A new method for estimating the number of non-differentially expressed genes
Authors: J. Wu, C.Y. Liu, W.T. Chen, W.Y. Ma and Y. Ding
Control of the false discovery rate is a statistical method that is widely used when identifying differentially expressed genes in high-throughput sequencing assays. It is often calculated using an adaptive linear step-up procedure in which the number of non-differentially expressed genes should be estimated accurately. In this paper, we discuss the estim.. Read More»
- Genet. Mol. Res. 15(1):
- gmr.15017402
- DOI:
- 10.4238/gmr.15017402
Prediction of health risk due to polycyclic aromatic hydrocarbons present in urban air in Rio de Janeiro, Brazil
Authors: C.R. Rainho, A.M.A. Velho, S.M. Corr�ªa, J.L. Mazzei, C.A.F. Aiub and I. Felzenszwalb
Risk assessment can provide a comprehensive estimate of potential effects of contaminants under specific, well-defined, and well-described circumstances, providing quantitative relationships between exposure and effects to identify and to define areas of concern. We investigated the mutagenic activity of particulate matter in air samples collected from th.. Read More»
- Genet. Mol. Res. 12(3):
- 2013.February.28.6
- DOI:
- 10.4238/2013.February.28.6
FOXO1 is a tumor suppressor in cervical cancer
Authors: B. Zhang, L.S. Gui, X.L. Zhao, L.L. Zhu and Q.W. Li
Forkhead box protein O1 (FOXO1) is an important transcriptional regulator of cell proliferation, and is considered essential for tumor growth and progression. However, the function of FOXO1 in human cervical cancer remains unclear. In this study, we investigated the role of FOXO1 in cervical cancer. Our results showed that FOXO1 expression was lower in ce.. Read More»
- Genet. Mol. Res. 14(2):
- 2015.June.18.3
- DOI:
- 10.4238/2015.June.18.3
Clinical features and treatment of endophthalmitis after cataract surgery
Authors: J. Zhu and Z.H. Li
The aim of this study was to investigate the clinical features and treatment results of endophthalmitis after cataract surgery. Five patients with endophthalmitis after phacoemulsification with intraocular lens implantation were enrolled in this study. The pathogenesis, clinical manifestation, and surgical outcomes of 5 patients were compared. Three patie.. Read More»
- Genet. Mol. Res. 14(2):
- 2015.June.18.4
- DOI:
- 10.4238/2015.June.18.4
Karyotype structure of Hypostomus cf. plecostomus (Linnaeus, 1758) from Tapaj�³s River basin, Southern Amazon: occurrence of sex chromosomes (ZZ/ZW) and their evolutionary implications
Authors: L.C. Oliveira, M.O. Ribeiro, E.S. Dutra, C.H. Zawadzki, A.L.B. Portela-Castro5 and I.C. Martins-Santos
Hypostomus is a group of fish with numerical and structural karyotypic variability. Among them, only six species, three of which belong to the Amazon basin, show a sex chromosome. In this study, we present the karyotype structure of Hypostomus cf. plecostomus from the Teles Pires river basin in the municipality of Alta Floresta, MT. The species has 2n = 6.. Read More»
- Genet. Mol. Res. 14(2):
- 2015.June.18.5
- DOI:
- 10.4238/2015.June.18.5
Molecular characterization of endophytes isolated from Saccharum spp based on esterase and ribosomal DNA (ITS1-5.8S-ITS2) analyses
Authors: A.C. Leme, M.R.R. Bevilaqua, S.A. Rhoden, C.A. Mangolin, M.F.P.S. Machado and J.A. Pamphile
This study used esterases and ribosomal DNA (rDNA) markers to determine endophytic variability in order to better understand endophyte-host interactions. Polyacrylamide gel electrophoresis and esterase isoenzymes (EST; EC 3.1.1.3), with a-naphthyl acetate and β-naphthyl acetate as substrates, were used to assess relationships among endophytes. ITS1-5.. Read More»
- Genet. Mol. Res. 12(3):
- 2013.September.27.11
- DOI:
- 10.4238/2013.September.27.11
Fast protocol for extraction of DNA from Prosopis spp leaves (plant adapted to arid environment) without liquid nitrogen
Authors: C.Y. Michel-L�³pez, D. Gonz�¡lez-Mendoza and O. Grimaldo-Juarez
The extraction of high-quality genomic DNA from Prosopis spp for polymerase chain reaction (PCR) amplification is complicated, owing to the presence of a high percentage of secondary metabolites that bind to or co-precipitate with nucleic acids. In the present study, we report a modified sodium dodecyl sulfate/phenol protocol that eliminates the use of li.. Read More»
- Genet. Mol. Res. 12(3):
- 2013.September.27.10
- DOI:
- 10.4238/2013.September.27.10
DNA barcoding of populations of Fallopia multiflora, an indigenous herb in China
Authors: X.Q. Sun, M.M. Bai, H. Yao, J.L. Guo, M.M. Li and Y.Y. Hang
Fallopia multiflora, locally known as Heshouwu, is one of the most important and widely used Chinese medicinal herbs. However, there is still considerable confusion concerning its different provenances. DNA barcoding is a recent aid to taxonomic identification and uses a short standardized DNA region to discriminate plant species. We assessed the applicab.. Read More»
- Genet. Mol. Res. 12(3):
- 2013.September.27.9
- DOI:
- 10.4238/2013.September.27.9
Identification of a locus characteristic of male individuals of buffalo grass [Buchloe dactyloides (Nutt.) Engelm.] by using an RAPD marker
Authors: Y.X. Li, X.G. Wang, C.H. Yang, L.L. Cong, F.F. Wu, J.G. Xue and Y.H. Han
Buffalo grass [Buchloe dactyuloides (Nutt.) Engelm.] plants can be either male, female, or hermaphrodite (monoecious). As there is no morphological difference in the early vegetative growth of these three classes of plants, it is worthwhile to use molecular biological methods to attempt to identify the sex of a plant at this early growth period. In this s.. Read More»
- Genet. Mol. Res. 12(3):
- 2013.September.27.8
- DOI:
- 10.4238/2013.September.27.8
Nucleolar-persistence phenomenon during spermatogenesis in genus Meccus (Hemiptera, Triatominae)
Authors: F.F. Madeira, A.A.C. Lima, J.A. Rosa, M.T.V. Azeredo-Oliveira and K.C.C. Alevi
The Triatominae subfamily consists of 150 species in 18 genera, grouped into six tribes. In cytogenetics, triatomines are important biological models because they have holocentric chromosomes and nucleolar persistence in meiosis. The phenomenon of nucleolar persistence has been described for 23 species of triatomine in three g.. Read More»
- Genet. Mol. Res. 15(1):
- gmr.15017427
- DOI:
- 10.4238/gmr.15017427