Overregulation of microRNA-212 in the poor prognosis of esophageal cancer patients
Authors: B. Qi, S.G. Liu, X.G. Qin, W.J. Yao, J.G. Lu, L. Guo, T.Y. Wang, H.C. Li and B.S. Zhao
There have been few reports evaluating the expression and function of the microRNA miR-212 in esophageal cancer. The aim of this study was to investigate the relationship between miR-212 expression and clinicopathological factors and prognoses of esophageal cancer. MicroRNA was extracted from 46 esophageal cancer patients usin.. Read More»
- Genet. Mol. Res. 13(3):
- 2014.September.26.18
- DOI:
- 10.4238/2014.September.26.18
Association between adiponectin receptor 2 gene polymorphisms and cerebral infarction
Authors: B. Yuan and J.F. Teng
We examined the association between the adiponectin receptor 2 gene and the risk of ischemic stroke. Polymerase chain reaction-restriction fragment length polymorphism was used to detect rs12342 genotypes of the adiponectin receptor 2 gene in 300 ischemic stroke patients and 320 age- and gender-matched healthy controls. In the.. Read More»
- Genet. Mol. Res. 13(3):
- 2014.September.26.19
- DOI:
- 10.4238/2014.September.26.19
Relationship between genetic polymorphisms of DNA ligase 1 and non-small cell lung cancer susceptibility and radiosensitivity
Authors: H. Tian, X. He, L. Yin, W.J. Guo, Y.Y. Xia and Z.X. Jiang
The aim of this study was to examine the relationship between genetic polymorphisms in DNA ligase 1 (LIG1) and nonsmall cell lung cancer (NSCLC) susceptibility and radiosensitivity in a Chinese population. This was a case-control study that included 352 NSCLC patients and 448 healthy controls. Polymerase chain reactionrestriction fragment length polymorph.. Read More»
- Genet. Mol. Res. 14(2):
- 2015.June.26.14
- DOI:
- 10.4238/2015.June.26.14
Modification of vectors for functional genomic analysis in plants
Authors: J.T. Li, G. Yu, X.H. Sun, C.G. Jia, Q. Du, Q.Y. Li and H.Y. Pan
Simple, efficient, and economical recombinant plant binary expression vectors for deciphering large-scale functional genomic research in plants and promoting crop improvement by genetically engineering and biotechnology is in great demand. In this research, using the pCHF3, pCAMBIA1301, pCAMBIA3300, pCAMBIA3301 vectors, we suc.. Read More»
- Genet. Mol. Res. 13(3):
- 2014.September.26.20
- DOI:
- 10.4238/2014.September.26.20
Paeonia (Paeoniaceae) expressed sequence tag-derived microsatellite markers transferred to Paeonia delavayi
Authors: D.X. Wang, H. Ma, Y.L. Zhang, A.A. Duan, W.J. Li and Z.H. Li
Paeonia Franchet contains approximately 30 species of perennial herbs and is the only member of the family Paeoniaceae. Paeonia delavayi is an endangered ornamental plant that has a compound flower color and is endemic to southwest China. Its optimal habitats have been fragmented and its population size has greatly decreased as a result of human activitie.. Read More»
- Genet. Mol. Res. 12(2):
- 2013.April.17.6
- DOI:
- 10.4238/2013.April.17.6
Dynamics of chromosomal evolution in the genus Hypsiboas (Anura: Hylidae)
Authors: M.A. Carvalho, M.T. Rodrigues, S. Siqueira and C. Garcia
Hylidae is one of the most species-rich families of anurans, and 40% of representatives in this group occur in Brazil. In spite of such remarkable diversity, little is known about this family and its taxonomical and systematic features. Most hylids have 2n = 24, even though most of the cytogenetic data are mainly obtained base.. Read More»
- Genet. Mol. Res. 13(3):
- 2014.September.26.21
- DOI:
- 10.4238/2014.September.26.21
Expression and clinical significance of PIWIL2 in hilar cholangiocarcinoma tissues and cell lines
Authors: Y.J. Chen, X.F. Xiong, S.Q. Wen, L. Tian, W.L. Cheng and Y.Q. Qi
The objective of this study was to explore the relationship between PIWI-like protein 2 (PIWIL2) and clinicopathological characteristics and prognosis after radical resection. To accomplish this, we analyzed PIWIL2 expression in hilar cholangiocarcinoma tissues and cell lines. PIWIL2 expression was detected by immunohistochemistry in 41 hilar cholangiocar.. Read More»
- Genet. Mol. Res. 14(2):
- 2015.June.26.15
- DOI:
- 10.4238/2015.June.26.15
DNA methylation involved in proline accumulation in response to osmotic stress in rice (Oryza sativa)
Authors: C.Y. Zhang, N.N. Wang, Y.H. Zhang, Q.Z. Feng, C.W. Yang and B. Liu
Proline accumulation is involved in plant osmotic stress tolerance. Given that DNA methylation is related to almost all metabolic processes through regulation of gene expression, we suspected that this epigenetic modification and proline biosynthesis are probably related. To test this, we investigated whether osmotic stress-induced proline accumulation is.. Read More»
- Genet. Mol. Res. 12(2):
- 2013.April.17.5
- DOI:
- 10.4238/2013.April.17.5
Genome-wide identification and phylogenetic analysis of the AP2/ERF gene superfamily in sweet orange (Citrus sinensis)
Authors: T.M. Ito, P.B. Polido, M.C. Rampim, G. Kaschuk and S.G.H. Souza
Sweet orange (Citrus sinensis) plays an important role in the economy of more than 140 countries, but it is grown in areas with intermittent stressful soil and climatic conditions. The stress tolerance could be addressed by manipulating the ethylene response factor (ERF) transcription factors because they orchestrate .. Read More»
- Genet. Mol. Res. 13(3):
- 2014.September.26.22
- DOI:
- 10.4238/2014.September.26.22
Sublingual vein parameters, AFP, AFP-L3,and GP73 in patients with hepatocellularcarcinoma
Authors: J. Zhao, L.-Y. Guo, J.-M. Yang and J.-W. Jia
This study evaluated the diagnostic value of alphafetoprotein (AFP), AFP heterogeneity 3 (AFP-L3), Golgi protein 73 (GP73), and sublingual vein parameters in hepatocellular carcinoma (HCC). Levels of serum AFP, AFP-L3, GP73, and sublingual vein scores were measured in 34 patients with chronic hepatitis, 65 patients with post-hepatitis B cirrhosis, 71 pati.. Read More»
- Genet. Mol. Res. 14(2):
- 2015.June.26.16
- DOI:
- 10.4238/2015.June.26.16