) transduced with PSMA/4-1BBL recombinant adenoviruses in vitro. Ad-PSMA, Ad-4- 1BBL, and Ad-GFP were transfected into DCs derived from peripheral blood of healthy volunteers. Ad-PSMA/4-1BBL-DC, Ad-PSMA-DC, Ad-4-1BBL-DC, Ad-GFP-DC, and normal-DC, PSMA and 4-1BB.. Read More»
- Genet. Mol. Res. 14(2):
- 2015.June.29.14
- DOI:
- 10.4238/2015.June.29.14
Characterization of microRNAs from goat (Capra hircus) by Solexa deep-sequencing technology
Authors: Y.H. Ling, J.P. Ding, X.D. Zhang, L.J. Wang, Y.H. Zhang, Y.S. Li, Z.J. Zhang and X.R. Zhang
MicroRNAs (miRNAs) are an important class of small noncoding RNAs that are highly conserved in plants and animals. Many miRNAs are known to mediate a myriad of cell processes, including proliferation and differentiation, via the regulation of some transcription and signaling factors, which are closely related to muscle development and disease. In this stu.. Read More»
- Genet. Mol. Res. 12(2):
- 2013.June.13.4
- DOI:
- 10.4238/2013.June.13.4