Association between interleukin gene polymorphisms and risk of recurrent oral ulceration
Authors: C. Jing and J.-Q. Zhang
We conducted a case-control study to investigate the association between the functional IL-1β+3954 (C/T), IL-6-174 (G/C), IL-10-1082 (G/A), and IL-10-819C/T genetic polymorphisms and risk of recurrent oral ulceration (ROU) in a Chinese population. Polymorphisms of IL-1β+3954C/T, IL-6-174G/C, IL-10-1082A/G and IL-10-819C/T were assessed by polyme.. Read More»
- Genet. Mol. Res. 14(2):
- 2015.June.18.26
- DOI:
- 10.4238/2015.June.18.26
Genetic background of Escherichia coli isolates from peritoneal dialysis patients with peritonitis and uninfected control subjects
Authors: Y.F. Li1,, N. Su, S.Y. Chen, W.X. Hu, F.F. Li, Z.P. Jiang and X.Q. Yu
Escherichia coli is the most common cause of Gram-negative peritonitis resulting in peritoneal function deterioration as well as poor clinical outcome in continuous ambulatory peritoneal dialysis (PD) patients. In this study, we analyzed the phylogenetic background and genetic profile of the E. coli isolates and sought to dete.. Read More»
- Genet. Mol. Res. 15(1):
- gmr.15017341
- DOI:
- 10.4238/gmr.15017341
Expression and significance of S100P, CD147, and OCT4 in different prostate cancer tissue TNM stages
Authors: Q. Wang, J.G. Zhang and W. Wang
The aim of this project was to investigate the expression and significance of S100P, CD147, and OCT4 in prostate cancer tissue at different TNM stages. We enrolled 54 patients with prostate cancer, 40 with benign prostatic hyperplasia, and 20 subjects with normal prostates. S100P, CD147, and OCT4 were detected by immunohistochemistry. The positive rate of.. Read More»
- Genet. Mol. Res. 14(2):
- 2015.June.18.27
- DOI:
- 10.4238/2015.June.18.27
Development and characterization of novel microsatellite markers for Ginkgo biloba using 454 pyrosequencing
Authors: Q. Zhou, X.X. Wang, M. Xu, F.L. Cao, F.X. Yu and L.A. Xu
As a “living fossil” that is used to understand the evolutionary history of seed plants, Ginkgo biloba is a well-known multipurpose tree with edible seeds, medicinal properties, and ornamental value, but little is known about its genetic diversity. Microsatellite, or simple sequence repeat (SSR), markers have prove.. Read More»
- Genet. Mol. Res. 15(1):
- gmr.15017385
- DOI:
- 10.4238/gmr.15017385
Genetic analysis of water-deficit response traits in maize
Authors: M. Ahmad, M. Saleem, M. Ahsan and A. Ahmad
A set of sixty inbred lines of maize (Zea mays L.) were screened in the greenhouse at the seedling stage under both normal and water-deficit conditions. Six water deficit-tolerant inbred lines were selected based on root to shoot ratios. These selected lines were crossed in a diallel pattern. The parental, F1, and reciprocal c.. Read More»
- Genet. Mol. Res. 15(1):
- gmr.15017459
- DOI:
- 10.4238/gmr.15017459
Association between the MTHFR C677T gene polymorphism and essential hypertension in South West Cameroon
Authors: S.M. Ghogomu, N.E. Ngolle, R.N. Mouliom and B.F. Asa
The association of the methylenetetrahydrofolate reductase (MTHFR) C677T gene polymorphism and essential hypertension has been reported but with controversial results in diverse populations in Asia and Europe, thereby suggesting a dependency on ethnicity. The aim of this study was to investigate the association between the MTHFR C677T polymorphism and ess.. Read More»
- Genet. Mol. Res. 15(1):
- gmr.15017462
- DOI:
- 10.4238/gmr.15017462
Analysis of DRB3 gene polymorphisms in Jafarabadi, Mediterranean, and Murrah buffaloes from Brazil
Authors: N.B. Stafuzza, L.M. Olivatto, B.C.M. Naressi, H. Tonhati and M.E.J. Amaral-Trusty
The DRB3 gene is an MHC class II gene that has a high degree of polymorphism with more than 100 alleles described in cattle. This variation contributes to differences among individuals in immune responsiveness and disease resistance. In this study, we searched for allelic variants in exon 2 of the DRB3 gene in 80 river buffaloes of three breeds in Brazil .. Read More»
- Genet. Mol. Res. 15(1):
- gmr.15016368
- DOI:
- 10.4238/gmr.15016368
Effect of procyanidine on VEGFR-2 expression and transduction pathway in rat endothelial progenitor cells under high glucose conditions
Authors: Y. Liu, W.-J. Liao, Z. Zhu, H. Zeng, H.-Q. He, X.-L. Sun, X.-F. Xu, L. Huang, W.-M. Wang, X.-Y. Zhou and Y.-Z. He
The protective effect of procyanidine and its oligomers against high glucose-mediated oxidative stress injury in endothelial progenitor cells (EPCs), and effect of procyanidin on vascular endothelial growth factor receptor-2 (VEGFR-2) expression and downstream signal pathway were analyzed in vitro. Rat bone marrow mononuclear cells were isolated, cultured.. Read More»
- Genet. Mol. Res. 15(1):
- gmr.15016925
- DOI:
- 10.4238/gmr.15016925
High levels of polymorphism found through cross-amplification of microsatellite loci in a Ctenomys pearsoni (Rodentia, Ctenomyidae) population
Authors: N. Mannise, S. Gonz�¡lez, J.E. Maldonado, G. Izquierdo, G. Francescoli and M. Cosse
Ctenomys pearsoni (Pearson’s tuco-tuco) is a subterranean rodent native to Uruguay. We tested the amplification pattern of 12 microsatellite loci, designed for C. sociabilis and C. haigi in a C. pearsoni population. DNA extractions were made from hair samples, and PCR amplification products were run on an ABI 3100 microcapillary gel. Eight loci were.. Read More»
- Genet. Mol. Res. 12(2):
- 2013.April.2.5
- DOI:
- 10.4238/2013.April.2.5
Gene expression study related with the intrinsic pathway of apoptosis in bladder cancer by real-time PCR technique
Authors: D.F. Barione, F.S.N. Lizarte, P.C. Novais, C.A.M. de Carvalho, F.C.B. Valeri, F.M. Peria, H.F. de Oliveira, D.L. Zanette, W.A. Silva Jr., A.J. Cologna, R.B. Reis, S. Tucci Jr., A.C.P. Martins, D.P.C. Tirapelli and L.F. Tirapelli
We examined the expression of anti-apoptotic genes (XIAP and Bcl-2) and apoptotic genes (cytochrome c, caspase-9, Apaf-1) in tissue samples of patients with superficial bladder cancer. Thirty-two bladder cancer tissue samples (8 papillary urothelial neoplasm of low malignant potential, 10 low-grade, and 14 high-grade) and 8 normal bladder tissue samples f.. Read More»
- Genet. Mol. Res. 12(2):
- 2013.April.2.4
- DOI:
- 10.4238/2013.April.2.4